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R09H10.3 putative 5-hydroxyisourate hydrolase R09H10.3 [ Caenorhabditis elegans ]

Gene ID: 187757, updated on 9-Dec-2024

Summary

Official Symbol
R09H10.3
Official Full Name
putative 5-hydroxyisourate hydrolase R09H10.3
Primary source
WormBase:WBGene00011181
Locus tag
CELE_R09H10.3
See related
AllianceGenome:WB:WBGene00011181
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Enables identical protein binding activity. Predicted to be involved in purine nucleobase metabolic process. Human ortholog(s) of this gene implicated in Alzheimer's disease; amyloidosis; carpal tunnel syndrome 1; dystransthyretinemic hyperthyroxinemia; and transthyretin amyloidosis. Orthologous to human TTR (transthyretin). [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

See R09H10.3 in Genome Data Viewer
Location:
chromosome: IV
Exon count:
3
Sequence:
Chromosome: IV; NC_003282.8 (10607030..10608428)

Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene Methyltransferase FkbM domain-containing protein Neighboring gene ncRNA Neighboring gene Methyltransferase FkbM domain-containing protein Neighboring gene EF-hand domain-containing protein Neighboring gene ncRNA Neighboring gene ncRNA

Interactions

General gene information

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables hydrolase activity  
enables hydroxyisourate hydrolase activity  
enables identical protein binding PubMed 
enables protein binding PubMed 

General protein information

Preferred Names
putative 5-hydroxyisourate hydrolase R09H10.3
NP_001040980.1
  • Confirmed by transcript evidence
NP_001040981.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003282.8 Reference assembly

    Range
    10607030..10608428
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001047515.6NP_001040980.1  putative 5-hydroxyisourate hydrolase R09H10.3 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001040980.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q1NZ16, Q21882
    Conserved Domains (1) summary
    TIGR02962
    Location:25135
    hdxy_isourate; hydroxyisourate hydrolase
  2. NM_001047516.5NP_001040981.1  putative 5-hydroxyisourate hydrolase R09H10.3 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001040981.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q21882
    Conserved Domains (1) summary
    TIGR02962
    Location:11121
    hdxy_isourate; hydroxyisourate hydrolase
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