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Cdca3 cell division cycle associated 3 [ Rattus norvegicus (Norway rat) ]

Gene ID: 297594, updated on 9-Dec-2024

Summary

Official Symbol
Cdca3provided by RGD
Official Full Name
cell division cycle associated 3provided by RGD
Primary source
RGD:1359093
See related
EnsemblRapid:ENSRNOG00000015529 AllianceGenome:RGD:1359093
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to be involved in cell division and protein ubiquitination. Predicted to be located in adherens junction. Orthologous to human CDCA3 (cell division cycle associated 3). [provided by Alliance of Genome Resources, Dec 2024]
Expression
Biased expression in Testes (RPKM 144.5), Thymus (RPKM 129.1) and 8 other tissues See more
Orthologs
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Genomic context

See Cdca3 in Genome Data Viewer
Location:
4q42
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 4 NC_086022.1 (159321203..159325072)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 4 NC_051339.1 (157634775..157638799)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 4 NC_005103.4 (157347876..157351889)

Chromosome 4 - NC_086022.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC134486638 Neighboring gene leucine rich repeat containing 23 Neighboring gene splA/ryanodine receptor domain and SOCS box containing 2 Neighboring gene triosephosphate isomerase 1 Neighboring gene ubiquitin specific peptidase 5 Neighboring gene G protein subunit beta 3 Neighboring gene prolyl 3-hydroxylase 3 Neighboring gene uncharacterized LOC120102385

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General gene information

Clone Names

  • MGC94266

Gene Ontology Provided by RGD

Process Evidence Code Pubs
involved_in cell division  
involved_in protein ubiquitination  
Component Evidence Code Pubs
located_in adherens junction  
located_in cytosol  

General protein information

Preferred Names
cell division cycle-associated protein 3
Names
TOME-1
trigger of mitotic entry protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001007648.1NP_001007649.1  cell division cycle-associated protein 3

    See identical proteins and their annotated locations for NP_001007649.1

    Status: PROVISIONAL

    Source sequence(s)
    BC079204
    UniProtKB/Swiss-Prot
    Q68FW2
    UniProtKB/TrEMBL
    A0A8I6AGY5, A6ILL8
    Conserved Domains (1) summary
    PHA03301
    Location:476
    PHA03301; envelope glycoprotein L; Provisional

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086022.1 Reference GRCr8

    Range
    159321203..159325072
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006237342.5XP_006237404.1  cell division cycle-associated protein 3 isoform X2

    See identical proteins and their annotated locations for XP_006237404.1

    UniProtKB/TrEMBL
    A0A8I6AGY5
    Related
    ENSRNOP00000020803.5, ENSRNOT00000020803.6
  2. XM_006237341.4XP_006237403.1  cell division cycle-associated protein 3 isoform X1

    See identical proteins and their annotated locations for XP_006237403.1

    UniProtKB/Swiss-Prot
    Q68FW2
    UniProtKB/TrEMBL
    A0A8I6AGY5, A6ILL8
    Related
    ENSRNOP00000091987.2, ENSRNOT00000102564.2
    Conserved Domains (1) summary
    PHA03301
    Location:476
    PHA03301; envelope glycoprotein L; Provisional
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