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    Btrc beta-transducin repeat containing protein [ Mus musculus (house mouse) ]

    Gene ID: 12234, updated on 9-Dec-2024

    Summary

    Official Symbol
    Btrcprovided by MGI
    Official Full Name
    beta-transducin repeat containing proteinprovided by MGI
    Primary source
    MGI:MGI:1338871
    See related
    Ensembl:ENSMUSG00000025217 AllianceGenome:MGI:1338871
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    HOS; FWD1; Fbw1a; Slimb; b-TrCP; beta-TrCP; Beta-Trcp1; SCF b-TRCP; E3RSIkappaB; E3RS-IkappaB
    Summary
    Enables beta-catenin binding activity; protein phosphorylated amino acid binding activity; and ubiquitin protein ligase activity. Involved in several processes, including SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; protein dephosphorylation; and regulation of canonical Wnt signaling pathway. Acts upstream of or within several processes, including mammary gland epithelium development; protein K48-linked ubiquitination; and regulation of canonical NF-kappaB signal transduction. Located in cytoplasm and nucleus. Is expressed in several structures, including central nervous system; genitourinary system; gut; peripheral nervous system; and respiratory system. Orthologous to human BTRC (beta-transducin repeat containing E3 ubiquitin protein ligase). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Ubiquitous expression in frontal lobe adult (RPKM 10.9), CNS E18 (RPKM 10.0) and 28 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Btrc in Genome Data Viewer
    Location:
    19 C3; 19 38.75 cM
    Exon count:
    21
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 19 NC_000085.7 (45352119..45521782)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 19 NC_000085.6 (45363688..45533343)

    Chromosome 19 - NC_000085.7Genomic Context describing neighboring genes Neighboring gene predicted gene 28578 Neighboring gene STARR-seq mESC enhancer starr_46273 Neighboring gene predicted gene 29593 Neighboring gene STARR-positive B cell enhancer mm9_chr19:45437848-45438148 Neighboring gene ribosomal protein S2 pseudogene Neighboring gene ribosomal protein L6 pseudogene Neighboring gene CapStarr-seq enhancer MGSCv37_chr19:45602595-45602796 Neighboring gene predicted gene, 41856 Neighboring gene CapStarr-seq enhancer MGSCv37_chr19:45634643-45634844 Neighboring gene STARR-positive B cell enhancer ABC_E9999 Neighboring gene predicted gene, 19639 Neighboring gene polymerase (DNA directed), lambda Neighboring gene deleted in primary ciliary dyskinesia

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (3) 
    • Targeted (5)  1 citation

    Pathways from PubChem

    Interactions

    General gene information

    Clone Names

    • KIAA4123, mKIAA4123

    Gene Ontology Provided by MGI

    Items 1 - 25 of 43
    Process Evidence Code Pubs
    acts_upstream_of_or_within SCF-dependent proteasomal ubiquitin-dependent protein catabolic process PubMed 
    involved_in SCF-dependent proteasomal ubiquitin-dependent protein catabolic process PubMed 
    involved_in SCF-dependent proteasomal ubiquitin-dependent protein catabolic process  
    involved_in Wnt signaling pathway  
    acts_upstream_of_or_within branching involved in mammary gland duct morphogenesis PubMed 
    acts_upstream_of_or_within cellular response to organic cyclic compound PubMed 
    acts_upstream_of_or_within mammary gland epithelial cell proliferation PubMed 
    involved_in negative regulation of DNA-templated transcription  
    involved_in negative regulation of DNA-templated transcription  
    involved_in negative regulation of T cell receptor signaling pathway  
    involved_in negative regulation of T cell receptor signaling pathway  
    involved_in non-canonical NF-kappaB signal transduction  
    involved_in non-canonical NF-kappaB signal transduction  
    involved_in positive regulation of DNA-templated transcription PubMed 
    involved_in positive regulation of circadian rhythm PubMed 
    involved_in positive regulation of proteolysis  
    involved_in positive regulation of proteolysis  
    involved_in positive regulation of ubiquitin protein ligase activity  
    involved_in proteasome-mediated ubiquitin-dependent protein catabolic process  
    involved_in proteasome-mediated ubiquitin-dependent protein catabolic process  
    acts_upstream_of_or_within protein K48-linked ubiquitination PubMed 
    involved_in protein K48-linked ubiquitination  
    acts_upstream_of_or_within protein catabolic process PubMed 
    involved_in protein dephosphorylation PubMed 
    involved_in protein destabilization  
    involved_in protein destabilization  
    involved_in protein polyubiquitination  
    involved_in protein polyubiquitination PubMed 
    involved_in protein polyubiquitination  
    acts_upstream_of_or_within protein ubiquitination PubMed 
    involved_in protein ubiquitination  
    involved_in proteolysis  
    acts_upstream_of_or_within regulation of canonical NF-kappaB signal transduction PubMed 
    involved_in regulation of canonical Wnt signaling pathway PubMed 
    involved_in regulation of cell cycle  
    acts_upstream_of_or_within regulation of cell cycle PubMed 
    involved_in regulation of circadian rhythm  
    involved_in regulation of circadian rhythm  
    involved_in regulation of proteasomal protein catabolic process  
    acts_upstream_of_or_within regulation of proteasomal protein catabolic process PubMed 
    involved_in rhythmic process  
    involved_in ubiquitin-dependent protein catabolic process  
    involved_in ubiquitin-dependent protein catabolic process  
    Items 1 - 25 of 43
    Component Evidence Code Pubs
    part_of SCF ubiquitin ligase complex  
    part_of SCF ubiquitin ligase complex  
    part_of SCF ubiquitin ligase complex  
    is_active_in cytoplasm  
    located_in cytoplasm PubMed 
    located_in cytosol  
    is_active_in nucleus  
    located_in nucleus PubMed 

    General protein information

    Preferred Names
    F-box/WD repeat-containing protein 1A

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001037758.2NP_001032847.2  F-box/WD repeat-containing protein 1A isoform a

      See identical proteins and their annotated locations for NP_001032847.2

      Status: VALIDATED

      Source sequence(s)
      AC126454, AK052317, AK145624, BP768842, BY070850, BY290279
      Consensus CDS
      CCDS29860.1
      UniProtKB/Swiss-Prot
      Q3U0Q4, Q3ULA2, Q571K6, Q9QUI5, Q9R1G7, Q9Z159
      Related
      ENSMUSP00000070728.6, ENSMUST00000065601.13
      Conserved Domains (5) summary
      COG2319
      Location:290586
      WD40; WD40 repeat [General function prediction only]
      cd00200
      Location:303581
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      pfam12125
      Location:139177
      Beta-TrCP_D; D domain of beta-TrCP
      pfam12937
      Location:181228
      F-box-like; F-box-like
      sd00039
      Location:306341
      7WD40; WD40 repeat [structural motif]
    2. NM_001286465.1NP_001273394.1  F-box/WD repeat-containing protein 1A isoform a

      See identical proteins and their annotated locations for NP_001273394.1

      Status: VALIDATED

      Source sequence(s)
      AC126454, AK052317, AK145624, BP768842, BY070850, BY290279
      Consensus CDS
      CCDS29860.1
      UniProtKB/Swiss-Prot
      Q3U0Q4, Q3ULA2, Q571K6, Q9QUI5, Q9R1G7, Q9Z159
      Conserved Domains (5) summary
      COG2319
      Location:290586
      WD40; WD40 repeat [General function prediction only]
      cd00200
      Location:303581
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      pfam12125
      Location:139177
      Beta-TrCP_D; D domain of beta-TrCP
      pfam12937
      Location:181228
      F-box-like; F-box-like
      sd00039
      Location:306341
      7WD40; WD40 repeat [structural motif]
    3. NM_001286466.1NP_001273395.1  F-box/WD repeat-containing protein 1A isoform c

      Status: VALIDATED

      Source sequence(s)
      AC126454, AK052317, AK145624, BP768842, BY070850, BY290279
      UniProtKB/Swiss-Prot
      Q3ULA2
      Conserved Domains (3) summary
      COG2319
      Location:68364
      WD40; WD40 repeat [General function prediction only]
      cd00200
      Location:81359
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:84119
      7WD40; WD40 repeat [structural motif]
    4. NM_001360120.1NP_001347049.1  F-box/WD repeat-containing protein 1A isoform d

      Status: VALIDATED

      Source sequence(s)
      AC123058, AC126454, BP768842
      Conserved Domains (4) summary
      cd00200
      Location:317595
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:320355
      7WD40; WD40 repeat [structural motif]
      pfam12125
      Location:153191
      Beta-TrCP_D; D domain of beta-TrCP
      pfam12937
      Location:195242
      F-box-like
    5. NM_001360122.1NP_001347051.1  F-box/WD repeat-containing protein 1A isoform e

      Status: VALIDATED

      Source sequence(s)
      AC123058, AC126454, BP768842
      Conserved Domains (4) summary
      cd00200
      Location:291569
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:294329
      7WD40; WD40 repeat [structural motif]
      pfam12125
      Location:127165
      Beta-TrCP_D; D domain of beta-TrCP
      pfam12937
      Location:169216
      F-box-like
    6. NM_001360124.1NP_001347053.1  F-box/WD repeat-containing protein 1A isoform f

      Status: VALIDATED

      Source sequence(s)
      AC123058, AC126454, BP768842
      Conserved Domains (4) summary
      cd00200
      Location:285563
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:288323
      7WD40; WD40 repeat [structural motif]
      pfam12125
      Location:121159
      Beta-TrCP_D; D domain of beta-TrCP
      pfam12937
      Location:163210
      F-box-like
    7. NM_001360126.1NP_001347055.1  F-box/WD repeat-containing protein 1A isoform g

      Status: VALIDATED

      Source sequence(s)
      AC123058, AC126454, BP768842
      Conserved Domains (4) summary
      cd00200
      Location:281559
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:284319
      7WD40; WD40 repeat [structural motif]
      pfam12125
      Location:117155
      Beta-TrCP_D; D domain of beta-TrCP
      pfam12937
      Location:159206
      F-box-like; F-box-like
    8. NM_001360127.1NP_001347056.1  F-box/WD repeat-containing protein 1A isoform h

      Status: VALIDATED

      Source sequence(s)
      AC123058, AC126454, BP768842
      Conserved Domains (4) summary
      cd00200
      Location:277555
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:280315
      7WD40; WD40 repeat [structural motif]
      pfam12125
      Location:113151
      Beta-TrCP_D; D domain of beta-TrCP
      pfam12937
      Location:155202
      F-box-like; F-box-like
    9. NM_001409992.1NP_001396921.1  F-box/WD repeat-containing protein 1A isoform f

      Status: VALIDATED

      Source sequence(s)
      AC123058, AC126454
    10. NM_009771.3NP_033901.1  F-box/WD repeat-containing protein 1A isoform b

      See identical proteins and their annotated locations for NP_033901.1

      Status: VALIDATED

      Source sequence(s)
      AC126454, AK052317, AK145624, BP768842, BY070850, BY290279
      Consensus CDS
      CCDS38002.1
      UniProtKB/Swiss-Prot
      Q3ULA2
      Related
      ENSMUSP00000107567.3, ENSMUST00000111936.4
      Conserved Domains (5) summary
      COG2319
      Location:254550
      WD40; WD40 repeat [General function prediction only]
      cd00200
      Location:267545
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      pfam12125
      Location:103141
      Beta-TrCP_D; D domain of beta-TrCP
      pfam12937
      Location:145192
      F-box-like; F-box-like
      sd00039
      Location:270305
      7WD40; WD40 repeat [structural motif]

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000085.7 Reference GRCm39 C57BL/6J

      Range
      45352119..45521782
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011247119.4XP_011245421.1  F-box/WD repeat-containing protein 1A isoform X3

      Conserved Domains (4) summary
      cd00200
      Location:287565
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:290325
      7WD40; WD40 repeat [structural motif]
      pfam12125
      Location:123161
      Beta-TrCP_D; D domain of beta-TrCP
      pfam12937
      Location:165212
      F-box-like
    2. XM_036161407.1XP_036017300.1  F-box/WD repeat-containing protein 1A isoform X3

      Conserved Domains (4) summary
      cd00200
      Location:287565
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:290325
      7WD40; WD40 repeat [structural motif]
      pfam12125
      Location:123161
      Beta-TrCP_D; D domain of beta-TrCP
      pfam12937
      Location:165212
      F-box-like
    3. XM_006526614.5XP_006526677.2  F-box/WD repeat-containing protein 1A isoform X7

      Conserved Domains (4) summary
      cd00200
      Location:261539
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:264299
      7WD40; WD40 repeat [structural motif]
      pfam12125
      Location:97135
      Beta-TrCP_D; D domain of beta-TrCP
      pfam12937
      Location:139186
      F-box-like
    4. XM_030250718.2XP_030106578.1  F-box/WD repeat-containing protein 1A isoform X11

      Conserved Domains (4) summary
      cd00200
      Location:251529
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:254289
      7WD40; WD40 repeat [structural motif]
      pfam12125
      Location:87125
      Beta-TrCP_D; D domain of beta-TrCP
      pfam12937
      Location:129176
      F-box-like
    5. XM_011247123.4XP_011245425.1  F-box/WD repeat-containing protein 1A isoform X9

      Conserved Domains (4) summary
      cd00200
      Location:255533
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:258293
      7WD40; WD40 repeat [structural motif]
      pfam12125
      Location:91129
      Beta-TrCP_D; D domain of beta-TrCP
      pfam12937
      Location:133180
      F-box-like
    6. XM_036161413.1XP_036017306.1  F-box/WD repeat-containing protein 1A isoform X9

      Conserved Domains (4) summary
      cd00200
      Location:255533
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:258293
      7WD40; WD40 repeat [structural motif]
      pfam12125
      Location:91129
      Beta-TrCP_D; D domain of beta-TrCP
      pfam12937
      Location:133180
      F-box-like
    7. XM_030250714.2XP_030106574.1  F-box/WD repeat-containing protein 1A isoform X6

      Conserved Domains (4) summary
      cd00200
      Location:273551
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:276311
      7WD40; WD40 repeat [structural motif]
      pfam12125
      Location:109147
      Beta-TrCP_D; D domain of beta-TrCP
      pfam12937
      Location:151198
      F-box-like
    8. XM_030250719.2XP_030106579.1  F-box/WD repeat-containing protein 1A isoform X12

      Conserved Domains (4) summary
      cd00200
      Location:247525
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:250285
      7WD40; WD40 repeat [structural motif]
      pfam12125
      Location:83121
      Beta-TrCP_D; D domain of beta-TrCP
      pfam12937
      Location:125172
      F-box-like
    9. XM_006526613.4XP_006526676.1  F-box/WD repeat-containing protein 1A isoform X14

      Conserved Domains (4) summary
      cd00200
      Location:237515
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:240275
      7WD40; WD40 repeat [structural motif]
      pfam12125
      Location:73111
      Beta-TrCP_D; D domain of beta-TrCP
      pfam12937
      Location:115162
      F-box-like
    10. XM_006526612.4XP_006526675.1  F-box/WD repeat-containing protein 1A isoform X13

      Conserved Domains (4) summary
      cd00200
      Location:241519
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:244279
      7WD40; WD40 repeat [structural motif]
      pfam12125
      Location:77115
      Beta-TrCP_D; D domain of beta-TrCP
      pfam12937
      Location:119166
      F-box-like
    11. XM_036161405.1XP_036017298.1  F-box/WD repeat-containing protein 1A isoform X1

      Conserved Domains (4) summary
      cd00200
      Location:317595
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:320355
      7WD40; WD40 repeat [structural motif]
      pfam12125
      Location:153191
      Beta-TrCP_D; D domain of beta-TrCP
      pfam12937
      Location:195242
      F-box-like
    12. XM_036161406.1XP_036017299.1  F-box/WD repeat-containing protein 1A isoform X2

      Conserved Domains (4) summary
      cd00200
      Location:291569
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:294329
      7WD40; WD40 repeat [structural motif]
      pfam12125
      Location:127165
      Beta-TrCP_D; D domain of beta-TrCP
      pfam12937
      Location:169216
      F-box-like
    13. XM_030250713.2XP_030106573.1  F-box/WD repeat-containing protein 1A isoform X4

      Conserved Domains (4) summary
      cd00200
      Location:285563
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:288323
      7WD40; WD40 repeat [structural motif]
      pfam12125
      Location:121159
      Beta-TrCP_D; D domain of beta-TrCP
      pfam12937
      Location:163210
      F-box-like
    14. XM_030250721.2XP_030106581.1  F-box/WD repeat-containing protein 1A isoform X15

      UniProtKB/TrEMBL
      A0A286YDT6
      Conserved Domains (4) summary
      cd00200
      Location:204482
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:207242
      7WD40; WD40 repeat [structural motif]
      pfam12125
      Location:4078
      Beta-TrCP_D; D domain of beta-TrCP
      pfam12937
      Location:82129
      F-box-like
    15. XM_036161408.1XP_036017301.1  F-box/WD repeat-containing protein 1A isoform X4

      Conserved Domains (4) summary
      cd00200
      Location:285563
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:288323
      7WD40; WD40 repeat [structural motif]
      pfam12125
      Location:121159
      Beta-TrCP_D; D domain of beta-TrCP
      pfam12937
      Location:163210
      F-box-like
    16. XM_030250711.1XP_030106571.1  F-box/WD repeat-containing protein 1A isoform X4

      Conserved Domains (4) summary
      cd00200
      Location:285563
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:288323
      7WD40; WD40 repeat [structural motif]
      pfam12125
      Location:121159
      Beta-TrCP_D; D domain of beta-TrCP
      pfam12937
      Location:163210
      F-box-like
    17. XM_030250715.1XP_030106575.1  F-box/WD repeat-containing protein 1A isoform X8

      Conserved Domains (4) summary
      cd00200
      Location:259537
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:262297
      7WD40; WD40 repeat [structural motif]
      pfam12125
      Location:95133
      Beta-TrCP_D; D domain of beta-TrCP
      pfam12937
      Location:137184
      F-box-like
    18. XM_030250720.1XP_030106580.1  F-box/WD repeat-containing protein 1A isoform X15

      UniProtKB/TrEMBL
      A0A286YDT6
      Conserved Domains (4) summary
      cd00200
      Location:204482
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:207242
      7WD40; WD40 repeat [structural motif]
      pfam12125
      Location:4078
      Beta-TrCP_D; D domain of beta-TrCP
      pfam12937
      Location:82129
      F-box-like
    19. XM_036161409.1XP_036017302.1  F-box/WD repeat-containing protein 1A isoform X4

      Conserved Domains (4) summary
      cd00200
      Location:285563
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:288323
      7WD40; WD40 repeat [structural motif]
      pfam12125
      Location:121159
      Beta-TrCP_D; D domain of beta-TrCP
      pfam12937
      Location:163210
      F-box-like
    20. XM_036161412.1XP_036017305.1  F-box/WD repeat-containing protein 1A isoform X10

      Conserved Domains (4) summary
      cd00200
      Location:255533
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:258293
      7WD40; WD40 repeat [structural motif]
      pfam12125
      Location:91129
      Beta-TrCP_D; D domain of beta-TrCP
      pfam12937
      Location:133180
      F-box-like
    21. XM_030250716.1XP_030106576.1  F-box/WD repeat-containing protein 1A isoform X10

      Conserved Domains (4) summary
      cd00200
      Location:255533
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:258293
      7WD40; WD40 repeat [structural motif]
      pfam12125
      Location:91129
      Beta-TrCP_D; D domain of beta-TrCP
      pfam12937
      Location:133180
      F-box-like
    22. XM_030250712.1XP_030106572.1  F-box/WD repeat-containing protein 1A isoform X4

      Conserved Domains (4) summary
      cd00200
      Location:285563
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:288323
      7WD40; WD40 repeat [structural motif]
      pfam12125
      Location:121159
      Beta-TrCP_D; D domain of beta-TrCP
      pfam12937
      Location:163210
      F-box-like
    23. XM_036161410.1XP_036017303.1  F-box/WD repeat-containing protein 1A isoform X8

      Conserved Domains (4) summary
      cd00200
      Location:259537
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:262297
      7WD40; WD40 repeat [structural motif]
      pfam12125
      Location:95133
      Beta-TrCP_D; D domain of beta-TrCP
      pfam12937
      Location:137184
      F-box-like
    24. XM_036161411.1XP_036017304.1  F-box/WD repeat-containing protein 1A isoform X8

      Conserved Domains (4) summary
      cd00200
      Location:259537
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:262297
      7WD40; WD40 repeat [structural motif]
      pfam12125
      Location:95133
      Beta-TrCP_D; D domain of beta-TrCP
      pfam12937
      Location:137184
      F-box-like
    25. XM_011247127.3XP_011245429.1  F-box/WD repeat-containing protein 1A isoform X15

      See identical proteins and their annotated locations for XP_011245429.1

      UniProtKB/TrEMBL
      A0A286YDT6
      Conserved Domains (4) summary
      cd00200
      Location:204482
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:207242
      7WD40; WD40 repeat [structural motif]
      pfam12125
      Location:4078
      Beta-TrCP_D; D domain of beta-TrCP
      pfam12937
      Location:82129
      F-box-like
    26. XM_030250722.1XP_030106582.1  F-box/WD repeat-containing protein 1A isoform X15

      UniProtKB/TrEMBL
      A0A286YDT6
      Conserved Domains (4) summary
      cd00200
      Location:204482
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:207242
      7WD40; WD40 repeat [structural motif]
      pfam12125
      Location:4078
      Beta-TrCP_D; D domain of beta-TrCP
      pfam12937
      Location:82129
      F-box-like
    27. XM_011247121.4XP_011245423.1  F-box/WD repeat-containing protein 1A isoform X5

      Conserved Domains (4) summary
      cd00200
      Location:282560
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:285320
      7WD40; WD40 repeat [structural motif]
      pfam12125
      Location:118156
      Beta-TrCP_D; D domain of beta-TrCP
      pfam12937
      Location:160207
      F-box-like
    28. XM_006526615.3XP_006526678.1  F-box/WD repeat-containing protein 1A isoform X15

      See identical proteins and their annotated locations for XP_006526678.1

      UniProtKB/TrEMBL
      A0A286YDT6
      Related
      ENSMUSP00000153562.2, ENSMUST00000224478.2
      Conserved Domains (4) summary
      cd00200
      Location:204482
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:207242
      7WD40; WD40 repeat [structural motif]
      pfam12125
      Location:4078
      Beta-TrCP_D; D domain of beta-TrCP
      pfam12937
      Location:82129
      F-box-like
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