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    GLR3.5 glutamate receptor 3.5 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 817800, updated on 18-Sep-2024

    Summary

    Official Symbol
    GLR3.5
    Official Full Name
    glutamate receptor 3.5
    Primary source
    TAIR:AT2G32390
    Locus tag
    AT2G32390
    See related
    Araport:AT2G32390
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ATGLR3.5; GLR6; glutamate receptor 3.5; glutamate receptor 3.5; T32F6.9; T32F6_9
    Summary
    Encodes a ionotropic glutamate receptor ortholog, a member of a putative ligand-gated ion channel subunit family
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    Genomic context

    See GLR3.5 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    6
    Sequence:
    Chromosome: 2; NC_003071.7 (13748280..13752281, complement)

    Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene homeodomain GLABROUS 3 Neighboring gene Transmembrane protein 97, Putative Neighboring gene glutamate receptor 5 Neighboring gene AXR1-like protein Neighboring gene Polynucleotidyl transferase, ribonuclease H fold protein with HRDC domain-containing protein Neighboring gene Galactosyltransferase family protein

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    General gene information

    NM_001036387.2
    NM_001336393.1
    NM_128798.1

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables G protein-coupled receptor activity  
    enables calcium channel activity  
    enables glutamate receptor activity  
    enables intracellularly ligand-gated monoatomic ion channel activity  
    enables ligand-gated monoatomic ion channel activity  
    enables monoatomic ion channel activity PubMed 
    Component Evidence Code Pubs
    located_in chloroplast PubMed 
    located_in chloroplast  
    located_in extracellular region  
    located_in mitochondrion PubMed 
    located_in plasma membrane  
    located_in plasma membrane  

    General protein information

    Preferred Names
    glutamate receptor 3.5
    NP_001031464.1
    • glutamate receptor 3.5 (GLR3.5); FUNCTIONS IN: intracellular ligand-gated ion channel activity; INVOLVED IN: cellular calcium ion homeostasis, response to light stimulus; LOCATED IN: integral to membrane, membrane; EXPRESSED IN: 20 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Extracellular solute-binding protein, family 3 (InterPro:IPR001638), Ionotropic glutamate receptor (InterPro:IPR001320), Glutamate receptor-related (InterPro:IPR015683), Extracellular ligand-binding receptor (InterPro:IPR001828), GPCR, family 3 (InterPro:IPR000337), Ionotropic glutamate-like receptor, plant (InterPro:IPR017103); BEST Arabidopsis thaliana protein match is: glutamate receptor 3.4 (TAIR:AT1G05200.2); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).
    NP_001318335.1
    • glutamate receptor 3.5 (GLR3.5); FUNCTIONS IN: intracellular ligand-gated ion channel activity; INVOLVED IN: cellular calcium ion homeostasis, response to light stimulus; LOCATED IN: integral to membrane, membrane; EXPRESSED IN: 20 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Extracellular solute-binding protein, family 3 (InterPro:IPR001638), Ionotropic glutamate receptor (InterPro:IPR001320), GPCR, family 3, gamma-aminobutyric acid receptor, type B (InterPro:IPR002455), Extracellular ligand-binding receptor (InterPro:IPR001828), Glutamate receptor-related (InterPro:IPR015683), Ionotropic glutamate-like receptor, plant (InterPro:IPR017103); BEST Arabidopsis thaliana protein match is: glutamate receptor 3.4 (TAIR:AT1G05200.2).
    NP_565743.1
    • glutamate receptor 3.5 (GLR3.5); FUNCTIONS IN: intracellular ligand-gated ion channel activity; INVOLVED IN: cellular calcium ion homeostasis, response to light stimulus; LOCATED IN: integral to membrane, membrane; EXPRESSED IN: 20 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Extracellular solute-binding protein, family 3 (InterPro:IPR001638), Ionotropic glutamate receptor (InterPro:IPR001320), Glutamate receptor-related (InterPro:IPR015683), Extracellular ligand-binding receptor (InterPro:IPR001828), GPCR, family 3 (InterPro:IPR000337), Ionotropic glutamate-like receptor, plant (InterPro:IPR017103); BEST Arabidopsis thaliana protein match is: glutamate receptor 3.4 (TAIR:AT1G05200.2); Has 5516 Blast hits to 5369 proteins in 333 species: Archae - 14; Bacteria - 348; Metazoa - 4290; Fungi - 0; Plants - 640; Viruses - 0; Other Eukaryotes - 224 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003071.7 Reference assembly

      Range
      13748280..13752281 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001336391.1NP_001324013.1  glutamate receptor 3.5 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      F4ITQ1, Q9SW97, Q9ZV67
      UniProtKB/TrEMBL
      A0A654EZL4
    2. NM_001336390.1NP_001324012.1  glutamate receptor 3.5 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178VXC7, F4ITQ0
    3. NM_001336389.1NP_001318335.1  glutamate receptor 3.5 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178VXC7, F4ITQ0
    4. NM_001336392.1NP_001324010.1  glutamate receptor 3.5 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178VXC7, A0A1P8AYW8
    5. NM_001036387.2NP_001031464.1  glutamate receptor 3.5 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001031464.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      F4ITQ2, Q6RKN4
      Conserved Domains (5) summary
      cd06366
      Location:1340
      PBP1_GABAb_receptor; Ligand-binding domain of GABAb receptors, which are metabotropic transmembrane receptors for gamma-aminobutyric acid (GABA)
      COG0834
      Location:398511
      HisJ; ABC-type amino acid transport/signal transduction system, periplasmic component/domain [Amino acid transport and metabolism, Signal transduction mechanisms]
      cd13686
      Location:383726
      GluR_Plant; Plant glutamate receptor domain; the type 2 periplasmic binding protein fold
      pfam00060
      Location:506758
      Lig_chan; Ligand-gated ion channel
      pfam01094
      Location:1322
      ANF_receptor; Receptor family ligand binding region
    6. NM_128798.1NP_565743.1  glutamate receptor 3.5 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_565743.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q6RKN4
      Conserved Domains (5) summary
      cd06366
      Location:49384
      PBP1_GABAb_receptor; Ligand-binding domain of GABAb receptors, which are metabotropic transmembrane receptors for gamma-aminobutyric acid (GABA)
      COG0834
      Location:442555
      HisJ; ABC-type amino acid transport/signal transduction system, periplasmic component/domain [Amino acid transport and metabolism, Signal transduction mechanisms]
      cd13686
      Location:427770
      GluR_Plant; Plant glutamate receptor domain; the type 2 periplasmic binding protein fold
      pfam00060
      Location:550802
      Lig_chan; Ligand-gated ion channel
      pfam01094
      Location:49366
      ANF_receptor; Receptor family ligand binding region
    7. NM_001336393.1NP_001324011.1  glutamate receptor 3.5 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178VXC7, A0A1P8AYR0
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