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Camk1g calcium/calmodulin-dependent protein kinase I gamma [ Mus musculus (house mouse) ]

Gene ID: 215303, updated on 9-Dec-2024

Summary

Official Symbol
Camk1gprovided by MGI
Official Full Name
calcium/calmodulin-dependent protein kinase I gammaprovided by MGI
Primary source
MGI:MGI:2388073
See related
Ensembl:ENSMUSG00000016179 AllianceGenome:MGI:2388073
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
CLICK III; CLICK-III; CaMKIgamma
Summary
Enables calcium/calmodulin-dependent protein kinase activity. Predicted to be involved in signal transduction. Located in endomembrane system and plasma membrane. Part of calcium- and calmodulin-dependent protein kinase complex. Is expressed in several structures, including genitourinary system; heart; nervous system; and retina. Orthologous to human CAMK1G (calcium/calmodulin dependent protein kinase IG). [provided by Alliance of Genome Resources, Dec 2024]
Expression
Biased expression in CNS E18 (RPKM 15.3), whole brain E14.5 (RPKM 12.6) and 12 other tissues See more
Orthologs
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Genomic context

See Camk1g in Genome Data Viewer
Location:
1 H6; 1 97.74 cM
Exon count:
15
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 1 NC_000067.7 (193028654..193052636, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 1 NC_000067.6 (193346346..193370355, complement)

Chromosome 1 - NC_000067.7Genomic Context describing neighboring genes Neighboring gene G0/G1 switch gene 2 Neighboring gene laminin, beta 3 Neighboring gene CapStarr-seq enhancer MGSCv37_chr1:195164577-195164848 Neighboring gene predicted gene, 51741 Neighboring gene CapStarr-seq enhancer MGSCv37_chr1:195273620-195273803 Neighboring gene VISTA enhancer mm935 Neighboring gene STARR-seq mESC enhancer starr_03474 Neighboring gene predicted gene, 38022 Neighboring gene predicted gene, 31753

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 
  • Targeted (2)  1 citation

General gene information

Clone Names

  • MGC30513

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables ATP binding  
enables calcium/calmodulin-dependent protein kinase activity  
enables calcium/calmodulin-dependent protein kinase activity PubMed 
enables calcium/calmodulin-dependent protein kinase activity  
enables calmodulin binding  
enables calmodulin binding  
enables protein serine kinase activity  
Process Evidence Code Pubs
involved_in signal transduction  
Component Evidence Code Pubs
located_in Golgi membrane  
part_of calcium- and calmodulin-dependent protein kinase complex PubMed 
is_active_in cytoplasm  
located_in endomembrane system PubMed 
located_in plasma membrane PubMed 

General protein information

Preferred Names
calcium/calmodulin-dependent protein kinase type 1G
Names
caM kinase I gamma
caM kinase IG
caM-KI gamma
caMK-like CREB kinase III
caMKI gamma
caMKIG
NP_001408321.1
NP_001408322.1
NP_659066.1
XP_030108815.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001421392.1NP_001408321.1  calcium/calmodulin-dependent protein kinase type 1G isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC022675
  2. NM_001421393.1NP_001408322.1  calcium/calmodulin-dependent protein kinase type 1G isoform 3

    Status: VALIDATED

    Source sequence(s)
    AC022675
    Related
    ENSMUSP00000128143.2, ENSMUST00000169907.8
  3. NM_144817.3NP_659066.1  calcium/calmodulin-dependent protein kinase type 1G isoform 2

    See identical proteins and their annotated locations for NP_659066.1

    Status: VALIDATED

    Source sequence(s)
    AC022675
    Consensus CDS
    CCDS15638.1
    UniProtKB/Swiss-Prot
    Q91VB2
    Related
    ENSMUSP00000016323.5, ENSMUST00000016323.11
    Conserved Domains (2) summary
    smart00220
    Location:23277
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    cd14166
    Location:19303
    STKc_CaMKI_gamma; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type I gamma

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000067.7 Reference GRCm39 C57BL/6J

    Range
    193028654..193052636 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_030252955.2XP_030108815.1  calcium/calmodulin-dependent protein kinase type 1G isoform X2

    Conserved Domains (1) summary
    cl21453
    Location:1207
    PKc_like; Protein Kinases, catalytic domain
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