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cyp2y3 cytochrome P450, family 2, subfamily Y, polypeptide 3 [ Danio rerio (zebrafish) ]

Gene ID: 368352, updated on 9-Dec-2024

Summary

Official Symbol
cyp2y3provided by ZNC
Official Full Name
cytochrome P450, family 2, subfamily Y, polypeptide 3provided by ZNC
Primary source
ZFIN:ZDB-GENE-050522-490
See related
Ensembl:ENSDARG00000101423 AllianceGenome:ZFIN:ZDB-GENE-050522-490
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
sb:cb637; im:6903403; zgc:110692
Summary
Predicted to enable heme binding activity and oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen. Predicted to be involved in organic acid metabolic process and xenobiotic metabolic process. Predicted to be active in cytoplasm and intracellular membrane-bounded organelle. Is expressed in several structures, including EVL; pectoral fin musculature; periderm; visual system; and yolk syncytial layer. Human ortholog(s) of this gene implicated in several diseases, including drug dependence (multiple); gastrointestinal system cancer (multiple); glucose metabolism disease (multiple); liver disease (multiple); and lung disease (multiple). Orthologous to several human genes including CYP2A13 (cytochrome P450 family 2 subfamily A member 13). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
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Genomic context

See cyp2y3 in Genome Data Viewer
Location:
chromosome: 15
Exon count:
9
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 15 NC_007126.7 (26041..32151, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 15 NC_007126.6 (97182..104342, complement)

Chromosome 15 - NC_007126.7Genomic Context describing neighboring genes Neighboring gene si:zfos-411a11.2 Neighboring gene si:ch1073-83n3.2 Neighboring gene AXL receptor tyrosine kinase Neighboring gene uncharacterized LOC103908784

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

General gene information

Gene Ontology Provided by ZFIN

Process Evidence Code Pubs
involved_in organic acid metabolic process  
involved_in xenobiotic metabolic process  
Component Evidence Code Pubs
is_active_in cytoplasm  
is_active_in intracellular membrane-bounded organelle  

General protein information

Preferred Names
cytochrome P450 2Y3
Names
cytochrome P450 CYP2Y3
NP_001018658.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001020822.1NP_001018658.1  cytochrome P450 2Y3

    See identical proteins and their annotated locations for NP_001018658.1

    Status: PROVISIONAL

    Source sequence(s)
    BC095374
    UniProtKB/TrEMBL
    Q4VBR9
    Related
    ENSDARP00000135608.1, ENSDART00000164323.2
    Conserved Domains (1) summary
    pfam00067
    Location:40487
    p450; Cytochrome P450

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007126.7 Reference GRCz11 Primary Assembly

    Range
    26041..32151 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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