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    Vsnl1 visinin-like 1 [ Mus musculus (house mouse) ]

    Gene ID: 26950, updated on 9-Dec-2024

    Summary

    Official Symbol
    Vsnl1provided by MGI
    Official Full Name
    visinin-like 1provided by MGI
    Primary source
    MGI:MGI:1349453
    See related
    Ensembl:ENSMUSG00000054459 AllianceGenome:MGI:1349453
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    VILIP; Vnsl1
    Summary
    Predicted to enable calcium ion binding activity. Acts upstream of or within negative regulation of insulin secretion; positive regulation of exocytosis; and positive regulation of insulin secretion involved in cellular response to glucose stimulus. Located in cytosol and membrane. Is expressed in several structures, including alimentary system; brain; great vessel of heart; heart; and sensory organ. Orthologous to human VSNL1 (visinin like 1). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in cortex adult (RPKM 134.2), cerebellum adult (RPKM 127.1) and 3 other tissues See more
    Orthologs
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    Genomic context

    See Vsnl1 in Genome Data Viewer
    Location:
    12 A1.1; 12 5.58 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 12 NC_000078.7 (11375258..11486579, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 12 NC_000078.6 (11325257..11436578, complement)

    Chromosome 12 - NC_000078.7Genomic Context describing neighboring genes Neighboring gene GEN1, Holliday junction 5' flap endonuclease Neighboring gene STARR-positive B cell enhancer ABC_E8479 Neighboring gene structural maintenance of chromosomes 6 Neighboring gene STARR-seq mESC enhancer starr_31540 Neighboring gene microRNA 7675 Neighboring gene STARR-seq mESC enhancer starr_31541 Neighboring gene RIKEN cDNA 4930511A02 gene Neighboring gene RAD51 associated protein 2

    Genomic regions, transcripts, and products

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (3) 
    • Targeted (1) 

    Interactions

    General gene information

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables calcium ion binding  
    enables calcium ion binding  
    Component Evidence Code Pubs
    located_in cytosol PubMed 
    located_in membrane PubMed 

    General protein information

    Preferred Names
    visinin-like protein 1
    Names
    NVL-1
    NVP-1
    neural visinin-like protein 1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001378929.1NP_001365858.1  visinin-like protein 1

      Status: VALIDATED

      Source sequence(s)
      AC139207
      UniProtKB/Swiss-Prot
      P62761
      UniProtKB/TrEMBL
      Q3TVC0, Q4W4C9
      Related
      ENSMUSP00000152711.2, ENSMUST00000220506.2
      Conserved Domains (1) summary
      COG5126
      Location:15181
      FRQ1; Ca2+-binding protein, EF-hand superfamily [Signal transduction mechanisms]
    2. NM_012038.5NP_036168.1  visinin-like protein 1

      See identical proteins and their annotated locations for NP_036168.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript. Variants 1 and 2 both encode the same protein.
      Source sequence(s)
      AC139207
      Consensus CDS
      CCDS25816.1
      UniProtKB/Swiss-Prot
      P62761
      UniProtKB/TrEMBL
      Q3TVC0, Q4W4C9
      Related
      ENSMUSP00000072145.6, ENSMUST00000072299.7
      Conserved Domains (1) summary
      COG5126
      Location:15181
      FRQ1; Ca2+-binding protein, EF-hand superfamily [Signal transduction mechanisms]

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000078.7 Reference GRCm39 C57BL/6J

      Range
      11375258..11486579 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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