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Gpx8 glutathione peroxidase 8 (putative) [ Mus musculus (house mouse) ]

Gene ID: 69590, updated on 9-Dec-2024

Summary

Official Symbol
Gpx8provided by MGI
Official Full Name
glutathione peroxidase 8 (putative)provided by MGI
Primary source
MGI:MGI:1916840
See related
Ensembl:ENSMUSG00000021760 AllianceGenome:MGI:1916840
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
GPx-8; GSHPx-8; 2310016C16Rik
Summary
Predicted to enable peroxidase activity. Predicted to be involved in cellular oxidant detoxification and response to oxidative stress. Predicted to be located in membrane. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; respiratory system; and sensory organ. Orthologous to human GPX8 (glutathione peroxidase 8 (putative)). [provided by Alliance of Genome Resources, Dec 2024]
Expression
Broad expression in bladder adult (RPKM 34.1), limb E14.5 (RPKM 30.3) and 16 other tissues See more
Orthologs
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Genomic context

See Gpx8 in Genome Data Viewer
Location:
13 D2.2; 13 63.93 cM
Exon count:
3
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 13 NC_000079.7 (113179287..113182944, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 13 NC_000079.6 (113042757..113046430, complement)

Chromosome 13 - NC_000079.7Genomic Context describing neighboring genes Neighboring gene cell division cycle 20B Neighboring gene microRNA 449b Neighboring gene microRNA 449a Neighboring gene granzyme A Neighboring gene RIKEN cDNA 1700084D21 gene

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (2) 
  • Targeted (1)  1 citation

Pathways from PubChem

Interactions

General gene information

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables glutathione peroxidase activity  
enables peroxidase activity  
enables peroxidase activity  
Component Evidence Code Pubs
is_active_in cellular_component  
located_in membrane  

General protein information

Preferred Names
probable glutathione peroxidase 8
NP_001405547.1
NP_081403.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001418618.1NP_001405547.1  probable glutathione peroxidase 8 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC159207, AC165265
    UniProtKB/TrEMBL
    A0A338P7G6
    Related
    ENSMUSP00000156385.2, ENSMUST00000231962.2
  2. NM_027127.3NP_081403.1  probable glutathione peroxidase 8 isoform 1

    See identical proteins and their annotated locations for NP_081403.1

    Status: VALIDATED

    Source sequence(s)
    AC159207, AC165265
    Consensus CDS
    CCDS26781.1
    UniProtKB/Swiss-Prot
    Q8VE68, Q9D7B7
    Related
    ENSMUSP00000022282.4, ENSMUST00000022282.6
    Conserved Domains (1) summary
    TIGR02540
    Location:46198
    gpx7; putative glutathione peroxidase Gpx7

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000079.7 Reference GRCm39 C57BL/6J

    Range
    113179287..113182944 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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