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DppIII Dipeptidyl aminopeptidase III [ Drosophila melanogaster (fruit fly) ]

Gene ID: 40996, updated on 9-Dec-2024

Summary

Official Symbol
DppIIIprovided by FlyBase
Official Full Name
Dipeptidyl aminopeptidase IIIprovided by FlyBase
Primary source
FLYBASE:FBgn0037580
Locus tag
Dmel_CG7415
See related
AllianceGenome:FB:FBgn0037580
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG7415; Dmel\CG7415; DPP; DPP III
Summary
Enables dipeptidyl-peptidase activity. Involved in proteolysis. Located in cytosol and membrane. Is expressed in several structures, including adult head; adult heart; embryonic/larval midgut; embryonic/larval midgut primordium; and larval ventral nerve cord. Orthologous to human DPP3 (dipeptidyl peptidase 3). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
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Genomic context

See DppIII in Genome Data Viewer
Location:
84F13-84F13; 3-48 cM
Exon count:
4
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (8344400..8347465)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (4170122..4173187)

Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene ADP ribosylation factor-like 2 Neighboring gene Polynucleotide kinase 3'-phosphatase Neighboring gene Cytochrome c oxidase subunit 7A-like Neighboring gene uncharacterized protein Neighboring gene mir-9380 stem loop Neighboring gene Autophagy-related 13

Genomic regions, transcripts, and products

Interactions

General gene information

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables dipeptidyl-peptidase activity  
enables dipeptidyl-peptidase activity PubMed 
enables dipeptidyl-peptidase activity  
enables metalloexopeptidase activity  
Process Evidence Code Pubs
involved_in proteolysis PubMed 
involved_in proteolysis  
Component Evidence Code Pubs
is_active_in cytoplasm  
located_in cytoplasm  
located_in cytosol PubMed 
located_in membrane PubMed 

General protein information

Preferred Names
dipeptidyl aminopeptidase III
Names
CG7415-PB
CG7415-PC
Dipeptidyl-peptidase III
DppIII-PB
DppIII-PC
dipeptidyl aminopeptidase
NP_731237.1
NP_731238.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033777.3 Reference assembly

    Range
    8344400..8347465
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_169217.3NP_731237.1  dipeptidyl aminopeptidase III, isoform C [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_731237.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q8IHE9, Q961F1, Q9VHR8
    UniProtKB/TrEMBL
    Q6BCZ0
    Related
    FBpp0081331
    Conserved Domains (1) summary
    pfam03571
    Location:211760
    Peptidase_M49; Peptidase family M49
  2. NM_169218.3NP_731238.1  dipeptidyl aminopeptidase III, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_731238.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q6BCZ0
    Related
    FBpp0081330
    Conserved Domains (1) summary
    pfam03571
    Location:148697
    Peptidase_M49; Peptidase family M49
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