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Full record GDS4096

Mutant p53 depletion effect on MDA-468.shp53 breast tumor cell line

Analysis of MDA-468.shp53 cells cultured under 3D conditions in the presence of DOX. These cells express a DOX-inducible shRNA targeting endogenous mutant p53. The p53-reduced cells have an invasive, highly disorganized appearance. Results provide insight into role of mutant p53 in breast cancer.
Organism:
Homo sapiens
Type:
Expression profiling by array, transformed count, 2 growth protocol sets
Platform:
GPL6244
Series:
GSE31812
6 Samples
Download data: CEL

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