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rhocb ras homolog family member Cb [ Danio rerio (zebrafish) ]

Gene ID: 436718, updated on 9-Dec-2024

Summary

Official Symbol
rhocbprovided by ZNC
Official Full Name
ras homolog family member Cbprovided by ZNC
Primary source
ZFIN:ZDB-GENE-040718-144
See related
Ensembl:ENSDARG00000018328 AllianceGenome:ZFIN:ZDB-GENE-040718-144
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
rhoad; zgc:92350
Summary
Predicted to enable GTP binding activity; GTPase activity; and protein kinase binding activity. Predicted to be involved in several processes, including actin filament organization; skeletal muscle satellite cell migration; and wound healing, spreading of cells. Predicted to act upstream of or within small GTPase-mediated signal transduction. Predicted to be located in membrane. Predicted to be active in cytosol and plasma membrane. Is expressed in dorsal aorta; intersegmental vessel; neural tube; and posterior cardinal vein. Orthologous to human RHOC (ras homolog family member C). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
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Genomic context

See rhocb in Genome Data Viewer
Location:
chromosome: 8
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 8 NC_007119.7 (27555372..27624329)
105 previous assembly GRCz10 (GCF_000002035.5) 8 NC_007119.6 (27536233..27605190)

Chromosome 8 - NC_007119.7Genomic Context describing neighboring genes Neighboring gene TAFA chemokine like family member 3b Neighboring gene uncharacterized LOC101886754 Neighboring gene protein Hook homolog 1-like Neighboring gene uncharacterized LOC137496299 Neighboring gene uncharacterized LOC110440015 Neighboring gene Mov10 RNA helicase b, tandem duplicate 2 Neighboring gene Mov10 RNA helicase b, tandem duplicate 1

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Pathways from PubChem

General gene information

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables GTP binding  
enables GTP binding  
enables GTPase activity  
enables GTPase activity  
enables nucleotide binding  
enables protein kinase binding  
Process Evidence Code Pubs
involved_in actin filament organization  
involved_in cell migration  
involved_in mitotic cytokinesis  
involved_in regulation of actin cytoskeleton organization  
involved_in signal transduction  
involved_in skeletal muscle satellite cell migration  
acts_upstream_of_or_within small GTPase-mediated signal transduction  
involved_in wound healing, spreading of cells  
Component Evidence Code Pubs
is_active_in cytosol  
located_in membrane  
is_active_in plasma membrane  
located_in plasma membrane  

General protein information

Preferred Names
rho-related GTP-binding protein RhoA-D
Names
ras homolog gene family, member Ad
rho-related GTP-binding protein RhoC
NP_001002445.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001002445.1NP_001002445.1  rho-related GTP-binding protein RhoA-D

    See identical proteins and their annotated locations for NP_001002445.1

    Status: PROVISIONAL

    Source sequence(s)
    BC076026
    UniProtKB/Swiss-Prot
    Q6DHE8
    Related
    ENSDARP00000002761.7, ENSDART00000016696.8
    Conserved Domains (2) summary
    smart00174
    Location:8180
    RHO; Rho (Ras homology) subfamily of Ras-like small GTPases
    cd01870
    Location:5179
    RhoA_like; Ras homology family A (RhoA)-like includes RhoA, RhoB and RhoC

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007119.7 Reference GRCz11 Primary Assembly

    Range
    27555372..27624329
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCz11 ALT_DRER_TU_1

Genomic

  1. NW_018394727.1 Reference GRCz11 ALT_DRER_TU_1

    Range
    552139..593364
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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