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    Prelid1 PRELI domain containing 1 [ Mus musculus (house mouse) ]

    Gene ID: 66494, updated on 9-Dec-2024

    Summary

    Official Symbol
    Prelid1provided by MGI
    Official Full Name
    PRELI domain containing 1provided by MGI
    Primary source
    MGI:MGI:1913744
    See related
    Ensembl:ENSMUSG00000021486 AllianceGenome:MGI:1913744
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Preli; 2610524G07Rik
    Summary
    Predicted to enable phosphatidic acid transfer activity. Involved in negative regulation of apoptotic process. Located in mitochondrion. Is expressed in several structures, including brain; gonad; immune system; liver; and stomach. Orthologous to human PRELID1 (PRELI domain containing 1). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Ubiquitous expression in duodenum adult (RPKM 465.5), large intestine adult (RPKM 374.9) and 27 other tissues See more
    Orthologs
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    Genomic context

    See Prelid1 in Genome Data Viewer
    Location:
    13 B1; 13 29.8 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 13 NC_000079.7 (55469868..55473085)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 13 NC_000079.6 (55322055..55325272)

    Chromosome 13 - NC_000079.7Genomic Context describing neighboring genes Neighboring gene nuclear receptor-binding SET-domain protein 1 Neighboring gene STARR-seq mESC enhancer starr_34609 Neighboring gene CapStarr-seq enhancer MGSCv37_chr13:55429152-55429261 Neighboring gene RAB24, member RAS oncogene family Neighboring gene STARR-seq mESC enhancer starr_34614 Neighboring gene Max dimerization protein 3 Neighboring gene lectin, mannose-binding 2 Neighboring gene STARR-positive B cell enhancer ABC_E7242 Neighboring gene CapStarr-seq enhancer MGSCv37_chr13:55471008-55471191 Neighboring gene CapStarr-seq enhancer MGSCv37_chr13:55475647-55475848 Neighboring gene regulator of G-protein signaling 14

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    General gene information

    Gene Ontology Provided by MGI

    Process Evidence Code Pubs
    involved_in apoptotic process  
    involved_in intermembrane lipid transfer  
    involved_in negative regulation of apoptotic process PubMed 
    involved_in negative regulation of apoptotic process  
    involved_in negative regulation of mitochondrial membrane potential  
    involved_in negative regulation of mitochondrial membrane potential  
    involved_in negative regulation of release of cytochrome c from mitochondria  
    involved_in negative regulation of release of cytochrome c from mitochondria  
    involved_in phospholipid transport  
    involved_in phospholipid transport  
    involved_in positive regulation of T cell apoptotic process  
    involved_in positive regulation of T cell apoptotic process  
    involved_in positive regulation of cellular respiration  
    involved_in positive regulation of cellular respiration  
    involved_in positive regulation of endopeptidase activity  
    involved_in positive regulation of endopeptidase activity  
    involved_in positive regulation of phospholipid transport  
    involved_in positive regulation of phospholipid transport  
    involved_in regulation of T cell differentiation  
    involved_in regulation of T cell differentiation  
    involved_in regulation of membrane lipid distribution  
    involved_in regulation of membrane lipid distribution  
    involved_in regulation of mitochondrial membrane potential  
    involved_in regulation of mitochondrial membrane potential  
    Component Evidence Code Pubs
    is_active_in mitochondrial intermembrane space  
    located_in mitochondrial intermembrane space  
    located_in mitochondrial intermembrane space  
    located_in mitochondrion PubMed 
    located_in mitochondrion  
    located_in nucleoplasm  
    located_in nucleoplasm  
    part_of protein-containing complex  
    part_of protein-containing complex  

    General protein information

    Preferred Names
    PRELI domain-containing protein 1, mitochondrial
    Names
    PX19 homolog
    protein of relevant evolutionary and lymphoid interest
    px19-like protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_025596.5NP_079872.4  PRELI domain-containing protein 1, mitochondrial precursor

      See identical proteins and their annotated locations for NP_079872.4

      Status: PROVISIONAL

      Source sequence(s)
      BC025859
      Consensus CDS
      CCDS26542.1
      UniProtKB/Swiss-Prot
      Q3UCN0, Q4QQJ9, Q6PCZ5, Q78IE2, Q8R107, Q9D1F7
      Related
      ENSMUSP00000021942.7, ENSMUST00000021942.8
      Conserved Domains (1) summary
      pfam04707
      Location:16172
      PRELI; PRELI-like family

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000079.7 Reference GRCm39 C57BL/6J

      Range
      55469868..55473085
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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