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Btbd2 BTB domain containing 2 [ Mus musculus (house mouse) ]

Gene ID: 208198, updated on 9-Dec-2024

Summary

Official Symbol
Btbd2provided by MGI
Official Full Name
BTB domain containing 2provided by MGI
Primary source
MGI:MGI:1933831
See related
Ensembl:ENSMUSG00000003344 AllianceGenome:MGI:1933831
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
2610037C03Rik; 4930512K17Rik
Summary
Predicted to be involved in neurogenesis. Predicted to be active in P-body and cytosol. Orthologous to human BTBD2 (BTB domain containing 2). [provided by Alliance of Genome Resources, Dec 2024]
Expression
Ubiquitous expression in adrenal adult (RPKM 45.6), ovary adult (RPKM 43.7) and 28 other tissues See more
Orthologs
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Genomic context

See Btbd2 in Genome Data Viewer
Location:
10 C1; 10 39.72 cM
Exon count:
9
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 10 NC_000076.7 (80478457..80492328, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 10 NC_000076.6 (80642623..80656494, complement)

Chromosome 10 - NC_000076.7Genomic Context describing neighboring genes Neighboring gene secretory carrier membrane protein 4 Neighboring gene predicted gene, 31298 Neighboring gene casein kinase 1, gamma 2 Neighboring gene predicted gene, 51810 Neighboring gene STARR-positive B cell enhancer ABC_E3899 Neighboring gene MAP kinase-interacting serine/threonine kinase 2 Neighboring gene CapStarr-seq enhancer MGSCv37_chr10:80141015-80141203 Neighboring gene MOB kinase activator 3A Neighboring gene STARR-positive B cell enhancer ABC_E6884

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (4) 

Interactions

General gene information

Gene Ontology Provided by MGI

Process Evidence Code Pubs
involved_in neurogenesis  
Component Evidence Code Pubs
is_active_in P-body  
located_in P-body  
is_active_in cytosol  

General protein information

Preferred Names
BTB/POZ domain-containing protein 2
Names
BTB (POZ) domain containing 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001379084.1NP_001366013.1  BTB/POZ domain-containing protein 2 isoform 1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
    Source sequence(s)
    AC152410
    Conserved Domains (3) summary
    cd18281
    Location:78204
    BTB_POZ_BTBD1_2; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in BTB/POZ domain-containing proteins, BTBD1 and BTBD2
    cd18523
    Location:200305
    BACK_BTBD2; BACK (BTB and C-terminal Kelch) domain found in BTB/POZ domain-containing protein 2 (BTBD2)
    pfam08005
    Location:364513
    PHR; PHR domain
  2. NM_145361.3NP_663336.3  BTB/POZ domain-containing protein 2 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC152410
    Consensus CDS
    CCDS48639.1
    UniProtKB/TrEMBL
    E9PY28
    Related
    ENSMUSP00000120751.2, ENSMUST00000126980.8
    Conserved Domains (3) summary
    cd18281
    Location:78204
    BTB_POZ_BTBD1_2; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in BTB/POZ domain-containing proteins, BTBD1 and BTBD2
    cd18523
    Location:200305
    BACK_BTBD2; BACK (BTB and C-terminal Kelch) domain found in BTB/POZ domain-containing protein 2 (BTBD2)
    pfam08005
    Location:358507
    PHR; PHR domain

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000076.7 Reference GRCm39 C57BL/6J

    Range
    80478457..80492328 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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