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F27D9.7 Peptidase M12B domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 185019, updated on 9-Dec-2024

Summary

Official Symbol
F27D9.7
Official Full Name
Peptidase M12B domain-containing protein
Primary source
WormBase:WBGene00017865
Locus tag
CELE_F27D9.7
See related
AllianceGenome:WB:WBGene00017865
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable metalloendopeptidase activity. Predicted to be involved in membrane protein ectodomain proteolysis. Predicted to be located in membrane. Orthologous to human ADAMDEC1 (ADAM like decysin 1). [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

See F27D9.7 in Genome Data Viewer
Location:
chromosome: X
Exon count:
8
Sequence:
Chromosome: X; NC_003284.9 (7667333..7670755, complement)

Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene NADP-retinol dehydrogenase Neighboring gene ncRNA Neighboring gene VWFA domain-containing protein Neighboring gene Major facilitator superfamily (MFS) profile domain-containing protein Neighboring gene PDZ domain-containing protein

General gene information

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables metal ion binding  
enables metalloendopeptidase activity  
enables metalloendopeptidase activity  
enables metallopeptidase activity  
Process Evidence Code Pubs
involved_in membrane protein ectodomain proteolysis  
involved_in proteolysis  
Component Evidence Code Pubs
located_in membrane  

General protein information

Preferred Names
Peptidase M12B domain-containing protein
NP_509295.3
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003284.9 Reference assembly

    Range
    7667333..7670755 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_076894.6NP_509295.3  Peptidase M12B domain-containing protein [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q19844
    Conserved Domains (2) summary
    pfam01421
    Location:56218
    Reprolysin; Reprolysin (M12B) family zinc metalloprotease
    cl10507
    Location:246272
    Disintegrin
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