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rpl10 ribosomal protein L10 [ Danio rerio (zebrafish) ]

Gene ID: 336712, updated on 9-Dec-2024

Summary

Official Symbol
rpl10provided by ZNC
Official Full Name
ribosomal protein L10provided by ZNC
Primary source
ZFIN:ZDB-GENE-030131-8656
See related
Ensembl:ENSDARG00000025581 AllianceGenome:ZFIN:ZDB-GENE-030131-8656
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
QM; rpl-10; fa93d03; zgc:56154; QM protein; wu:fa93d03
Summary
Enables translation regulator activity. Involved in embryonic brain development and regulation of translation. Acts upstream of or within brain development. Predicted to be located in cytoplasm and ribosome. Predicted to be part of cytosolic large ribosomal subunit. Is expressed in head and midbrain hindbrain boundary. Human ortholog(s) of this gene implicated in autistic disorder; spermatogenic failure 63; and syndromic X-linked mental retardation 35. Orthologous to several human genes including RPL10 (ribosomal protein L10). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
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Genomic context

See rpl10 in Genome Data Viewer
Location:
chromosome: 23
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 23 NC_007134.7 (19712557..19715812, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 23 NC_007134.6 (19786213..19789471, complement)

Chromosome 23 - NC_007134.7Genomic Context describing neighboring genes Neighboring gene si:dkey-93l1.6 Neighboring gene deoxyribonuclease I-like 1 Neighboring gene small nucleolar RNA SNORA70 Neighboring gene small nucleolar RNA SNORA70 Neighboring gene filamin A, alpha (actin binding protein 280) Neighboring gene emerin

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Pathways from PubChem

General gene information

Gene Ontology Provided by ZFIN

Process Evidence Code Pubs
acts_upstream_of_or_within brain development PubMed 
involved_in embryonic brain development PubMed 
acts_upstream_of_or_within regulation of translation  
involved_in regulation of translation PubMed 
involved_in translation  
acts_upstream_of_or_within translation  
Component Evidence Code Pubs
located_in cytoplasm  
part_of cytosolic large ribosomal subunit  
part_of ribonucleoprotein complex  
located_in ribosome  

General protein information

Preferred Names
large ribosomal subunit protein uL16
Names
60S ribosomal protein L10
associated with tumor suppression, cell growth, differentiation, development and apoptosis
protein QM
NP_956321.1
XP_068072792.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_200027.1NP_956321.1  large ribosomal subunit protein uL16

    See identical proteins and their annotated locations for NP_956321.1

    Status: PROVISIONAL

    Source sequence(s)
    BC045950
    UniProtKB/Swiss-Prot
    Q7ZV96
    Related
    ENSDARP00000120909.1, ENSDART00000131860.3
    Conserved Domains (1) summary
    PTZ00173
    Location:1209
    PTZ00173; 60S ribosomal protein L10; Provisional

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007134.7 Reference GRCz11 Primary Assembly

    Range
    19712557..19715812 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_068216691.1XP_068072792.1  large ribosomal subunit protein uL16 isoform X1

    UniProtKB/Swiss-Prot
    Q7ZV96
    Related
    ENSDARP00000119262.1, ENSDART00000142072.3

Reference GRCz11 ALT_DRER_TU_1

Genomic

  1. NW_018395142.1 Reference GRCz11 ALT_DRER_TU_1

    Range
    40551..43805 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCz11 ALT_DRER_TU_2

Genomic

  1. NW_018395361.1 Reference GRCz11 ALT_DRER_TU_2

    Range
    256192..259532 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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