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Nkain1 Na+/K+ transporting ATPase interacting 1 [ Mus musculus (house mouse) ]

Gene ID: 67149, updated on 9-Dec-2024

Summary

Official Symbol
Nkain1provided by MGI
Official Full Name
Na+/K+ transporting ATPase interacting 1provided by MGI
Primary source
MGI:MGI:1914399
See related
Ensembl:ENSMUSG00000078532 AllianceGenome:MGI:1914399
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
2610200G18Rik; 2810426C15Rik
Summary
Enables ATPase binding activity. Predicted to be involved in regulation of sodium ion transport. Located in plasma membrane. Is expressed in several structures, including central nervous system; lung; metanephros; and retina layer. Orthologous to human NKAIN1 (sodium/potassium transporting ATPase interacting 1). [provided by Alliance of Genome Resources, Dec 2024]
Expression
Broad expression in whole brain E14.5 (RPKM 62.7), CNS E18 (RPKM 54.6) and 17 other tissues See more
Orthologs
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Genomic context

See Nkain1 in Genome Data Viewer
Location:
4 D2.2; 4 63.43 cM
Exon count:
9
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (130297176..130341115)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (130530131..130574216, complement)

Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene zinc finger, CCHC domain containing 17 Neighboring gene predicted gene, 35074 Neighboring gene STARR-positive B cell enhancer ABC_E425 Neighboring gene small nuclear ribonucleoprotein 40 (U5) Neighboring gene STARR-seq mESC enhancer starr_11526 Neighboring gene STARR-seq mESC enhancer starr_11530 Neighboring gene predicted gene, 53228 Neighboring gene STARR-seq mESC enhancer starr_11531 Neighboring gene STARR-seq mESC enhancer starr_11533 Neighboring gene pumilio RNA-binding family member 1 Neighboring gene small nucleolar RNA, C/D box 85

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Gene trapped (1) 

General gene information

Clone Names

  • MGC144417

Gene Ontology Provided by MGI

Component Evidence Code Pubs
located_in plasma membrane PubMed 

General protein information

Preferred Names
sodium/potassium-transporting ATPase subunit beta-1-interacting protein 1
Names
Na(+)/K(+)-transporting ATPase subunit beta-1-interacting protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001427131.1NP_001414060.1  sodium/potassium-transporting ATPase subunit beta-1-interacting protein 1 isoform 2

    Status: VALIDATED

    Source sequence(s)
    FO907130, FQ976844, MH423692
  2. NM_001427132.1NP_001414061.1  sodium/potassium-transporting ATPase subunit beta-1-interacting protein 1 isoform 3

    Status: VALIDATED

    Source sequence(s)
    FO907130, FQ976844, MH423692
  3. NM_001427133.1NP_001414062.1  sodium/potassium-transporting ATPase subunit beta-1-interacting protein 1 isoform 4

    Status: VALIDATED

    Source sequence(s)
    FO907130, FQ976844, MH423692
  4. NM_001427134.1NP_001414063.1  sodium/potassium-transporting ATPase subunit beta-1-interacting protein 1 isoform 5

    Status: VALIDATED

    Source sequence(s)
    FO907130, FQ976844, MH423692
  5. NM_025998.5NP_080274.2  sodium/potassium-transporting ATPase subunit beta-1-interacting protein 1 isoform 1

    See identical proteins and their annotated locations for NP_080274.2

    Status: VALIDATED

    Source sequence(s)
    FO907130, FQ976844, MH423692
    Consensus CDS
    CCDS57302.1
    UniProtKB/Swiss-Prot
    A6MHP4, Q9D035, Q9D0Q6
    Related
    ENSMUSP00000101614.3, ENSMUST00000105993.4
    Conserved Domains (1) summary
    pfam05640
    Location:10206
    NKAIN; Na,K-Atpase Interacting protein

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000070.7 Reference GRCm39 C57BL/6J

    Range
    130297176..130341115
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_036164361.1XP_036020254.1  sodium/potassium-transporting ATPase subunit beta-1-interacting protein 1 isoform X4

    Conserved Domains (1) summary
    pfam05640
    Location:1110
    NKAIN; Na,K-Atpase Interacting protein
  2. XM_006539117.5XP_006539180.1  sodium/potassium-transporting ATPase subunit beta-1-interacting protein 1 isoform X2

    Conserved Domains (1) summary
    pfam05640
    Location:26210
    NKAIN; Na,K-Atpase Interacting protein
  3. XM_006539116.5XP_006539179.1  sodium/potassium-transporting ATPase subunit beta-1-interacting protein 1 isoform X1

    Conserved Domains (1) summary
    pfam05640
    Location:26213
    NKAIN; Na,K-Atpase Interacting protein
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