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lrrc59 leucine rich repeat containing 59 [ Danio rerio (zebrafish) ]

Gene ID: 405868, updated on 9-Dec-2024

Summary

Official Symbol
lrrc59provided by ZNC
Official Full Name
leucine rich repeat containing 59provided by ZNC
Primary source
ZFIN:ZDB-GENE-040426-2547
See related
Ensembl:ENSDARG00000071426 AllianceGenome:ZFIN:ZDB-GENE-040426-2547
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
zgc:85752
Summary
Predicted to enable protein serine/threonine phosphatase activity. Predicted to be involved in intracellular signal transduction. Predicted to be located in endoplasmic reticulum membrane and nuclear envelope. Predicted to be active in cytoplasm. Is expressed in several structures, including axis; hatching gland; notochord; otic vesicle; and polster. Orthologous to human LRRC59 (leucine rich repeat containing 59). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
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Genomic context

See lrrc59 in Genome Data Viewer
Location:
chromosome: 12
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 12 NC_007123.7 (31783145..31787861)
105 previous assembly GRCz10 (GCF_000002035.5) 12 NC_007123.6 (31668243..31672959)

Chromosome 12 - NC_007123.7Genomic Context describing neighboring genes Neighboring gene 5-hydroxytryptamine receptor 3A-like Neighboring gene uncharacterized LOC137490452 Neighboring gene N-acetyltransferase 9 Neighboring gene glutamate receptor, ionotropic, N-methyl D-aspartate 2Cb Neighboring gene microRNA mir-2196

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Interactions

General gene information

Clone Names

  • MGC85752

Gene Ontology Provided by ZFIN

Component Evidence Code Pubs
is_active_in cytoplasm  
located_in endoplasmic reticulum  
located_in endoplasmic reticulum membrane  
located_in intracellular membrane-bounded organelle  
located_in membrane  
located_in nuclear envelope  
located_in nucleus  

General protein information

Preferred Names
leucine-rich repeat-containing protein 59

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_212932.1NP_998097.1  leucine-rich repeat-containing protein 59

    See identical proteins and their annotated locations for NP_998097.1

    Status: PROVISIONAL

    Source sequence(s)
    BC067603
    UniProtKB/Swiss-Prot
    Q6NWG1
    Related
    ENSDARP00000096361.3, ENSDART00000105584.4
    Conserved Domains (3) summary
    sd00031
    Location:1738
    LRR_1; leucine-rich repeat [structural motif]
    pfam12799
    Location:84120
    LRR_4; Leucine Rich repeats (2 copies)
    pfam13855
    Location:60118
    LRR_8; Leucine rich repeat

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007123.7 Reference GRCz11 Primary Assembly

    Range
    31783145..31787861
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCz11 ALT_DRER_TU_1

Genomic

  1. NW_018394853.1 Reference GRCz11 ALT_DRER_TU_1

    Range
    48667..53383
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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