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    Myg1 melanocyte proliferating gene 1 [ Mus musculus (house mouse) ]

    Gene ID: 60315, updated on 9-Dec-2024

    Summary

    Official Symbol
    Myg1provided by MGI
    Official Full Name
    melanocyte proliferating gene 1provided by MGI
    Primary source
    MGI:MGI:1929864
    See related
    Ensembl:ENSMUSG00000001285 AllianceGenome:MGI:1929864
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Gamm1; 0610023A07Rik; 2810433J21Rik; 5830429P19Rik
    Summary
    Predicted to enable nuclease activity. Acts upstream of or within locomotory exploration behavior. Predicted to be located in mitochondrion and nucleoplasm. Predicted to be active in cytoplasm and nucleus. Is expressed in several structures, including alimentary system; brain; eye; hemolymphoid system gland; and male reproductive gland or organ. Orthologous to human MYG1 (MYG1 exonuclease). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Ubiquitous expression in CNS E11.5 (RPKM 22.9), adrenal adult (RPKM 22.3) and 28 other tissues See more
    Orthologs
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    Genomic context

    See Myg1 in Genome Data Viewer
    Location:
    15 F3; 15 57.49 cM
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 15 NC_000081.7 (102240144..102246574)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 15 NC_000081.6 (102331709..102338139)

    Chromosome 15 - NC_000081.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E5520 Neighboring gene extra spindle pole bodies 1, separase Neighboring gene STARR-positive B cell enhancer ABC_E7421 Neighboring gene STARR-positive B cell enhancer ABC_E7422 Neighboring gene prefoldin 5 Neighboring gene microRNA 12187 Neighboring gene achalasia, adrenocortical insufficiency, alacrimia Neighboring gene STARR-seq mESC enhancer starr_39832 Neighboring gene predicted gene, 36246

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Interactions

    General gene information

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables 3'-5'-RNA exonuclease activity  
    enables molecular_function  
    Component Evidence Code Pubs
    is_active_in cytoplasm  
    located_in mitochondrial matrix  
    located_in mitochondrion  
    located_in mitochondrion  
    located_in nucleolus  
    located_in nucleoplasm  
    located_in nucleoplasm  
    is_active_in nucleus  
    located_in nucleus  
    located_in nucleus  

    General protein information

    Preferred Names
    MYG1 exonuclease
    Names
    UPF0160 protein MYG1, mitochondrial
    protein Gamm1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_021713.2NP_068359.1  MYG1 exonuclease precursor

      See identical proteins and their annotated locations for NP_068359.1

      Status: VALIDATED

      Source sequence(s)
      AF289484, BU851558, CJ180315
      Consensus CDS
      CCDS27879.1
      UniProtKB/Swiss-Prot
      Q9CYX0, Q9JK81
      UniProtKB/TrEMBL
      Q8R038
      Related
      ENSMUSP00000109312.3, ENSMUST00000113682.9
      Conserved Domains (1) summary
      pfam03690
      Location:45365
      UPF0160; uncharacterized protein family (UPF0160)

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000081.7 Reference GRCm39 C57BL/6J

      Range
      102240144..102246574
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_030248679.1XP_030104539.1  MYG1 exonuclease isoform X1

      Conserved Domains (1) summary
      pfam03690
      Location:10251
      UPF0160; Uncharacterized protein family (UPF0160)
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