Replication interactions
Interaction |
Pubs |
Knockdown of DnaJ (Hsp40) homolog, subfamily A, member 1 (DNAJA1) by siRNA inhibits HIV-1 replication in CD4+/CCR5+/CXCR4+ TZM-bl HeLa cells |
PubMed
|
Protein interactions
Protein |
Gene |
Interaction |
Pubs |
Rev
|
rev
|
The expression of HSP40A1 (DNAJA1) inhibits HIV-1 Rev expression at the posttranscriptional levels, leading to the reduction of HIV-1 RNA accumulation |
PubMed
|
Vif
|
vif
|
HIV-1 Vif interacts with DNAJA1; interaction predicted to be relevant in protein folding and/or macromolecular structure assembly |
PubMed
|
capsid
|
gag
|
HSP40A1 (DNAJA1) inhibits HIV-1 production as measured by the level of viral p24 capsid in the culture supernatant. The HSP40A1 (1-83) mutant lacking most of the C-terminal portion is more potent in inhibiting HIV-1 production than its wild-type |
PubMed
|
Go to the HIV-1, Human Interaction Database