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Rpl27 ribosomal protein L27 [ Mus musculus (house mouse) ]

Gene ID: 19942, updated on 9-Dec-2024

Summary

Official Symbol
Rpl27provided by MGI
Official Full Name
ribosomal protein L27provided by MGI
Primary source
MGI:MGI:98036
See related
Ensembl:ENSMUSG00000063316 AllianceGenome:MGI:98036
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Summary
A structural constituent of ribosome. Predicted to be involved in rRNA processing. Located in cytoplasm. Part of cytosolic large ribosomal subunit. Is active in synapse. Is expressed in lower jaw molar; lower jaw tooth; tooth; and upper jaw incisor. Human ortholog(s) of this gene implicated in Diamond-Blackfan anemia 16. Orthologous to human RPL27 (ribosomal protein L27). [provided by Alliance of Genome Resources, Dec 2024]
Expression
Ubiquitous expression in liver E14 (RPKM 264.7), liver E14.5 (RPKM 220.0) and 28 other tissues See more
Orthologs
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Genomic context

See Rpl27 in Genome Data Viewer
Location:
11 D; 11 65.05 cM
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (101333071..101336422)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (101442245..101445596)

Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene prostaglandin E synthase 3 like Neighboring gene microRNA 6929 Neighboring gene STARR-positive B cell enhancer ABC_E596 Neighboring gene RUN domain containing 1 Neighboring gene STARR-positive B cell enhancer ABC_E1431 Neighboring gene STARR-positive B cell enhancer ABC_E7067 Neighboring gene STARR-seq mESC enhancer starr_30763 Neighboring gene interferon-induced protein 35 Neighboring gene vesicle amine transport 1

Genomic regions, transcripts, and products

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

Pathways from PubChem

Interactions

General gene information

Clone Names

  • MGC103134

Gene Ontology Provided by MGI

Process Evidence Code Pubs
involved_in cytoplasmic translation PubMed 
involved_in rRNA processing  
involved_in rRNA processing  
involved_in response to aldosterone  
involved_in translation at postsynapse PubMed 
involved_in translation at presynapse PubMed 
Component Evidence Code Pubs
located_in cytoplasm PubMed 
located_in cytoplasmic side of rough endoplasmic reticulum membrane  
located_in cytosol  
part_of cytosolic large ribosomal subunit  
part_of cytosolic large ribosomal subunit PubMed 
part_of cytosolic large ribosomal subunit PubMed 
part_of cytosolic large ribosomal subunit  
located_in cytosolic ribosome  
part_of large ribosomal subunit  
located_in nucleolus  
located_in nucleolus  
located_in nucleoplasm  
located_in nucleoplasm  
is_active_in postsynapse PubMed 
is_active_in presynapse PubMed 
part_of ribonucleoprotein complex PubMed 
located_in ribosome  
is_active_in ribosome PubMed 
is_active_in synapse PubMed 
is_active_in synapse PubMed 

General protein information

Preferred Names
large ribosomal subunit protein eL27
Names
60S ribosomal protein L27
NP_035419.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_011289.3NP_035419.1  large ribosomal subunit protein eL27

    See identical proteins and their annotated locations for NP_035419.1

    Status: VALIDATED

    Source sequence(s)
    AK132027, BQ748836, CN831363
    Consensus CDS
    CCDS25470.1
    UniProtKB/Swiss-Prot
    P61358
    UniProtKB/TrEMBL
    Q5BLJ9
    Related
    ENSMUSP00000090305.6, ENSMUST00000077856.13
    Conserved Domains (1) summary
    cl00354
    Location:1136
    KOW; an acronym for the authors' surnames (Kyrpides, Ouzounis and Woese)

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000077.7 Reference GRCm39 C57BL/6J

    Range
    101333071..101336422
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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