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Full record GDS4817

SIRT3 deficient liver response to a high fat diet

Analysis of livers of mitochondrial protein deacetylase SIRT3 null mutants on a high fat diet (HFD). SIRT3 null mutants on a HFD exhibit obesity, insulin resistance, hyperlipidemia, and steatohepatitis. Results provide insight into molecular basis of metabolic dysfunction in SIRT3-deficient livers.
Organism:
Mus musculus
Type:
Expression profiling by array, transformed count, 2 genotype/variation, 2 protocol sets
Platform:
GPL6246
Series:
GSE30552
12 Samples
Download data: CEL

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