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GLOD5 glyoxalase domain containing 5 [ Homo sapiens (human) ]

Gene ID: 392465, updated on 10-Dec-2024

Summary

Official Symbol
GLOD5provided by HGNC
Official Full Name
glyoxalase domain containing 5provided by HGNC
Primary source
HGNC:HGNC:33358
See related
Ensembl:ENSG00000171433 MIM:301112; AllianceGenome:HGNC:33358
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This gene encodes a protein with a glyoxalase domain. [provided by RefSeq, Sep 2011]
Expression
Biased expression in duodenum (RPKM 3.2), small intestine (RPKM 2.9) and 6 other tissues See more
Orthologs
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Genomic context

See GLOD5 in Genome Data Viewer
Location:
Xp11.23
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) X NC_000023.11 (48761747..48773648)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) X NC_060947.1 (48172222..48184150)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) X NC_000023.10 (48620151..48632064)

Chromosome X - NC_000023.11Genomic Context describing neighboring genes Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 20820 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 20821 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 20822 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 29608 Neighboring gene SUV39H1 histone lysine methyltransferase Neighboring gene Sharpr-MPRA regulatory region 10462 Neighboring gene RNA, U6 small nuclear 1056, pseudogene Neighboring gene ATAC-STARR-seq lymphoblastoid active region 29609 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 29610 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 29611 Neighboring gene CRISPRi-FlowFISH-validated GATA1 regulatory element 1 Neighboring gene Sharpr-MPRA regulatory region 5097 Neighboring gene ACAA2 pseudogene 1 Neighboring gene RNA, U6 small nuclear 29, pseudogene Neighboring gene CRISPRi-validated e-GATA1 enhancer Neighboring gene CRISPRi-FlowFISH-validated GATA1, HDAC6 and PLP2 regulatory element 1 Neighboring gene CRISPRi-FlowFISH-validated HDAC6, PLP2 and PQBP1 regulatory element Neighboring gene CRISPRi-FlowFISH-validated PLP2 regulatory element 5 Neighboring gene CRISPRi-FlowFISH-validated PLP2 regulatory element 6 Neighboring gene CRISPRi-FlowFISH-validated PQBP1 regulatory element 1 Neighboring gene GATA binding protein 1

Genomic regions, transcripts, and products

Expression

  • Project title: Tissue-specific circular RNA induction during human fetal development
  • Description: 35 human fetal samples from 6 tissues (3 - 7 replicates per tissue) collected between 10 and 20 weeks gestational time were sequenced using Illumina TruSeq Stranded Total RNA
  • BioProject: PRJNA270632
  • Publication: PMID 26076956
  • Analysis date: Mon Apr 2 22:54:59 2018

Interactions

General protein information

Preferred Names
glyoxalase domain-containing protein 5

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_021291.2 RefSeqGene

    Range
    5002..16903
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001080489.3NP_001073958.2  glyoxalase domain-containing protein 5

    See identical proteins and their annotated locations for NP_001073958.2

    Status: REVIEWED

    Source sequence(s)
    AC231533, AI458936, BC067236, DY655159
    Consensus CDS
    CCDS55410.1
    UniProtKB/Swiss-Prot
    A6NK44
    Related
    ENSP00000302552.6, ENST00000303227.11
    Conserved Domains (1) summary
    cd07253
    Location:35157
    GLOD5; Human glyoxalase domain-containing protein 5 and similar proteins

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000023.11 Reference GRCh38.p14 Primary Assembly

    Range
    48761747..48773648
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060947.1 Alternate T2T-CHM13v2.0

    Range
    48172222..48184150
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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