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    Scrg1 scrapie responsive gene 1 [ Mus musculus (house mouse) ]

    Gene ID: 20284, updated on 9-Dec-2024

    Summary

    Official Symbol
    Scrg1provided by MGI
    Official Full Name
    scrapie responsive gene 1provided by MGI
    Primary source
    MGI:MGI:1328308
    See related
    Ensembl:ENSMUSG00000031610 AllianceGenome:MGI:1328308
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Summary
    Predicted to be involved in mesenchymal stem cell proliferation. Located in Golgi apparatus and neuron projection terminus. Is expressed in several structures, including central nervous system; cranium; foot bone; lung; and sternum. Orthologous to human SCRG1 (stimulator of chondrogenesis 1). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in cortex adult (RPKM 8.4), frontal lobe adult (RPKM 7.3) and 6 other tissues See more
    Orthologs
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    Genomic context

    See Scrg1 in Genome Data Viewer
    Location:
    8 B2; 8 29.8 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 8 NC_000074.7 (57909093..57932441)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 8 NC_000074.6 (57455882..57479360)

    Chromosome 8 - NC_000074.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_21526 Neighboring gene predicted gene, 34099 Neighboring gene mannosidase 2, alpha 2 pseudogene Neighboring gene STARR-seq mESC enhancer starr_21527 Neighboring gene RIKEN cDNA 2500002B13 gene Neighboring gene STARR-positive B cell enhancer ABC_E1755 Neighboring gene STARR-seq mESC enhancer starr_21528 Neighboring gene sin3 associated polypeptide

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Interactions

    General gene information

    Gene Ontology Provided by MGI

    Component Evidence Code Pubs
    is_active_in Golgi apparatus  
    located_in Golgi apparatus PubMed 
    located_in cytoplasm PubMed 
    located_in extracellular region  
    is_active_in neuron projection terminus  
    located_in neuron projection terminus PubMed 

    General protein information

    Preferred Names
    scrapie-responsive protein 1
    Names
    scRG-1
    scrapie responsive protein one
    scrapie-responsive gene 1 protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001424875.1NP_001411804.1  scrapie-responsive protein 1 precursor

      Status: VALIDATED

      Source sequence(s)
      AC128700, AC130841
      UniProtKB/Swiss-Prot
      O88745
      UniProtKB/TrEMBL
      Q543T5
    2. NM_009136.4NP_033162.1  scrapie-responsive protein 1 precursor

      See identical proteins and their annotated locations for NP_033162.1

      Status: VALIDATED

      Source sequence(s)
      AC128700, AC130841
      Consensus CDS
      CCDS40342.1
      UniProtKB/Swiss-Prot
      O88745
      UniProtKB/TrEMBL
      Q543T5
      Related
      ENSMUSP00000034023.4, ENSMUST00000034023.4
      Conserved Domains (1) summary
      pfam15224
      Location:2297
      SCRG1; Scrapie-responsive protein 1

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000074.7 Reference GRCm39 C57BL/6J

      Range
      57909093..57932441
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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