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    AGO2 Argonaute family protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 840016, updated on 18-Sep-2024

    Summary

    Official Symbol
    AGO2
    Official Full Name
    Argonaute family protein
    Primary source
    TAIR:AT1G31280
    Locus tag
    AT1G31280
    See related
    Araport:AT1G31280
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    argonaute 2; AtAGO2; T19E23.7; T19E23_7
    Summary
    Encodes Argonaute gene that binds viral siRNAs and is involved in antiviral defense response. Regulates innate immunity.
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    Genomic context

    See AGO2 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    3
    Sequence:
    Chromosome: 1; NC_003070.9 (11181504..11185396)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene miscRNA Neighboring gene ARGONAUTE 3 Neighboring gene TRAM, LAG1 and CLN8 (TLC) lipid-sensing domain containing protein

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Interactions

    General gene information

    NM_102866.3

    Gene Ontology Provided by TAIR

    Component Evidence Code Pubs
    located_in cytoplasm  
    located_in cytosol PubMed 
    located_in nucleus PubMed 
    located_in nucleus PubMed 

    General protein information

    Preferred Names
    Argonaute family protein
    NP_174413.2
    • argonaute 2 (AGO2); FUNCTIONS IN: nucleic acid binding; INVOLVED IN: biological_process unknown; LOCATED IN: cellular_component unknown; EXPRESSED IN: 21 plant structures; EXPRESSED DURING: 12 growth stages; CONTAINS InterPro DOMAIN/s: Domain of unknown function DUF1785 (InterPro:IPR014811), Stem cell self-renewal protein Piwi (InterPro:IPR003165), Argonaute/Dicer protein, PAZ (InterPro:IPR003100), Polynucleotidyl transferase, ribonuclease H fold (InterPro:IPR012337); BEST Arabidopsis thaliana protein match is: ARGONAUTE 3 (TAIR:AT1G31290.1); Has 30240 Blast hits to 14140 proteins in 1171 species: Archae - 11; Bacteria - 7749; Metazoa - 10383; Fungi - 2602; Plants - 5076; Viruses - 357; Other Eukaryotes - 4062 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      11181504..11185396
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_102866.3NP_174413.2  Argonaute family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_174413.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8GX33, Q9SHF3
      UniProtKB/TrEMBL
      A0A178W7B1
      Conserved Domains (5) summary
      PLN03202
      Location:137957
      PLN03202; protein argonaute; Provisional
      cd04657
      Location:528963
      Piwi_ago-like; Piwi_ago-like: PIWI domain, Argonaute-like subfamily. Argonaute is the central component of the RNA-induced silencing complex (RISC) and related complexes. The PIWI domain is the C-terminal portion of Argonaute and consists of two subdomains, one of ...
      pfam02170
      Location:383488
      PAZ; PAZ domain
      pfam08699
      Location:317366
      ArgoL1; Argonaute linker 1 domain
      pfam16486
      Location:164306
      ArgoN; N-terminal domain of argonaute
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