U.S. flag

An official website of the United States government

Links from GEO Profiles

    • Showing Current items.

    peli-1 Protein pellino [ Caenorhabditis elegans ]

    Gene ID: 178959, updated on 9-Dec-2024

    Summary

    Official Symbol
    peli-1
    Official Full Name
    Protein pellino
    Primary source
    WormBase:WBGene00017766
    Locus tag
    CELE_F25B4.2
    See related
    AllianceGenome:WB:WBGene00017766
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in protein polyubiquitination. Is expressed in several structures, including body wall musculature; intestine; nervous system; pharynx; and reproductive system. Human ortholog(s) of this gene implicated in colorectal cancer. Orthologous to several human genes including PELI2 (pellino E3 ubiquitin protein ligase family member 2) and PELI3 (pellino E3 ubiquitin protein ligase family member 3). [provided by Alliance of Genome Resources, Dec 2024]
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See peli-1 in Genome Data Viewer
    Location:
    chromosome: V
    Exon count:
    8
    Sequence:
    Chromosome: V; NC_003283.11 (5709418..5712331)

    Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene C-type lectin domain-containing protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Aminomethyltransferase Neighboring gene Neuropeptide CCHamide-1 Neighboring gene ncRNA

    Interactions

    General gene information

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables ubiquitin protein ligase activity  
    enables ubiquitin protein ligase activity  
    Process Evidence Code Pubs
    involved_in protein polyubiquitination  
    involved_in protein polyubiquitination  
    involved_in regulation of Toll signaling pathway  

    General protein information

    Preferred Names
    Protein pellino
    NP_001370430.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003283.11 Reference assembly

      Range
      5709418..5712331
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001383308.2NP_001370430.1  Protein pellino [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q22967, Q9NAP3
      Conserved Domains (1) summary
      pfam04710
      Location:17445
      Pellino
    External link. Please review our privacy policy.