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Snap29 synaptosome associated protein 29 [ Rattus norvegicus (Norway rat) ]

Gene ID: 116500, updated on 9-Dec-2024

Summary

Official Symbol
Snap29provided by RGD
Official Full Name
synaptosome associated protein 29provided by RGD
Primary source
RGD:620225
See related
EnsemblRapid:ENSRNOG00000001867 AllianceGenome:RGD:620225
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Gs32
Summary
Predicted to enable SNAP receptor activity and syntaxin binding activity. Involved in regulation of synaptic vesicle cycle and regulation of synaptic vesicle exocytosis. Located in terminal bouton. Is active in synaptic vesicle. Is extrinsic component of synaptic vesicle membrane. Human ortholog(s) of this gene implicated in CEDNIK syndrome. Orthologous to human SNAP29 (synaptosome associated protein 29). [provided by Alliance of Genome Resources, Dec 2024]
Expression
Biased expression in Spleen (RPKM 177.6), Thymus (RPKM 151.9) and 9 other tissues See more
Orthologs
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Genomic context

See Snap29 in Genome Data Viewer
Location:
11q23
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 11 NC_086029.1 (97082721..97113195, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 11 NC_051346.1 (83578479..83608953, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 11 NC_005110.4 (87827633..87858107, complement)

Chromosome 11 - NC_086029.1Genomic Context describing neighboring genes Neighboring gene CRK like proto-oncogene, adaptor protein Neighboring gene transfer RNA serine (anticodon UGA) 1 Neighboring gene uncharacterized LOC134481103 Neighboring gene phosphatidylinositol 4-kinase alpha Neighboring gene serpin family D member 1

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

General gene information

Clone Names

  • MGC105273

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables SNAP receptor activity  
enables protein binding PubMed 
enables syntaxin binding  
Process Evidence Code Pubs
involved_in autophagosome maturation  
involved_in autophagosome maturation  
involved_in autophagosome membrane docking  
involved_in autophagosome membrane docking  
involved_in cilium assembly  
involved_in cilium assembly  
involved_in cilium assembly  
involved_in exocytosis  
involved_in protein transport  
involved_in regulation of synaptic vesicle cycle PubMed 
involved_in regulation of synaptic vesicle cycle PubMed 
involved_in regulation of synaptic vesicle exocytosis PubMed 
involved_in regulation of synaptic vesicle exocytosis PubMed 
involved_in synaptic vesicle fusion to presynaptic active zone membrane  
involved_in synaptic vesicle priming  
Items 1 - 20 of 22
Component Evidence Code Pubs
located_in Golgi membrane  
part_of SNARE complex  
part_of SNARE complex  
part_of SNARE complex  
part_of SNARE complex  
located_in autophagosome  
located_in autophagosome  
located_in autophagosome membrane  
located_in centrosome  
located_in centrosome  
located_in ciliary pocket membrane  
located_in ciliary pocket membrane  
located_in ciliary pocket membrane  
located_in cytoplasm  
located_in cytosol  
located_in cytosol  
is_active_in extrinsic component of synaptic vesicle membrane PubMed 
is_active_in extrinsic component of synaptic vesicle membrane PubMed 
located_in mitochondrion PubMed 
is_active_in plasma membrane  
is_active_in synaptic vesicle PubMed 
located_in terminal bouton PubMed 
Items 1 - 20 of 22

General protein information

Preferred Names
synaptosomal-associated protein 29
Names
SNAP-29
golgi SNARE of 32 kDa
soluble 29 kDa NSF attachment protein
synaptosomal-associated protein, 29kD
vesicle-membrane fusion protein SNAP-29

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_053810.3NP_446262.3  synaptosomal-associated protein 29

    See identical proteins and their annotated locations for NP_446262.3

    Status: PROVISIONAL

    Source sequence(s)
    BC091693
    UniProtKB/TrEMBL
    F7FPA1, Q5BIZ8, Q9JI56
    Related
    ENSRNOP00000002550.5, ENSRNOT00000002550.9
    Conserved Domains (2) summary
    cd15856
    Location:198256
    SNARE_SNAP29C; C-terminal SNARE motif of SNAP29
    cd15887
    Location:47111
    SNARE_SNAP29N; N-terminal SNARE motif of SNAP29

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086029.1 Reference GRCr8

    Range
    97082721..97113195 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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