PMC Links for Protein (Select 4507609) - PMC

Select item 63692891.

Crystal structure of the m4-1BB/4-1BBL complex reveals an unusual dimeric ligand that undergoes structural changes upon 4-1BB receptor binding

Aruna Bitra, Tzanko Doukov, Giuseppe Destito, Michael Croft, Dirk M. Zajonc

J Biol Chem. 2019 Feb 8; 294(6): 1831–1845. Published online 2018 Dec 13. doi: 10.1074/jbc.RA118.006297

PMCID:: PMC6369289

Abstract Article PDF–4.4M

Select item 60289742.

Crystal structures of the human 4-1BB receptor bound to its ligand 4-1BBL reveal covalent receptor dimerization as a potential signaling amplifier

Aruna Bitra, Tzanko Doukov, Michael Croft, Dirk M. Zajonc

J Biol Chem. 2018 Jun 29; 293(26): 9958–9969. Published online 2018 May 2. doi: 10.1074/jbc.RA118.003176

PMCID:: PMC6028974

Abstract Article PDF–3.0M

Select item 55875853.

Identification of a p53 target, CD137L, that mediates growth suppression and immune response of osteosarcoma cells

Yusuke Tsuda, Chizu Tanikawa, Takafumi Miyamoto, Makoto Hirata, Varalee Yodsurang, Yao-zhong Zhang, Seiya Imoto, Rui Yamaguchi, Satoru Miyano, Hiroshi Takayanagi, Hirotaka Kawano, Hidewaki Nakagawa, Sakae Tanaka, Koichi Matsuda

Sci Rep. 2017; 7: 10739. Published online 2017 Sep 6. doi: 10.1038/s41598-017-11208-x

PMCID:: PMC5587585

Abstract Article PDF–1.9M

Select item 22123014.

CD28-independent, TRAF2-dependent Costimulation of Resting T Cells by 4-1BB Ligand

Katina Saoulli, Soo Young Lee, Jennifer L. Cannons, Wen Chen Yeh, Angela Santana, Marni D. Goldstein, Naveen Bangia, Mark A. DeBenedette, Tak W. Mak, Yongwon Choi, Tania H. Watts

J Exp Med. 1998 Jun 1; 187(11): 1849–1862. doi: 10.1084/jem.187.11.1849

PMCID:: PMC2212301

Abstract Article PDF–274K

Select item 1215235.

4-1BB and Ox40 Are Members of a Tumor Necrosis Factor (TNF)-Nerve Growth Factor Receptor Subfamily That Bind TNF Receptor-Associated Factors and Activate Nuclear Factor κB

Robert H. Arch, Craig B. Thompson

Mol Cell Biol. 1998 Jan; 18(1): 558–565. doi: 10.1128/mcb.18.1.558

PMCID:: PMC121523

Abstract Article PDF–589K

Select item 62245096.

Structure of the 4-1BB/4-1BBL complex and distinct binding and functional properties of utomilumab and urelumab

S. Michael Chin, Christopher R. Kimberlin, Zygy Roe-Zurz, Pamela Zhang, Allison Xu, Sindy Liao-Chan, Debasish Sen, Andrew R. Nager, Nicole Schirle Oakdale, Colleen Brown, Feng Wang, Yuting Yang, Kevin Lindquist, Yik Andy Yeung, Shahram Salek-Ardakani, Javier Chaparro-Riggers

Nat Commun. 2018; 9: 4679. Published online 2018 Nov 8. doi: 10.1038/s41467-018-07136-7

PMCID:: PMC6224509

Abstract Article PDF–2.0M

Select item 41393577.

4-1BBL Enhances CD8⁺ T Cell Responses Induced by Vectored Vaccines in Mice but Fails to Improve Immunogenicity in Rhesus Macaques

Alexandra J. Spencer, Julie Furze, Jared D. Honeycutt, Alice Calvert, Saroj Saurya, Stefano Colloca, David H. Wyllie, Sarah C. Gilbert, Migena Bregu, Matthew G. Cottingham, Adrian V. S. Hill

PLoS One. 2014; 9(8): e105520. Published online 2014 Aug 20. doi: 10.1371/journal.pone.0105520

PMCID:: PMC4139357

Abstract Article PDF–1.1M

Select item 12739018.

Development of a Ligand-Directed Approach To Study the Pathogenesis of Invasive Aspergillosis

Michail S. Lionakis, Johanna Lahdenranta, Jessica Sun, Wei Liu, Russell E. Lewis, Nathaniel D. Albert, Renata Pasqualini, Wadih Arap, Dimitrios P. Kontoyiannis

Infect Immun. 2005 Nov; 73(11): 7747–7758. doi: 10.1128/IAI.73.11.7747-7758.2005

PMCID:: PMC1273901

Abstract Article PDF–485K

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