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Ultrahigh Resolution Crystal Structures of Human Carbonic Anhydrases I and II Complexed with “Two-Prong” Inhibitors Reveal the Molecular Basis of High Affinity

Kevin M. Jude, Abir L. Banerjee, Manas K. Haldar, Sumathra Manokaran, Bidhan Roy, Sanku Mallik, D. K. Srivastava, David W. Christianson

J Am Chem Soc. Author manuscript; available in PMC 2008 Sep 1.

Published in final edited form as: J Am Chem Soc. 2006 Mar 8; 128(9): 3011–3018. doi: 10.1021/ja057257n

PMCID:: PMC2527509

Abstract Article PDF–1.8M

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