PMC Links for Protein (Select 1064244159) - PMC

Select item 58910751.

Mutations in Diphosphoinositol-Pentakisphosphate Kinase PPIP5K2 are associated with hearing loss in human and mouse

Rizwan Yousaf, Chunfang Gu, Zubair M. Ahmed, Shaheen N. Khan, Thomas B. Friedman, Sheikh Riazuddin, Stephen B. Shears, Saima Riazuddin

PLoS Genet. 2018 Mar; 14(3): e1007297. Published online 2018 Mar 28. doi: 10.1371/journal.pgen.1007297

PMCID:: PMC5891075

Abstract Article PDF–9.4M

Select item 53777712.

The Significance of the Bifunctional Kinase/Phosphatase Activities of Diphosphoinositol Pentakisphosphate Kinases (PPIP5Ks) for Coupling Inositol Pyrophosphate Cell Signaling to Cellular Phosphate Homeostasis

Chunfang Gu, Hoai-Nghia Nguyen, Alexandre Hofer, Henning J. Jessen, Xuming Dai, Huanchen Wang, Stephen B. Shears

J Biol Chem. 2017 Mar 17; 292(11): 4544–4555. Published online 2017 Jan 26. doi: 10.1074/jbc.M116.765743

PMCID:: PMC5377771

Abstract Article PDF–2.0M

Select item 45788713.

Whole exome sequencing in extended families with autism spectrum disorder implicates four candidate genes

Nicola H. Chapman, Alejandro Q. Nato, Jr., Raphael Bernier, Katy Ankeman, Harkirat Sohi, Jeff Munson, Ashok Patowary, Marilyn Archer, Elizabeth M. Blue, Sara Jane Webb, Hilary Coon, Wendy H. Raskind, Zoran Brkanac, Ellen M. Wijsman

Hum Genet. Author manuscript; available in PMC 2016 Oct 1.

Published in final edited form as: Hum Genet. 2015 Oct; 134(10): 1055–1068. Published online 2015 Jul 24. doi: 10.1007/s00439-015-1585-y

PMCID:: PMC4578871

Abstract Article PDF–557K

Select item 44722684.

Identification of a functional nuclear translocation sequence in hPPIP5K2

Sheila T. Yong, Hoai-Nghia Nguyen, Jae H. Choi, Carl D. Bortner, Jason Williams, Niyas K. Pulloor, Manoj N. Krishnan, Stephen B. Shears

BMC Cell Biol. 2015; 16: 17. Published online 2015 Jun 18. doi: 10.1186/s12860-015-0063-7

PMCID:: PMC4472268

Abstract Article PDF–1.2M

Select item 39232635.

Structural basis for an inositol pyrophosphate kinase surmounting phosphate crowding

Huanchen Wang, J R Falck, Traci M Tanaka Hall, Stephen B Shears

Nat Chem Biol. Author manuscript; available in PMC 2014 Feb 13.

Published in final edited form as: Nat Chem Biol. 2011 Nov 27; 8(1): 111–116. Published online 2011 Nov 27. doi: 10.1038/nchembio.733

PMCID:: PMC3923263

Abstract Article PDF–3.1M

Select item 35640366.

The kinetic properties of a human PPIP5K reveal that its kinase activities are protected against the consequences of a deteriorating cellular bioenergetic environment

Jeremy D. Weaver, Huanchen Wang, Stephen B. Shears

Biosci Rep. 2013; 33(2): e00022. Prepublished online 2012 Dec 14. Published online 2013 Feb 5. doi: 10.1042/BSR20120115

PMCID:: PMC3564036

Abstract Article PDF–1.2M

Select item 26155227.

Structural Analysis and Detection of Biological Inositol Pyrophosphates Reveal That the Family of VIP/Diphosphoinositol Pentakisphosphate Kinases Are 1/3-Kinases

Hongying Lin, Peter C. Fridy, Anthony A. Ribeiro, Jae H. Choi, Deb K. Barma, Günter Vogel, J. R. Falck, Stephen B. Shears, John D. York, Georg W. Mayr

J Biol Chem. 2009 Jan 16; 284(3): 1863–1872. doi: 10.1074/jbc.M805686200

PMCID:: PMC2615522

Abstract Article PDF–1.0M

Select item 23660298.

Purification, Sequencing, and Molecular Identification of a Mammalian PP-InsP₅ Kinase That Is Activated When Cells Are Exposed to Hyperosmotic Stress

Jae H. Choi, Jason Williams, Jaiesoon Cho, J. R. Falck, Stephen B. Shears

J Biol Chem. Author manuscript; available in PMC 2008 Oct 19.

Published in final edited form as: J Biol Chem. 2007 Oct 19; 282(42): 30763–30775. Published online 2007 Aug 16. doi: 10.1074/jbc.M704655200

PMCID:: PMC2366029

Abstract Article PDF–1.3M

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