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    emr-1 Emerin homolog 1 [ Caenorhabditis elegans ]

    Gene ID: 171752, updated on 9-Dec-2024

    Summary

    Official Symbol
    emr-1
    Official Full Name
    Emerin homolog 1
    Primary source
    WormBase:WBGene00001309
    Locus tag
    CELE_M01D7.6
    See related
    AllianceGenome:WB:WBGene00001309
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Enables lamin binding activity. Involved in several processes, including mitotic cytokinesis; nuclear envelope organization; and response to X-ray. Located in nuclear inner membrane. Is expressed in body wall musculature; intestine; nervous system; and pharynx. Used to study Emery-Dreifuss muscular dystrophy. Orthologous to human LEMD1 (LEM domain containing 1). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

    See emr-1 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    3
    Sequence:
    Chromosome: I; NC_003279.8 (1842445..1843227)

    Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene Guanine nucleotide-binding protein subunit alpha Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Neuropeptide-Like Protein Neighboring gene GHMP kinase C-terminal domain-containing protein;Galactokinase

    Bibliography

    Interactions

    General gene information

    Gene Ontology Provided by WormBase

    Process Evidence Code Pubs
    involved_in cell cycle  
    involved_in chromosome segregation PubMed 
    involved_in mitotic cytokinesis PubMed 
    involved_in nuclear envelope organization PubMed 
    involved_in response to X-ray PubMed 
    Component Evidence Code Pubs
    located_in membrane  
    located_in nuclear envelope PubMed 
    located_in nuclear envelope  
    located_in nuclear inner membrane PubMed 
    located_in nuclear inner membrane  
    located_in nucleus  

    General protein information

    Preferred Names
    Emerin homolog 1
    NP_490907.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003279.8 Reference assembly

      Range
      1842445..1843227
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_058506.6NP_490907.1  Emerin homolog 1 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_490907.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O01971
      Conserved Domains (1) summary
      pfam03020
      Location:240
      LEM; LEM domain
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