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GRB10 growth factor receptor bound protein 10 [ Homo sapiens (human) ]

Gene ID: 2887, updated on 10-Dec-2024

Summary

Official Symbol
GRB10provided by HGNC
Official Full Name
growth factor receptor bound protein 10provided by HGNC
Primary source
HGNC:HGNC:4564
See related
Ensembl:ENSG00000106070 MIM:601523; AllianceGenome:HGNC:4564
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
RSS; IRBP; MEG1; GRB-IR; Grb-10
Summary
The product of this gene belongs to a small family of adapter proteins that are known to interact with a number of receptor tyrosine kinases and signaling molecules. This gene encodes a growth factor receptor-binding protein that interacts with insulin receptors and insulin-like growth-factor receptors. Overexpression of some isoforms of the encoded protein inhibits tyrosine kinase activity and results in growth suppression. This gene is imprinted in a highly isoform- and tissue-specific manner, with expression observed from the paternal allele in the brain, and from the maternal allele in the placental trophoblasts. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Oct 2010]
Expression
Ubiquitous expression in thyroid (RPKM 6.6), kidney (RPKM 5.7) and 25 other tissues See more
Orthologs
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Genomic context

See GRB10 in Genome Data Viewer
Location:
7p12.1
Exon count:
32
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 7 NC_000007.14 (50590068..50793453, complement)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 7 NC_060931.1 (50751214..50954643, complement)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 7 NC_000007.13 (50657765..50861150, complement)

Chromosome 7 - NC_000007.14Genomic Context describing neighboring genes Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr7:50514049-50515248 Neighboring gene Sharpr-MPRA regulatory region 9826 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 18183 Neighboring gene fidgetin like 1 Neighboring gene VISTA enhancer hs2059 Neighboring gene H3K4me1 hESC enhancers GRCh37_chr7:50569579-50570080 and GRCh37_chr7:50570081-50570580 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr7:50581285-50581919 Neighboring gene dopa decarboxylase Neighboring gene Neanderthal introgressed variant-containing enhancers experimental_99424 and experimental_99425 Neighboring gene P300/CBP strongly-dependent group 1 enhancer GRCh37_chr7:50598907-50600106 Neighboring gene BRD4-independent group 4 enhancer GRCh37_chr7:50602470-50603669 Neighboring gene DDC antisense RNA 1 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr7:50637965-50638490 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_99443 Neighboring gene uncharacterized LOC124901632 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr7:50720584-50721214 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_99457 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_99465 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr7:50736937-50737438 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr7:50737439-50737938 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr7:50782907-50783422 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_99483 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr7:50836560-50837139 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr7:50837140-50837720 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr7:50875755-50876262 Neighboring gene Sharpr-MPRA regulatory region 14531 Neighboring gene MED14-independent group 3 enhancer GRCh37_chr7:50894096-50895295 Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr7:50905976-50907175 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr7:50920730-50921230 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr7:50921231-50921731 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr7:50935547-50936047 Neighboring gene ribosomal protein L39 pseudogene 23 Neighboring gene H3K27ac hESC enhancer GRCh37_chr7:50954893-50955392 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr7:50966118-50966911 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr7:50966912-50967704 Neighboring gene MPRA-validated peak6518 silencer Neighboring gene small nucleolar RNA SNORA4

Genomic regions, transcripts, and products

Expression

  • Project title: Tissue-specific circular RNA induction during human fetal development
  • Description: 35 human fetal samples from 6 tissues (3 - 7 replicates per tissue) collected between 10 and 20 weeks gestational time were sequenced using Illumina TruSeq Stranded Total RNA
  • BioProject: PRJNA270632
  • Publication: PMID 26076956
  • Analysis date: Mon Apr 2 22:54:59 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Phenotypes

Copy number response

Description
Copy number response
Haploinsufficency

No evidence available (Last evaluated 2012-03-23)

ClinGen Genome Curation Page
Triplosensitivity

No evidence available (Last evaluated 2012-03-23)

ClinGen Genome Curation Page

EBI GWAS Catalog

Description
A genetic locus in 7p12.2 associated with treatment resistant schizophrenia.
EBI GWAS Catalog
A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance.
EBI GWAS Catalog
Gene-Smoking Interactions Identify Several Novel Blood Pressure Loci in the Framingham Heart Study.
EBI GWAS Catalog
Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture.
EBI GWAS Catalog
Identification of novel genetic markers associated with clinical phenotypes of systemic sclerosis through a genome-wide association strategy.
EBI GWAS Catalog
Novel susceptibility variants at 10p12.31-12.2 for childhood acute lymphoblastic leukemia in ethnically diverse populations.
EBI GWAS Catalog

Pathways from PubChem

Interactions

General gene information

Clone Names

  • KIAA0207

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables identical protein binding PubMed 
enables insulin receptor binding  
enables insulin receptor binding PubMed 
enables protein binding PubMed 
enables signaling receptor complex adaptor activity  
Process Evidence Code Pubs
involved_in ERK1 and ERK2 cascade  
involved_in gene expression  
involved_in insulin receptor signaling pathway  
involved_in insulin receptor signaling pathway  
involved_in insulin-like growth factor receptor signaling pathway  
involved_in negative regulation of D-glucose import PubMed 
involved_in negative regulation of Wnt signaling pathway  
involved_in negative regulation of Wnt signaling pathway PubMed 
involved_in negative regulation of glycogen biosynthetic process  
involved_in negative regulation of insulin receptor signaling pathway  
involved_in negative regulation of insulin receptor signaling pathway PubMed 
involved_in positive regulation of cold-induced thermogenesis PubMed 
involved_in positive regulation of phosphorylation  
involved_in positive regulation of vascular endothelial growth factor receptor signaling pathway PubMed 
involved_in response to insulin  
involved_in vascular associated smooth muscle cell migration  
Component Evidence Code Pubs
located_in cytoplasm PubMed 
located_in cytosol  
located_in plasma membrane PubMed 
part_of protein-containing complex PubMed 

General protein information

Preferred Names
growth factor receptor-bound protein 10
Names
GRB10 adapter protein
GRB10 adaptor protein
insulin receptor-binding protein Grb-IR
maternally expressed gene 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_012305.2 RefSeqGene

    Range
    5010..208395
    Download
    GenBank, FASTA, Sequence Viewer (Graphics), LRG_1032

mRNA and Protein(s)

  1. NM_001001549.3NP_001001549.1  growth factor receptor-bound protein 10 isoform b

    See identical proteins and their annotated locations for NP_001001549.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (2), also known as hGrb10alpha, lacks an in-frame segment in the coding region, compared to variant 1. It encodes a shorter isoform (b), that is missing an internal segment compared to isoform a.
    Source sequence(s)
    AC005153, AC080092
    Consensus CDS
    CCDS47586.1
    UniProtKB/Swiss-Prot
    Q13322
    Related
    ENSP00000349818.5, ENST00000357271.9
    Conserved Domains (4) summary
    cd01787
    Location:166248
    GRB7_RA; RA (RAS-associated like) domain of Grb7
    cd10415
    Location:441548
    SH2_Grb10; Src homology 2 (SH2) domain found in the growth factor receptor bound, subclass 10 (Grb10) proteins
    cd01259
    Location:283362
    PH_APBB1IP; Amyloid beta (A4) Precursor protein-Binding, family B, member 1 Interacting Protein pleckstrin homology (PH) domain
    pfam08947
    Location:380421
    BPS; BPS (Between PH and SH2)
  2. NM_001001550.3NP_001001550.1  growth factor receptor-bound protein 10 isoform c

    See identical proteins and their annotated locations for NP_001001550.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (3), also known as hGrb10beta, differs in the 5' UTR and the 5' coding region, compared to variant 1. The resulting isoform (c) has a shorter N-terminus when compared to isoform a. Isoform c is encoded by transcript variants 4, 6, and 7.
    Source sequence(s)
    AC005153, AC080092
    Consensus CDS
    CCDS43583.1
    UniProtKB/Swiss-Prot
    Q13322
    Related
    ENSP00000381790.2, ENST00000398810.6
    Conserved Domains (4) summary
    cd10415
    Location:429536
    SH2_Grb10; Src homology 2 (SH2) domain found in the growth factor receptor bound, subclass 10 (Grb10) proteins
    cd01259
    Location:228350
    PH_APBB1IP; Amyloid beta (A4) Precursor protein-Binding, family B, member 1 Interacting Protein pleckstrin homology (PH) domain
    cd16141
    Location:108199
    RA_GRB10; Ras-associating (RA) domain found in growth factor receptor-bound (Grb) protein 10
    pfam08947
    Location:368409
    BPS; BPS (Between PH and SH2)
  3. NM_001001555.3NP_001001555.1  growth factor receptor-bound protein 10 isoform c

    See identical proteins and their annotated locations for NP_001001555.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (4) differs in the 5' UTR and the 5' coding region, compared to variant 1. The resulting isoform (c) has a shorter N-terminus when compared to isoform a. Isoform c is encoded by transcript variants 3, 4, 6, and 7.
    Source sequence(s)
    AC004920, AC005153, AC080092
    Consensus CDS
    CCDS43583.1
    UniProtKB/Swiss-Prot
    Q13322
    Related
    ENSP00000338543.3, ENST00000335866.7
    Conserved Domains (4) summary
    cd10415
    Location:429536
    SH2_Grb10; Src homology 2 (SH2) domain found in the growth factor receptor bound, subclass 10 (Grb10) proteins
    cd01259
    Location:228350
    PH_APBB1IP; Amyloid beta (A4) Precursor protein-Binding, family B, member 1 Interacting Protein pleckstrin homology (PH) domain
    cd16141
    Location:108199
    RA_GRB10; Ras-associating (RA) domain found in growth factor receptor-bound (Grb) protein 10
    pfam08947
    Location:368409
    BPS; BPS (Between PH and SH2)
  4. NM_001350814.2NP_001337743.1  growth factor receptor-bound protein 10 isoform a

    Status: REVIEWED

    Description
    Transcript Variant: This variant (1) encodes isoform a.
    Source sequence(s)
    AC004920, AC005153, AC080092
    Consensus CDS
    CCDS43582.1
    UniProtKB/Swiss-Prot
    A4D258, A7VJ95, A8K0E6, D3DVM9, O00427, O00701, O75222, Q13322, Q92606, Q92907, Q92948
    Related
    ENSP00000385770.1, ENST00000401949.6
    Conserved Domains (4) summary
    cd01787
    Location:166248
    GRB7_RA; RA (RAS-associated like) domain of Grb7
    cd10415
    Location:487594
    SH2_Grb10; Src homology 2 (SH2) domain found in the growth factor receptor bound, subclass 10 (Grb10) proteins
    cd01259
    Location:286408
    PH_APBB1IP; Amyloid beta (A4) Precursor protein-Binding, family B, member 1 Interacting Protein pleckstrin homology (PH) domain
    pfam08947
    Location:426467
    BPS; BPS (Between PH and SH2)
  5. NM_001350815.2NP_001337744.1  growth factor receptor-bound protein 10 isoform d

    Status: REVIEWED

    Description
    Transcript Variant: This variant (5) encodes isoform d.
    Source sequence(s)
    AC004920, AC005153, AC080092
    Consensus CDS
    CCDS87504.1
    UniProtKB/TrEMBL
    A0A2R8YCL1
    Related
    ENSP00000493728.1, ENST00000644879.1
    Conserved Domains (4) summary
    cd01787
    Location:204286
    GRB7_RA; RA (RAS-associated like) domain of Grb7
    cd10415
    Location:525632
    SH2_Grb10; Src homology 2 (SH2) domain found in the growth factor receptor bound, subclass 10 (Grb10) proteins
    cd01259
    Location:324446
    PH_APBB1IP; Amyloid beta (A4) Precursor protein-Binding, family B, member 1 Interacting Protein pleckstrin homology (PH) domain
    pfam08947
    Location:464505
    BPS; BPS (Between PH and SH2)
  6. NM_001350816.3NP_001337745.2  growth factor receptor-bound protein 10 isoform c

    Status: REVIEWED

    Description
    Transcript Variant: This variant (6), as well as variants 3, 4, and 7, encodes isoform c.
    Source sequence(s)
    AC004920, AC005153, AC080092
    Consensus CDS
    CCDS43583.1
    Conserved Domains (4) summary
    cd10415
    Location:429536
    SH2_Grb10; Src homology 2 (SH2) domain found in the growth factor receptor bound, subclass 10 (Grb10) proteins
    cd01259
    Location:228350
    PH_APBB1IP; Amyloid beta (A4) Precursor protein-Binding, family B, member 1 Interacting Protein pleckstrin homology (PH) domain
    cd16141
    Location:108199
    RA_GRB10; Ras-associating (RA) domain found in growth factor receptor-bound (Grb) protein 10
    pfam08947
    Location:368409
    BPS; BPS (Between PH and SH2)
  7. NM_001371008.1NP_001357937.1  growth factor receptor-bound protein 10 isoform c

    Status: REVIEWED

    Description
    Transcript Variant: This variant (7), as well as variants 3, 4, and 6, encodes isoform c.
    Source sequence(s)
    AC004920, AC005153, AC080092
    Consensus CDS
    CCDS43583.1
    Related
    ENSP00000495341.2, ENST00000645075.2
    Conserved Domains (4) summary
    cd10415
    Location:429536
    SH2_Grb10; Src homology 2 (SH2) domain found in the growth factor receptor bound, subclass 10 (Grb10) proteins
    cd01259
    Location:228350
    PH_APBB1IP; Amyloid beta (A4) Precursor protein-Binding, family B, member 1 Interacting Protein pleckstrin homology (PH) domain
    cd16141
    Location:108199
    RA_GRB10; Ras-associating (RA) domain found in growth factor receptor-bound (Grb) protein 10
    pfam08947
    Location:368409
    BPS; BPS (Between PH and SH2)
  8. NM_001371009.1NP_001357938.1  growth factor receptor-bound protein 10 isoform f

    Status: REVIEWED

    Description
    Transcript Variant: This variant (8) encodes the longest isoform (f).
    Source sequence(s)
    AC004920, AC005153, AC080092
    Conserved Domains (3) summary
    cd10415
    Location:536643
    SH2_Grb10; Src homology 2 (SH2) domain found in the growth factor receptor bound, subclass 10 (Grb10) proteins
    cd01259
    Location:335457
    PH_APBB1IP; Amyloid beta (A4) Precursor protein-Binding, family B, member 1 Interacting Protein pleckstrin homology (PH) domain
    cd16141
    Location:215306
    RA_GRB10; Ras-associating (RA) domain found in growth factor receptor-bound (Grb) protein 10

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000007.14 Reference GRCh38.p14 Primary Assembly

    Range
    50590068..50793453 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017012061.3XP_016867550.1  growth factor receptor-bound protein 10 isoform X11

    Conserved Domains (4) summary
    cd01787
    Location:154235
    GRB7_RA; RA (RAS-associated like) domain of Grb7
    cd10415
    Location:474581
    SH2_Grb10; Src homology 2 (SH2) domain found in the growth factor receptor bound, subclass 10 (Grb10) proteins
    cd01259
    Location:273395
    PH_APBB1IP; Amyloid beta (A4) Precursor protein-Binding, family B, member 1 Interacting Protein pleckstrin homology (PH) domain
    pfam08947
    Location:413454
    BPS; BPS (Between PH and SH2)
  2. XM_047420243.1XP_047276199.1  growth factor receptor-bound protein 10 isoform X10

  3. XM_047420233.1XP_047276189.1  growth factor receptor-bound protein 10 isoform X6

  4. XM_047420241.1XP_047276197.1  growth factor receptor-bound protein 10 isoform X8

    UniProtKB/Swiss-Prot
    A4D258, A7VJ95, A8K0E6, D3DVM9, O00427, O00701, O75222, Q13322, Q92606, Q92907, Q92948
    Related
    ENSP00000381793.2, ENST00000398812.6
  5. XM_017012034.2XP_016867523.1  growth factor receptor-bound protein 10 isoform X5

  6. XM_047420252.1XP_047276208.1  growth factor receptor-bound protein 10 isoform X7

  7. XM_047420244.1XP_047276200.1  growth factor receptor-bound protein 10 isoform X10

  8. XM_047420240.1XP_047276196.1  growth factor receptor-bound protein 10 isoform X6

  9. XM_024446726.2XP_024302494.1  growth factor receptor-bound protein 10 isoform X3

    Conserved Domains (4) summary
    cd01787
    Location:250331
    GRB7_RA; RA (RAS-associated like) domain of Grb7
    cd10415
    Location:570677
    SH2_Grb10; Src homology 2 (SH2) domain found in the growth factor receptor bound, subclass 10 (Grb10) proteins
    cd01259
    Location:369491
    PH_APBB1IP; Amyloid beta (A4) Precursor protein-Binding, family B, member 1 Interacting Protein pleckstrin homology (PH) domain
    pfam08947
    Location:509550
    BPS; BPS (Between PH and SH2)
  10. XM_017012030.3XP_016867519.1  growth factor receptor-bound protein 10 isoform X2

  11. XM_017012031.3XP_016867520.1  growth factor receptor-bound protein 10 isoform X4

  12. XM_017012029.3XP_016867518.1  growth factor receptor-bound protein 10 isoform X1

  13. XM_047420253.1XP_047276209.1  growth factor receptor-bound protein 10 isoform X7

  14. XM_047420254.1XP_047276210.1  growth factor receptor-bound protein 10 isoform X7

  15. XM_047420255.1XP_047276211.1  growth factor receptor-bound protein 10 isoform X7

  16. XM_047420238.1XP_047276194.1  growth factor receptor-bound protein 10 isoform X6

  17. XM_047420232.1XP_047276188.1  growth factor receptor-bound protein 10 isoform X5

  18. XM_047420250.1XP_047276206.1  growth factor receptor-bound protein 10 isoform X11

  19. XM_024446729.2XP_024302497.1  growth factor receptor-bound protein 10 isoform X11

    Conserved Domains (4) summary
    cd01787
    Location:154235
    GRB7_RA; RA (RAS-associated like) domain of Grb7
    cd10415
    Location:474581
    SH2_Grb10; Src homology 2 (SH2) domain found in the growth factor receptor bound, subclass 10 (Grb10) proteins
    cd01259
    Location:273395
    PH_APBB1IP; Amyloid beta (A4) Precursor protein-Binding, family B, member 1 Interacting Protein pleckstrin homology (PH) domain
    pfam08947
    Location:413454
    BPS; BPS (Between PH and SH2)
  20. XM_047420249.1XP_047276205.1  growth factor receptor-bound protein 10 isoform X11

  21. XM_047420247.1XP_047276203.1  growth factor receptor-bound protein 10 isoform X11

  22. XM_047420236.1XP_047276192.1  growth factor receptor-bound protein 10 isoform X6

  23. XM_047420248.1XP_047276204.1  growth factor receptor-bound protein 10 isoform X11

  24. XM_047420246.1XP_047276202.1  growth factor receptor-bound protein 10 isoform X11

  25. XM_047420235.1XP_047276191.1  growth factor receptor-bound protein 10 isoform X6

  26. XM_047420234.1XP_047276190.1  growth factor receptor-bound protein 10 isoform X6

  27. XM_047420245.1XP_047276201.1  growth factor receptor-bound protein 10 isoform X11

  28. XM_047420251.1XP_047276207.1  growth factor receptor-bound protein 10 isoform X11

  29. XM_047420237.1XP_047276193.1  growth factor receptor-bound protein 10 isoform X6

  30. XM_017012058.1XP_016867547.1  growth factor receptor-bound protein 10 isoform X11

    Conserved Domains (4) summary
    cd01787
    Location:154235
    GRB7_RA; RA (RAS-associated like) domain of Grb7
    cd10415
    Location:474581
    SH2_Grb10; Src homology 2 (SH2) domain found in the growth factor receptor bound, subclass 10 (Grb10) proteins
    cd01259
    Location:273395
    PH_APBB1IP; Amyloid beta (A4) Precursor protein-Binding, family B, member 1 Interacting Protein pleckstrin homology (PH) domain
    pfam08947
    Location:413454
    BPS; BPS (Between PH and SH2)
  31. XM_017012062.3XP_016867551.1  growth factor receptor-bound protein 10 isoform X11

    Conserved Domains (4) summary
    cd01787
    Location:154235
    GRB7_RA; RA (RAS-associated like) domain of Grb7
    cd10415
    Location:474581
    SH2_Grb10; Src homology 2 (SH2) domain found in the growth factor receptor bound, subclass 10 (Grb10) proteins
    cd01259
    Location:273395
    PH_APBB1IP; Amyloid beta (A4) Precursor protein-Binding, family B, member 1 Interacting Protein pleckstrin homology (PH) domain
    pfam08947
    Location:413454
    BPS; BPS (Between PH and SH2)
  32. XM_017012045.1XP_016867534.1  growth factor receptor-bound protein 10 isoform X7

    UniProtKB/Swiss-Prot
    Q13322
    Related
    ENSP00000385189.1, ENST00000402578.5
    Conserved Domains (4) summary
    cd10415
    Location:429536
    SH2_Grb10; Src homology 2 (SH2) domain found in the growth factor receptor bound, subclass 10 (Grb10) proteins
    cd01259
    Location:228350
    PH_APBB1IP; Amyloid beta (A4) Precursor protein-Binding, family B, member 1 Interacting Protein pleckstrin homology (PH) domain
    cd16141
    Location:108199
    RA_GRB10; Ras-associating (RA) domain found in growth factor receptor-bound (Grb) protein 10
    pfam08947
    Location:368409
    BPS; BPS (Between PH and SH2)
  33. XM_047420242.1XP_047276198.1  growth factor receptor-bound protein 10 isoform X9

  34. XM_047420256.1XP_047276212.1  growth factor receptor-bound protein 10 isoform X12

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060931.1 Alternate T2T-CHM13v2.0

    Range
    50751214..50954643 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054357968.1XP_054213943.1  growth factor receptor-bound protein 10 isoform X11

  2. XM_054357966.1XP_054213941.1  growth factor receptor-bound protein 10 isoform X10

  3. XM_054357957.1XP_054213932.1  growth factor receptor-bound protein 10 isoform X6

  4. XM_054357964.1XP_054213939.1  growth factor receptor-bound protein 10 isoform X8

    UniProtKB/Swiss-Prot
    A4D258, A7VJ95, A8K0E6, D3DVM9, O00427, O00701, O75222, Q13322, Q92606, Q92907, Q92948
  5. XM_054357956.1XP_054213931.1  growth factor receptor-bound protein 10 isoform X5

  6. XM_054357979.1XP_054213954.1  growth factor receptor-bound protein 10 isoform X7

  7. XM_054357953.1XP_054213928.1  growth factor receptor-bound protein 10 isoform X3

  8. XM_054357967.1XP_054213942.1  growth factor receptor-bound protein 10 isoform X10

  9. XM_054357952.1XP_054213927.1  growth factor receptor-bound protein 10 isoform X2

  10. XM_054357954.1XP_054213929.1  growth factor receptor-bound protein 10 isoform X4

  11. XM_054357951.1XP_054213926.1  growth factor receptor-bound protein 10 isoform X1

  12. XM_054357980.1XP_054213955.1  growth factor receptor-bound protein 10 isoform X7

  13. XM_054357981.1XP_054213956.1  growth factor receptor-bound protein 10 isoform X7

  14. XM_054357962.1XP_054213937.1  growth factor receptor-bound protein 10 isoform X6

  15. XM_054357955.1XP_054213930.1  growth factor receptor-bound protein 10 isoform X5

  16. XM_054357976.1XP_054213951.1  growth factor receptor-bound protein 10 isoform X11

  17. XM_054357973.1XP_054213948.1  growth factor receptor-bound protein 10 isoform X11

  18. XM_054357975.1XP_054213950.1  growth factor receptor-bound protein 10 isoform X11

  19. XM_054357971.1XP_054213946.1  growth factor receptor-bound protein 10 isoform X11

  20. XM_054357960.1XP_054213935.1  growth factor receptor-bound protein 10 isoform X6

  21. XM_054357974.1XP_054213949.1  growth factor receptor-bound protein 10 isoform X11

  22. XM_054357970.1XP_054213945.1  growth factor receptor-bound protein 10 isoform X11

  23. XM_054357959.1XP_054213934.1  growth factor receptor-bound protein 10 isoform X6

  24. XM_054357958.1XP_054213933.1  growth factor receptor-bound protein 10 isoform X6

  25. XM_054357969.1XP_054213944.1  growth factor receptor-bound protein 10 isoform X11

  26. XM_054357977.1XP_054213952.1  growth factor receptor-bound protein 10 isoform X11

  27. XM_054357961.1XP_054213936.1  growth factor receptor-bound protein 10 isoform X6

  28. XM_054357972.1XP_054213947.1  growth factor receptor-bound protein 10 isoform X11

  29. XM_054357978.1XP_054213953.1  growth factor receptor-bound protein 10 isoform X11

  30. XM_054357963.1XP_054213938.1  growth factor receptor-bound protein 10 isoform X7

  31. XM_054357965.1XP_054213940.1  growth factor receptor-bound protein 10 isoform X9

  32. XM_054357982.1XP_054213957.1  growth factor receptor-bound protein 10 isoform X12

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