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Select item 68225141.

The Diverse Functional Roles of Elongation Factor Tu (EF-Tu) in Microbial Pathogenesis

Kate L. Harvey, Veronica M. Jarocki, Ian G. Charles, Steven P. Djordjevic

Front Microbiol. 2019; 10: 2351. Published online 2019 Oct 24. doi: 10.3389/fmicb.2019.02351

PMCID:: PMC6822514

Article PDF–2.1M

Select item 67899082.

Highly efficient DSB-free base editing for streptomycetes with CRISPR-BEST

Yaojun Tong, Christopher M. Whitford, Helene L. Robertsen, Kai Blin, Tue S. Jørgensen, Andreas K. Klitgaard, Tetiana Gren, Xinglin Jiang, Tilmann Weber, Sang Yup Lee

Proc Natl Acad Sci U S A. 2019 Oct 8; 116(41): 20366–20375. Published online 2019 Sep 23. doi: 10.1073/pnas.1913493116

PMCID:: PMC6789908

Article PDF–2.4M

Select item 67842203.

Regulation of Geldanamycin Biosynthesis by Cluster-Situated Transcription Factors and the Master Regulator PhoP

Juan F. Martín, Angelina Ramos, Paloma Liras

Antibiotics (Basel) 2019 Sep; 8(3): 87. Published online 2019 Jun 30. doi: 10.3390/antibiotics8030087

PMCID:: PMC6784220

Article PDF–988K

Select item 64700284.

Structural and Functional Studies of a gem-Dimethylating Methyltransferase from a trans-Acyltransferase Assembly Line

Jessica L. Meinke, M. Rachel Mehaffey, Drew T. Wagner, Ningze Sun, Zhicheng Zhang, Jennifer S. Brodbelt, Adrian T. Keatinge-Clay

ACS Chem Biol. Author manuscript; available in PMC 2019 Apr 17.

Published in final edited form as: ACS Chem Biol. 2018 Dec 21; 13(12): 3306–3314. Published online 2018 Nov 9. doi: 10.1021/acschembio.8b00733

PMCID:: PMC6470028

Article PDF–3.0M

Select item 63774825.

Zn-dependent bifunctional proteases are responsible for leader peptide processing of class III lanthipeptides

Shaoming Chen, Bing Xu, Erquan Chen, Jiaqi Wang, Jingxia Lu, Stefano Donadio, Huiming Ge, Huan Wang

Proc Natl Acad Sci U S A. 2019 Feb 12; 116(7): 2533–2538. Published online 2019 Jan 24. doi: 10.1073/pnas.1815594116

PMCID:: PMC6377482

Article PDF–1.2M

Select item 62733836.

Self-resistance in Streptomyces, with Special Reference to β-Lactam Antibiotics

Hiroshi Ogawara

Molecules. 2016 May; 21(5): 605. Published online 2016 May 10. doi: 10.3390/molecules21050605

PMCID:: PMC6273383

Article PDF–6.8M

Select item 62449507.

Nitroalkanes as Central Reagents in the Synthesis of Spiroketals

Roberto Ballini, Marino Petrini, Goffredo Rosini

Molecules. 2008 Feb; 13(2): 319–330. Published online 2008 Feb 7. doi: 10.3390/molecules13020319

PMCID:: PMC6244950

Article PDF–89K

Select item 61766358.

Amycomicin is a potent and specific antibiotic discovered with a targeted interaction screen

Gleb Pishchany, Emily Mevers, Sula Ndousse-Fetter, Dennis J. Horvath, Jr., Camila R. Paludo, Eduardo A. Silva-Junior, Sergey Koren, Eric P. Skaar, Jon Clardy, Roberto Kolter

Proc Natl Acad Sci U S A. 2018 Oct 2; 115(40): 10124–10129. Published online 2018 Sep 18. doi: 10.1073/pnas.1807613115

PMCID:: PMC6176635

Article PDF–1.3M

Select item 61743459.

New Cytotoxic Cyclic Peptide from the Marine Sponge-Associated Nocardiopsis sp. UR67

Alyaa Hatem Ibrahim, Eman Zekry Attia, Dina Hajjar, Mohamed A. Anany, Samar Yehia Desoukey, Mostafa Ahmed Fouad, Mohamed Salah Kamel, Harald Wajant, Tobias A. M. Gulder, Usama Ramadan Abdelmohsen

Mar Drugs. 2018 Sep; 16(9): 290. Published online 2018 Aug 21. doi: 10.3390/md16090290

PMCID:: PMC6174345

Article PDF–1.0M

Select item 616587610.

Streptomyces as a Prominent Resource of Future Anti-MRSA Drugs

Hefa Mangzira Kemung, Loh Teng-Hern Tan, Tahir Mehmood Khan, Kok-Gan Chan, Priyia Pusparajah, Bey-Hing Goh, Learn-Han Lee

Front Microbiol. 2018; 9: 2221. Published online 2018 Sep 24. doi: 10.3389/fmicb.2018.02221

PMCID:: PMC6165876

Article PDF–2.0M

Select item 616487111.

Acyltransferases as Tools for Polyketide Synthase Engineering

Ewa Maria Musiol-Kroll, Wolfgang Wohlleben

Antibiotics (Basel) 2018 Sep; 7(3): 62. Published online 2018 Jul 18. doi: 10.3390/antibiotics7030062

PMCID:: PMC6164871

Article PDF–2.0M

Select item 610023712.

Isolation of β-1,3-Glucanase-Producing Microorganisms from Poria cocos Cultivation Soil via Molecular Biology

Qiulan Wu, Xin Dou, Qi Wang, Zhengbing Guan, Yujie Cai, Xiangru Liao

Molecules. 2018 Jul; 23(7): 1555. Published online 2018 Jun 27. doi: 10.3390/molecules23071555

PMCID:: PMC6100237

Article PDF–4.4M

Select item 609250513.

Diversity and Applications of Endophytic Actinobacteria of Plants in Special and Other Ecological Niches

Radha Singh, Ashok K. Dubey

Front Microbiol. 2018; 9: 1767. Published online 2018 Aug 8. doi: 10.3389/fmicb.2018.01767

PMCID:: PMC6092505

Article PDF–2.9M

Select item 609249414.

Heterologous Production of Microbial Ribosomally Synthesized and Post-translationally Modified Peptides

Yi Zhang, Manyun Chen, Steven D. Bruner, Yousong Ding

Front Microbiol. 2018; 9: 1801. Published online 2018 Aug 7. doi: 10.3389/fmicb.2018.01801

PMCID:: PMC6092494

Article PDF–1.9M

Select item 605818015.

Streptomyces nigra sp. nov. Is a Novel Actinobacterium Isolated From Mangrove Soil and Exerts a Potent Antitumor Activity in Vitro

Can Chen, Yanghui Ye, Ruijun Wang, Yinglao Zhang, Chen Wu, Sanjit C. Debnath, Zhongjun Ma, Jidong Wang, Min Wu

Front Microbiol. 2018; 9: 1587. Published online 2018 Jul 18. doi: 10.3389/fmicb.2018.01587

PMCID:: PMC6058180

Article PDF–1.0M

Select item 599285316.

Manipulation of two regulatory genes for efficient production of chromomycins in Streptomyces reseiscleroticus

Lei Sun, Jia Zeng, Peiwu Cui, Wei Wang, Dayu Yu, Jixun Zhan

J Biol Eng. 2018; 12: 9. Published online 2018 Jun 7. doi: 10.1186/s13036-018-0103-x

PMCID:: PMC5992853

Article PDF–1.1M

Select item 590196317.

The Lysosomal Potassium Channel TMEM175 Adopts a Novel Tetrameric Architecture

Changkeun Lee, Jiangtao Guo, Weizhong Zeng, Sunghoon Kim, Ji She, Chunlei Cang, Dejian Ren, Youxing Jiang

Nature. Author manuscript; available in PMC 2018 Apr 16.

Published in final edited form as: Nature. 2017 Jul 27; 547(7664): 472–475. Published online 2017 Jul 19. doi: 10.1038/nature23269

PMCID:: PMC5901963

Article PDF–1.6M

Select item 581848318.

Filling the Gaps in the Kirromycin Biosynthesis: Deciphering the Role of Genes Involved in Ethylmalonyl-CoA Supply and Tailoring Reactions

Helene L. Robertsen, Ewa M. Musiol-Kroll, Ling Ding, Kristina J. Laiple, Torben Hofeditz, Wolfgang Wohlleben, Sang Yup Lee, Stephanie Grond, Tilmann Weber

Sci Rep. 2018; 8: 3230. Published online 2018 Feb 19. doi: 10.1038/s41598-018-21507-6