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    hmgb2b high mobility group box 2b [ Danio rerio (zebrafish) ]

    Gene ID: 447936, updated on 9-Dec-2024

    Summary

    Official Symbol
    hmgb2bprovided by ZNC
    Official Full Name
    high mobility group box 2bprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040912-122
    See related
    Ensembl:ENSDARG00000053990 AllianceGenome:ZFIN:ZDB-GENE-040912-122
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    hmgb2; hmgb2l; im:6909096; wu:fa20b02; zgc:101854
    Summary
    Predicted to enable DNA binding activity, bending. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Is expressed in axis; gut; nervous system; ovary; and pectoral fin bud. Orthologous to human HMGB2 (high mobility group box 2). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See hmgb2b in Genome Data Viewer
    Location:
    chromosome: 23
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 23 NC_007134.7 (45025911..45029560)
    105 previous assembly GRCz10 (GCF_000002035.5) 23 NC_007134.6 (45264004..45267653, complement)

    Chromosome 23 - NC_007134.7Genomic Context describing neighboring genes Neighboring gene transferrin receptor 2 Neighboring gene CTS telomere maintenance complex component 1 Neighboring gene SH3 domain containing GRB2 like 2b, endophilin A1 Neighboring gene si:ch73-168d20.1

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables DNA binding  
    enables DNA binding, bending  
    Component Evidence Code Pubs
    located_in nucleus  

    General protein information

    Preferred Names
    high mobility group protein B2b
    Names
    high-mobility group box 2, like

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001004674.1NP_001004674.1  high mobility group protein B2b

      See identical proteins and their annotated locations for NP_001004674.1

      Status: PROVISIONAL

      Source sequence(s)
      BC081415
      UniProtKB/TrEMBL
      B2GRJ5, Q66IB6
      Related
      ENSDARP00000153222.1, ENSDART00000188105.1
      Conserved Domains (2) summary
      pfam00505
      Location:97164
      HMG_box; HMG (high mobility group) box
      pfam09011
      Location:778
      HMG_box_2; HMG-box domain

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007134.7 Reference GRCz11 Primary Assembly

      Range
      45025911..45029560
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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