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Tssk5 testis-specific serine kinase 5 [ Mus musculus (house mouse) ]

Gene ID: 73542, updated on 9-Dec-2024

Summary

Official Symbol
Tssk5provided by MGI
Official Full Name
testis-specific serine kinase 5provided by MGI
Primary source
MGI:MGI:1920792
See related
Ensembl:ENSMUSG00000060794 AllianceGenome:MGI:1920792
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
TSK-5; 1700091F14Rik
Summary
Predicted to enable ATP binding activity; magnesium ion binding activity; and protein serine/threonine kinase activity. Predicted to be involved in protein phosphorylation. Is expressed in metanephros; submandibular gland; and testis. Orthologous to human TSSK5P (testis specific serine kinase 5, pseudogene). [provided by Alliance of Genome Resources, Dec 2024]
Expression
Restricted expression toward testis adult (RPKM 21.6) See more
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Genomic context

See Tssk5 in Genome Data Viewer
Location:
15 D3; 15 35.79 cM
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 15 NC_000081.7 (76256158..76259391, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 15 NC_000081.6 (76371958..76375191, complement)

Chromosome 15 - NC_000081.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_39052 Neighboring gene WD repeat domain 97 Neighboring gene STARR-positive B cell enhancer ABC_E11592 Neighboring gene STARR-positive B cell enhancer ABC_E1912 Neighboring gene HGH1 homolog Neighboring gene maestro heat-like repeat family member 1 Neighboring gene microRNA 6954 Neighboring gene block of proliferation 1 Neighboring gene scleraxis scleraxis bHLH transcription factor

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (2) 

Interactions

General gene information

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables 3-phosphoinositide-dependent protein kinase activity  
enables AMP-activated protein kinase activity  
enables ATP binding  
enables DNA-dependent protein kinase activity  
enables Rho-dependent protein serine/threonine kinase activity  
enables eukaryotic translation initiation factor 2alpha kinase activity  
enables histone H2AS1 kinase activity  
enables histone H2AS121 kinase activity  
enables histone H2AT120 kinase activity  
enables histone H2AXS139 kinase activity  
enables histone H2BS14 kinase activity  
enables histone H2BS36 kinase activity  
enables histone H3S10 kinase activity  
enables histone H3S28 kinase activity  
enables histone H3S57 kinase activity  
enables histone H3T11 kinase activity  
enables histone H3T3 kinase activity  
enables histone H3T45 kinase activity  
enables histone H3T6 kinase activity  
enables histone H4S1 kinase activity  
enables magnesium ion binding  
enables protein serine kinase activity  
enables protein serine/threonine kinase activity  
enables protein serine/threonine kinase activity  
enables ribosomal protein S6 kinase activity  
Process Evidence Code Pubs
involved_in cell differentiation  
involved_in chromatin remodeling  
involved_in protein phosphorylation  
involved_in spermatogenesis  

General protein information

Preferred Names
testis-specific serine/threonine-protein kinase 5
Names
testis-specific kinase 5
NP_898922.2
XP_011244046.1
XP_011244047.1
XP_011244048.1
XP_011244049.1
XP_011244050.1
XP_017172248.1
XP_030104654.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_183099.2NP_898922.2  testis-specific serine/threonine-protein kinase 5

    See identical proteins and their annotated locations for NP_898922.2

    Status: VALIDATED

    Source sequence(s)
    AK007032, BC114543
    Consensus CDS
    CCDS37122.1
    UniProtKB/Swiss-Prot
    Q1WWK7, Q8C1R0
    Related
    ENSMUSP00000071120.7, ENSMUST00000071119.8
    Conserved Domains (2) summary
    smart00220
    Location:31302
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    cl21453
    Location:26301
    PKc_like; Protein Kinases, catalytic domain

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000081.7 Reference GRCm39 C57BL/6J

    Range
    76256158..76259391 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_030248794.1XP_030104654.1  testis-specific serine/threonine-protein kinase 5 isoform X4

    Conserved Domains (1) summary
    cl21453
    Location:2236
    PKc_like; Protein Kinases, catalytic domain
  2. XM_017316759.2XP_017172248.1  testis-specific serine/threonine-protein kinase 5 isoform X2

    Conserved Domains (1) summary
    cl21453
    Location:26254
    PKc_like; Protein Kinases, catalytic domain
  3. XM_011245744.3XP_011244046.1  testis-specific serine/threonine-protein kinase 5 isoform X1

    Conserved Domains (1) summary
    cl21453
    Location:26301
    PKc_like; Protein Kinases, catalytic domain
  4. XM_011245745.3XP_011244047.1  testis-specific serine/threonine-protein kinase 5 isoform X3

    Conserved Domains (1) summary
    cl21453
    Location:26295
    PKc_like; Protein Kinases, catalytic domain
  5. XM_011245748.3XP_011244050.1  testis-specific serine/threonine-protein kinase 5 isoform X5

    See identical proteins and their annotated locations for XP_011244050.1

    Conserved Domains (1) summary
    cl21453
    Location:26235
    PKc_like; Protein Kinases, catalytic domain
  6. XM_011245746.3XP_011244048.1  testis-specific serine/threonine-protein kinase 5 isoform X5

    See identical proteins and their annotated locations for XP_011244048.1

    Conserved Domains (1) summary
    cl21453
    Location:26235
    PKc_like; Protein Kinases, catalytic domain
  7. XM_011245747.3XP_011244049.1  testis-specific serine/threonine-protein kinase 5 isoform X6

    Conserved Domains (1) summary
    cl21453
    Location:26237
    PKc_like; Protein Kinases, catalytic domain

RNA

  1. XR_875314.3 RNA Sequence

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