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    SQN peptidyl-prolyl cis-trans isomerase / cyclophilin-40 (CYP40) / rotamase [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 816074, updated on 18-Sep-2024

    Summary

    Official Symbol
    SQN
    Official Full Name
    peptidyl-prolyl cis-trans isomerase / cyclophilin-40 (CYP40) / rotamase
    Primary source
    TAIR:AT2G15790
    Locus tag
    AT2G15790
    See related
    Araport:AT2G15790
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    CYCLOPHILIN 40; CYCLOPHILIN-40; CYP40; F19G14.21; F19G14_21; SQUINT
    Summary
    SQN encodes the Arabidopsis homolog of cyclophilin 40 (CyP40). It is specifically required for the vegetative but not the reproductive maturation of the shoot. Belongs to one of the 36 carboxylate clamp (CC)-tetratricopeptide repeat (TPR) proteins (Prasad 2010, Pubmed ID: 20856808) with potential to interact with Hsp90/Hsp70 as co-chaperones.
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    Genomic context

    See SQN in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    9
    Sequence:
    Chromosome: 2; NC_003071.7 (6877774..6880898, complement)

    Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene Cupredoxin superfamily protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene pseudo Neighboring gene pseudo Neighboring gene pseudo

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Interactions

    General gene information

    NM_127141.3

    Gene Ontology Provided by TAIR

    Component Evidence Code Pubs
    located_in cytoplasm PubMed 
    located_in cytoplasm  

    General protein information

    Preferred Names
    peptidyl-prolyl cis-trans isomerase / cyclophilin-40 (CYP40) / rotamase
    NP_565381.1
    • SQUINT (SQN); CONTAINS InterPro DOMAIN/s: Cyclophilin-like (InterPro:IPR015891), Peptidyl-prolyl cis-trans isomerase, cyclophilin-type (InterPro:IPR002130), Tetratricopeptide-like helical (InterPro:IPR011990), Tetratricopeptide TPR2 (InterPro:IPR013105), Peptidyl-prolyl cis-trans isomerase, cyclophilin-type, conserved site (InterPro:IPR020892), Tetratricopeptide repeat-containing (InterPro:IPR013026), Tetratricopeptide repeat (InterPro:IPR019734); BEST Arabidopsis thaliana protein match is: Cyclophilin-like peptidyl-prolyl cis-trans isomerase family protein (TAIR:AT3G63400.3); Has 20219 Blast hits to 19939 proteins in 2706 species: Archae - 114; Bacteria - 6925; Metazoa - 4764; Fungi - 1760; Plants - 1912; Viruses - 4; Other Eukaryotes - 4740 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003071.7 Reference assembly

      Range
      6877774..6880898 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_127141.3NP_565381.1  peptidyl-prolyl cis-trans isomerase / cyclophilin-40 (CYP40) / rotamase [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_565381.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q08A80, Q9C566, Q9XIL2
      UniProtKB/TrEMBL
      A0A5S9WYM3, A0A654EY88
      Conserved Domains (4) summary
      COG0457
      Location:216345
      TPR; Tetratricopeptide (TPR) repeat [General function prediction only]
      cd01926
      Location:4171
      cyclophilin_ABH_like; Cyclophilin A, B and H-like cyclophilin-type peptidylprolyl cis- trans isomerase (PPIase) domain. This family represents the archetypal cystolic cyclophilin similar to human cyclophilins A, B and H. PPIase is an enzyme which accelerates protein folding ...
      sd00006
      Location:263293
      TPR; TPR repeat [structural motif]
      pfam00515
      Location:298331
      TPR_1; Tetratricopeptide repeat
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