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WRR4 Disease resistance protein (TIR-NBS-LRR class) [ Arabidopsis thaliana (thale cress) ]

Gene ID: 842104, updated on 18-Sep-2024

Summary

Official Symbol
WRR4
Official Full Name
Disease resistance protein (TIR-NBS-LRR class)
Primary source
TAIR:AT1G56510
Locus tag
AT1G56510
See related
Araport:AT1G56510
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
ACTIVATED DISEASE RESISTANCE 2; ADR2; F13N6.5; F13N6_5; WHITE RUST RESISTANCE 4
Summary
TIR-NB-LRR protein that confers resistance to four races of Albugo candida.
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Genomic context

See WRR4 in Genome Data Viewer
Location:
chromosome: 1
Exon count:
5
Sequence:
Chromosome: 1; NC_003070.9 (21167565..21173632)

Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene miscRNA Neighboring gene haloacid dehalogenase-like hydrolase family protein Neighboring gene Disease resistance protein (TIR-NBS-LRR class) family Neighboring gene hydroxyproline-rich glycoprotein family protein

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

General gene information

NM_104527.4

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables ADP binding  
enables NAD+ nucleotidase, cyclic ADP-ribose generating  
Component Evidence Code Pubs
located_in chloroplast  
located_in cytoplasm PubMed 

General protein information

Preferred Names
Disease resistance protein (TIR-NBS-LRR class)
NP_176043.1
  • WHITE RUST RESISTANCE 4 (WRR4); FUNCTIONS IN: transmembrane receptor activity, nucleoside-triphosphatase activity, nucleotide binding, ATP binding; INVOLVED IN: defense response to fungus, incompatible interaction, defense response; LOCATED IN: intrinsic to membrane; EXPRESSED IN: 17 plant structures; EXPRESSED DURING: 10 growth stages; CONTAINS InterPro DOMAIN/s: ATPase, AAA+ type, core (InterPro:IPR003593), NB-ARC (InterPro:IPR002182), Toll-Interleukin receptor (InterPro:IPR000157), Disease resistance protein (InterPro:IPR000767); BEST Arabidopsis thaliana protein match is: Disease resistance protein (TIR-NBS-LRR class) family (TAIR:AT1G56540.1); Has 19205 Blast hits to 15135 proteins in 571 species: Archae - 14; Bacteria - 975; Metazoa - 1259; Fungi - 71; Plants - 16420; Viruses - 8; Other Eukaryotes - 458 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003070.9 Reference assembly

    Range
    21167565..21173632
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_104527.4NP_176043.1  Disease resistance protein (TIR-NBS-LRR class) [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_176043.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9C7X0
    UniProtKB/TrEMBL
    A0A5S9WQ84, A0A654EP54
    Conserved Domains (6) summary
    PLN03210
    Location:1997
    PLN03210; Resistant to P. syringae 6; Provisional
    sd00033
    Location:603621
    LRR_RI; leucine-rich repeat [structural motif]
    sd00034
    Location:626648
    LRR_AMN1; leucine-rich repeat [structural motif]
    pfam01582
    Location:13176
    TIR; TIR domain
    pfam07725
    Location:602621
    LRR_3; Leucine Rich Repeat
    pfam13191
    Location:187310
    AAA_16; AAA ATPase domain
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