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    RDR6 RNA-dependent RNA polymerase 6 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 824112, updated on 18-Sep-2024

    Summary

    Official Symbol
    RDR6
    Official Full Name
    RNA-dependent RNA polymerase 6
    Primary source
    TAIR:AT3G49500
    Locus tag
    AT3G49500
    See related
    Araport:AT3G49500
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    AtRDR6; RNA-dependent RNA polymerase 6; SDE1; SGS2; SILENCING DEFECTIVE 1; SUPPRESSOR OF GENE SILENCING 2
    Summary
    Encodes RNA-dependent RNA polymerase. Involved in trans-acting siRNA and other siRNA biogenesis. Required for post-transcriptional gene silencing and natural virus resistance.
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    Genomic context

    See RDR6 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    3
    Sequence:
    Chromosome: 3; NC_003074.8 (18348974..18353673, complement)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene nascent polypeptide-associated complex subunit alpha-like protein 2 Neighboring gene F-box/FBD/LRR protein Neighboring gene uncharacterized protein Neighboring gene F-box family protein Neighboring gene F-box and associated interaction domains-containing protein

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Interactions

    General gene information

    NM_001339424.1
    NM_001339425.1
    NM_001339426.1
    NM_114810.3

    Gene Ontology Provided by TAIR

    Component Evidence Code Pubs
    located_in nucleus PubMed 
    located_in nucleus  

    General protein information

    Preferred Names
    RNA-dependent RNA polymerase 6
    NP_190519.1
    • RNA-dependent RNA polymerase 6 (RDR6); CONTAINS InterPro DOMAIN/s: RNA-dependent RNA polymerase, eukaryotic-type (InterPro:IPR007855); BEST Arabidopsis thaliana protein match is: RNA-dependent RNA polymerase 1 (TAIR:AT1G14790.1); Has 633 Blast hits to 609 proteins in 113 species: Archae - 0; Bacteria - 0; Metazoa - 73; Fungi - 284; Plants - 204; Viruses - 2; Other Eukaryotes - 70 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      18348974..18353673 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001339423.1NP_001327617.1  RNA-dependent RNA polymerase 6 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      A0A1I9LSW2, Q9LKP0, Q9SG02
      UniProtKB/TrEMBL
      A0A7G2ETS9
    2. NM_114810.3NP_190519.1  RNA-dependent RNA polymerase 6 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_190519.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      A0A1I9LSW2, Q9LKP0, Q9SG02
      UniProtKB/TrEMBL
      A0A7G2ETS9
      Conserved Domains (2) summary
      pfam05183
      Location:424940
      RdRP; RNA dependent RNA polymerase
      cl17169
      Location:68112
      RRM_SF; RNA recognition motif (RRM) superfamily
    3. NM_001339426.1NP_001327620.1  RNA-dependent RNA polymerase 6 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      A0A1I9LSW2, Q9LKP0, Q9SG02
      UniProtKB/TrEMBL
      A0A7G2ETS9
    4. NM_001339425.1NP_001327619.1  RNA-dependent RNA polymerase 6 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      A0A1I9LSW2, Q9LKP0, Q9SG02
      UniProtKB/TrEMBL
      A0A7G2ETS9
    5. NM_001339424.1NP_001327618.1  RNA-dependent RNA polymerase 6 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      A0A1I9LSW2, Q9LKP0, Q9SG02
      UniProtKB/TrEMBL
      A0A7G2ETS9
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