U.S. flag

An official website of the United States government

CG5608 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 41543, updated on 9-Dec-2024

Summary

Official Symbol
CG5608provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0038058
Locus tag
Dmel_CG5608
See related
AllianceGenome:FB:FBgn0038058
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Dmel\CG5608; Vac14
Summary
Predicted to be involved in phosphatidylinositol biosynthetic process. Predicted to be part of PAS complex. Predicted to be active in endosome membrane. Is expressed in adult head. Human ortholog(s) of this gene implicated in striatonigral degeneration. Orthologous to human VAC14 (VAC14 component of PIKFYVE complex). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See CG5608 in Genome Data Viewer
Location:
87B11-87B12; 3-52 cM
Exon count:
9
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (12462562..12465298, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (8288284..8291020, complement)

Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene toys are us Neighboring gene uncharacterized protein Neighboring gene RNA polymerase III subunit C Neighboring gene Heat shock protein 70 Ba Neighboring gene alphagamma-element:CR32865

Genomic regions, transcripts, and products

Interactions

General gene information

Gene Ontology Provided by FlyBase

Component Evidence Code Pubs
part_of PAS complex  
part_of PAS complex  
is_active_in endosome membrane  

General protein information

Preferred Names
uncharacterized protein
Names
CG5608-PA

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033777.3 Reference assembly

    Range
    12462562..12465298 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_141951.1NP_650208.1  uncharacterized protein Dmel_CG5608 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_650208.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8T989, Q9VG59
    Related
    FBpp0082148, FBtr0082680
    Conserved Domains (3) summary
    pfam11916
    Location:452629
    Vac14_Fig4_bd; Vacuolar protein 14 C-terminal Fig4p binding
    pfam12755
    Location:65161
    Vac14_Fab1_bd; Vacuolar 14 Fab1-binding region
    sd00044
    Location:4579
    HEAT; HEAT repeat [structural motif]
External link. Please review our privacy policy.