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Ss18l1 SS18L1 subunit of BAF chromatin remodeling complex [ Rattus norvegicus (Norway rat) ]

Gene ID: 192352, updated on 9-Dec-2024

Summary

Official Symbol
Ss18l1provided by RGD
Official Full Name
SS18L1 subunit of BAF chromatin remodeling complexprovided by RGD
Primary source
RGD:621847
See related
EnsemblRapid:ENSRNOG00000060010 AllianceGenome:RGD:621847
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
CREST
Summary
Predicted to enable transcription coactivator activity. Involved in positive regulation of DNA-templated transcription and regulation of dendrite development. Located in nuclear body. Orthologous to human SS18L1 (SS18L1 subunit of BAF chromatin remodeling complex). [provided by Alliance of Genome Resources, Dec 2024]
Expression
Biased expression in Kidney (RPKM 116.0), Brain (RPKM 115.7) and 9 other tissues See more
Orthologs
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Genomic context

See Ss18l1 in Genome Data Viewer
Location:
3q43
Exon count:
12
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 3 NC_086021.1 (187521616..187542873)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 3 NC_051338.1 (167143730..167165253)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 3 NC_005102.4 (175426754..175445222)

Chromosome 3 - NC_086021.1Genomic Context describing neighboring genes Neighboring gene LSM family member 14B Neighboring gene proteasome 20S subunit alpha 7 Neighboring gene mitochondrial ribosome-associated GTPase 2 Neighboring gene histamine receptor H3

Genomic regions, transcripts, and products

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

General gene information

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables protein binding PubMed 
enables transcription coactivator activity  
Component Evidence Code Pubs
located_in condensed chromosome, centromeric region  
located_in cytosol  
located_in cytosol  
located_in kinetochore  
located_in kinetochore  
part_of nBAF complex  
part_of nBAF complex  
located_in nuclear body PubMed 
located_in nucleoplasm  
located_in nucleoplasm  
is_active_in nucleus  
located_in nucleus PubMed 

General protein information

Preferred Names
calcium-responsive transcription coactivator
Names
SS18-like protein 1
SS18L1, nBAF chromatin remodeling complex subunit
calcium-responsive transactivator
synovial sarcoma translocation gene on chromosome 18-like 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_138918.2NP_620273.2  calcium-responsive transcription coactivator

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000003
    UniProtKB/Swiss-Prot
    Q91XJ0
    UniProtKB/TrEMBL
    A0A8I5ZQS4, A6KMC5
    Related
    ENSRNOP00000080662.1, ENSRNOT00000111398.2
    Conserved Domains (1) summary
    pfam05030
    Location:1473
    SSXT; SSXT protein (N-terminal region)

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086021.1 Reference GRCr8

    Range
    187521616..187542873
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039104228.2XP_038960156.2  calcium-responsive transcription coactivator isoform X1

    UniProtKB/Swiss-Prot
    Q91XJ0
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