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    Slco6c1 solute carrier organic anion transporter family, member 6c1 [ Mus musculus (house mouse) ]

    Gene ID: 74441, updated on 9-Dec-2024

    Summary

    Official Symbol
    Slco6c1provided by MGI
    Official Full Name
    solute carrier organic anion transporter family, member 6c1provided by MGI
    Primary source
    MGI:MGI:1921691
    See related
    Ensembl:ENSMUSG00000026331 AllianceGenome:MGI:1921691
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    4933404A18Rik
    Summary
    Predicted to enable sodium-independent organic anion transmembrane transporter activity. Predicted to be involved in sodium-independent organic anion transport. Part of CatSper complex. Orthologous to human SLCO6A1 (solute carrier organic anion transporter family member 6A1). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Restricted expression toward testis adult (RPKM 16.6) See more
    Orthologs
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    Genomic context

    See Slco6c1 in Genome Data Viewer
    Location:
    1 D; 1 47.76 cM
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 1 NC_000067.7 (96986763..97056066, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 1 NC_000067.6 (97059038..97128339, complement)

    Chromosome 1 - NC_000067.7Genomic Context describing neighboring genes Neighboring gene glyceraldehyde-3-phosphate dehydrogenase pseudogene Neighboring gene heterogeneous nuclear ribonucleoprotein F pseudogene Neighboring gene STARR-seq mESC enhancer starr_01773 Neighboring gene STARR-seq mESC enhancer starr_01774 Neighboring gene predicted gene 7133 Neighboring gene STARR-seq mESC enhancer starr_01775 Neighboring gene predicted gene 7135 Neighboring gene STARR-seq mESC enhancer starr_01776 Neighboring gene STARR-seq mESC enhancer starr_01777

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    General gene information

    Gene Ontology Provided by MGI

    Component Evidence Code Pubs
    part_of CatSper complex PubMed 
    is_active_in basolateral plasma membrane  
    located_in motile cilium  
    located_in plasma membrane  

    General protein information

    Preferred Names
    solute carrier organic anion transporter family member 6C1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_028942.4NP_083218.1  solute carrier organic anion transporter family member 6C1

      See identical proteins and their annotated locations for NP_083218.1

      Status: PROVISIONAL

      Source sequence(s)
      AK029505
      Consensus CDS
      CCDS35677.1
      UniProtKB/Swiss-Prot
      Q3V161, Q8C0X7, Q9D4B7
      Related
      ENSMUSP00000027569.8, ENSMUST00000027569.14
      Conserved Domains (3) summary
      cd06174
      Location:97463
      MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
      cd01330
      Location:487540
      KAZAL_SLC21; The kazal-type serine protease inhibitor domain has been detected in an extracellular loop region of solute carrier 21 (SLC21) family members (organic anion transporters) , which may regulate the specificity of anion uptake. The KAZAL_SLC21 domain is a ...
      pfam03137
      Location:95654
      OATP; Organic Anion Transporter Polypeptide (OATP) family

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000067.7 Reference GRCm39 C57BL/6J

      Range
      96986763..97056066 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006529913.5XP_006529976.1  solute carrier organic anion transporter family member 6C1 isoform X1

      Conserved Domains (1) summary
      cl28910
      Location:93544
      MFS; Major Facilitator Superfamily
    2. XM_006529914.3XP_006529977.1  solute carrier organic anion transporter family member 6C1 isoform X2

      Conserved Domains (1) summary
      cl28910
      Location:10243
      MFS; Major Facilitator Superfamily
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