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Select item 116267621.

A comparison of the effects of ticagrelor and clopidogrel in patients with acute ST-segment elevation myocardial infarction: a systematic review and meta-analysis of randomized clinical trials

Mehdi Geravandi, Mohammad Nourabi, Sepehr Navabifar, Moein Geravandi, Zahra Hooshanginezhad, Sara Zand, Parinaz Taheri

BMC Pharmacol Toxicol. 2024; 25: 93. Published online 2024 Dec 9. doi: 10.1186/s40360-024-00817-8

PMCID:: PMC11626762

Abstract Article PDF–2.4M

Select item 116128342.

Ticagrelor vs Prasugrel for Acute Coronary Syndrome in Routine Care

Nils Krüger, Johannes Krefting, Thorsten Kessler, Raphael Schmieder, Fabian Starnecker, Alexander Dutsch, Christian Graesser, Ulrike Meyer-Lindemann, Theresa Storz, Irina Pugach, Christian Frieß, Zhifen Chen, Dario Bongiovanni, Iulian Manea, Tobias Dreischulte, Frank Offenborn, Peter Krase, Hendrik B. Sager, Jens Wiebe, Sebastian Kufner, Erion Xhepa, Michael Joner, Teresa Trenkwalder, Ulrich Gueldener, Adnan Kastrati, Salvatore Cassese, Heribert Schunkert, Moritz von Scheidt

JAMA Netw Open. 2024 Dec; 7(12): e2448389. Published online 2024 Dec 2. doi: 10.1001/jamanetworkopen.2024.48389

PMCID:: PMC11612834

Abstract Article

Select item 115839873.

Randomized evaluation of the loss‐of‐function carboxylesterase 1 (CES1) G143E variant on clopidogrel and ticagrelor pharmacodynamics

Joshua P. Lewis, Kathleen A. Ryan, Elizabeth A. Streeten, Hilary B. Whitlatch, Melanie Daue, Keith Tanner, James A. Perry, Jeffrey R. O'Connell, Alan R. Shuldiner, Braxton D. Mitchell

Clin Transl Sci. 2024 Nov; 17(11): e70079. Published online 2024 Nov 22. doi: 10.1111/cts.70079

PMCID:: PMC11583987

Abstract Article PDF–811K

Select item 114953794.

Thromboelastography with Platelet Mapping to Optimize Surgical Timing in Coronary Artery Bypass Grafting Patients on P2Y₁₂ Receptor Blockers Therapy

Pierpaolo Dambruoso, Pasquale Raimondo, Fabrizia Massaro, Margherita D'Aniello, Giuseppe Di pinto

Braz J Cardiovasc Surg. 2024 Nov-Dec; 39(6): e20230292. Published online 2024 Oct 18. doi: 10.21470/1678-9741-2023-0292

PMCID:: PMC11495379

Abstract Article PDF–205K

Select item 114818785.

Ticagrelor alters the membrane of Staphylococcus aureus and enhances the activity of vancomycin and daptomycin without eliciting cross-resistance

Kirsten Leeten, Nicolas Jacques, Lidia Alejo Esquembre, Dana C. Schneider, Jan Straetener, Camilla Henriksen, Lucia Musumeci, Florence Putters, Sofia Melo, Elena Sánchez-López, Martin Giera, Noémie Penoy, Géraldine Piel, Olivier Verlaine, Ana Amoroso, Bernard Joris, Christoph J. Slavetinsky, Eric Goffin, Bernard Pirotte, Dorte Frees, Heike Brötz-Oesterhelt, Patrizio Lancellotti, Cécile Oury

mBio. 2024 Oct; 15(10): e01322-24. Published online 2024 Sep 23. doi: 10.1128/mbio.01322-24

PMCID:: PMC11481878

Abstract Article PDF–7.1M

Select item 114580816.

Evaluation of the antiplatelet effect of generic ticagrelor 90 mg (ticaspan^®) alone and in combination with aspirin 75 mg as compared to ticagrelor (innovator): An in vitro study

S Kamat, S Jalgaonkar, P Marathe, S Karekar, D Uchil, S Revankar

J Postgrad Med. 2024 Jul-Sep; 70(3): 129–134. Published online 2023 Dec 7. doi: 10.4103/jpgm.jpgm_346_23

PMCID:: PMC11458081

Abstract Article

Select item 114320817.

Differential Effect of Omega-3 Fatty Acids on Platelet Inhibition by Antiplatelet Drugs In Vitro

Ioannis K. Koutsaliaris, Despoina Pantazi, Aikaterini N. Tsouka, Ourania Argyropoulou, Constantinos C. Tellis, Alexandros D. Tselepis

Int J Mol Sci. 2024 Sep; 25(18): 10136. Published online 2024 Sep 21. doi: 10.3390/ijms251810136

PMCID:: PMC11432081

Abstract Article PDF–1.0M

Select item 114301648.

The effect of gene polymorphism on ticagrelor metabolism: an in vitro study of 22 CYP3A4 variants in Chinese Han population

Xiaoxia Hu, Peng Wang, Dali Zeng, Guo-xin Hu

PeerJ. 2024; 12: e18109. Published online 2024 Sep 24. doi: 10.7717/peerj.18109

PMCID:: PMC11430164

Abstract Article PDF–1.2M

Select item 113832699.

Comparison of clinical outcomes between ticagrelor and clopidogrel in patients with acute coronary syndrome and left ventricle dysfunction undergoing percutaneous coronary intervention: An observational study

Caitong Zhao, Changdong Fei, Renzheng Chen, Yupeng Liu, Hualin Zhang

Medicine (Baltimore) 2024 Sep 6; 103(36): e39620. Published online 2024 Sep 6. doi: 10.1097/MD.0000000000039620

PMCID:: PMC11383269

Abstract Article PDF–792K

Select item 1138164610.

Implementing a pharmacogenomic-driven algorithm to guide antiplatelet therapy among Caribbean Hispanics: a non-randomised clinical trial

Hector J Nuñez-Medina, Mariangeli Monero, Lorna M Torres, Enrique Leal, Lorena Gonzalez-Sepulveda, Ángel M Mayor, Jessicca Y Renta, Edgardo R González-García, Ariel González, Kyle Melin, Stuart A Scott, Gualberto Ruaño, Dagmar F Hernandez-Suarez, Jorge Duconge

BMJ Open. 2024; 14(9): e084119. Published online 2024 Sep 5. doi: 10.1136/bmjopen-2024-084119

PMCID:: PMC11381646

Abstract Article PDF–1.1M

Select item 1132834211.

Precision Antiplatelet Therapy after Percutaneous Coronary Intervention (Precision PCI) Registry – Informing optimal antiplatelet strategies

Larisa H. Cavallari, Craig R. Lee, Francesco Franchi, Ellen C. Keeley, Joseph S. Rossi, Cameron D. Thomas, Yan Gong, Caitrin W. McDonough, Petr Starostik, Maryam J. Al Saeed, Latonya Been, Natasha Kulick, Jean Malave, Ian R. Mulrenin, Anh B. Nguyen, Joshua N. Terrell, Grace Tillotson, Amber L. Beitelshees, Almut G. Winterstein, George A. Stouffer, Dominick J. Angiolillo

Clin Transl Sci. 2024 Aug; 17(8): e70004. Published online 2024 Aug 16. doi: 10.1111/cts.70004

PMCID:: PMC11328342

Abstract Article PDF–862K

Select item 1126242812.

Duration of triple antithrombotic therapy and clinical outcomes after percutaneous coronary intervention in atrial fibrillation

Mark A. Sammut, Dwayne Conway, Javaid Iqbal, Arvindra Krishnamurthy, Kenneth P. Morgan, Paul D. Morris, James D. Richardson, Alexander M. K. Rothman, Julian P. Gunn, Robert F. Storey

Expert Rev Cardiovasc Ther. 2024; 22(7): 339–345. Published online 2024 Jul 1. doi: 10.1080/14779072.2024.2374366

PMCID:: PMC11262428

Abstract Article PDF–760K

Select item 1125562313.

Review of the Ticagrelor Trials Evidence Base

Grace C. Herron, Eric R. Bates

J Am Heart Assoc. 2024 Jun 4; 13(11): e031606. Published online 2024 May 28. doi: 10.1161/JAHA.123.031606

PMCID:: PMC11255623

Abstract Article PDF–464K

Select item 1125562214.

Safety, Tolerability, and Pharmacodynamics of AZD3366 (Optimized Human CD39L3 Apyrase) Alone and in Combination With Ticagrelor and Acetylsalicylic Acid: A Phase 1, Randomized, Placebo‐Controlled Study

Dimitris Kardassis, Ann‐Charlotte Egnell, Magnus Åstrand, Samuel J. Daniels, Carl Whatling, Ola Fjellström, Anders Gabrielsen

J Am Heart Assoc. 2024 Jun 4; 13(11): e033985. Published online 2024 May 28. doi: 10.1161/JAHA.123.033985

PMCID:: PMC11255622

Abstract Article PDF–797K

Select item 1122981015.

The impact of mild therapeutic hypothermia on platelet reactivity in comatose survivors of cardiac arrest with acute myocardial infarction treated with ticagrelor

Julia M. Umińska, Jakub Ratajczak, Krzysztof Pstrągowski, Katarzyna Buszko, Klaudiusz Nadolny, Tomasz Fabiszak, Klemen Steblovnik, Marko Noč, Jacek Kubica

Cardiol J. 2024; 31(3): 472–478. Published online 2024 Jun 28. doi: 10.5603/CJ.a2022.0029

PMCID:: PMC11229810

Abstract Article PDF–209K

Select item 1122456916.

Effect of Cangrelor on Infarct Size in ST-Segment–Elevation Myocardial Infarction Treated by Primary Percutaneous Coronary Intervention: A Randomized Controlled Trial (The PITRI Trial)

Heerajnarain Bulluck, Jun Hua Chong, Jennifer Bryant, Annitha Annathurai, Ping Chai, Mervyn Chan, Ashish Chawla, Chee Yang Chin, Yiu-Cho Chung, Fei Gao, Hee Hwa Ho, Andrew Fu Wah Ho, John Hoe, Syed Saqib Imran, Chi-Hang Lee, Benji Lim, Soo Teik Lim, Swee Han Lim, Boon Wah Liew, Patrick Lim Zhan Yun, Marcus Eng Hock Ong, Valeria Paradies, Xuan Ming Pung, Julian Cheong Kiat Tay, Lynette Teo, Boon Ping Ting, Aaron Wong, Evelyn Wong, Timothy Watson, Mark Y. Chan, Yeo Khung Keong, Jack W.C. Tan, Derek J. Hausenloy

Circulation. 2024 Jul 9; 150(2): 91–101. Published online 2024 May 14. doi: 10.1161/CIRCULATIONAHA.124.068938

PMCID:: PMC11224569

Abstract Article PDF–664K

Select item 1121944817.

Coronary no-reflow and adverse events in patients with acute myocardial infarction after percutaneous coronary intervention with current drug-eluting stents and third-generation P2Y₁₂ inhibitors

Gjin Ndrepepa, Salvatore Cassese, Erion Xhepa, Michael Joner, Hendrik B. Sager, Sebastian Kufner, Karl-Ludwig Laugwitz, Heribert Schunkert, Adnan Kastrati

Clin Res Cardiol. 2024; 113(7): 1006–1016. Published online 2023 Nov 14. doi: 10.1007/s00392-023-02340-y

PMCID:: PMC11219448

Abstract Article PDF–2.4M

Select item 1121940418.

Incidence and pattern of urgent revascularization in acute coronary syndromes treated with ticagrelor or prasugrel

Alp Aytekin, Maria Scalamogna, J. J. Coughlan, Shqipdona Lahu, Gjin Ndrepepa, Maurizio Menichelli, Katharina Mayer, Jochen Wöhrle, Isabell Bernlochner, Bernhard Witzenbichler, Willibald Hochholzer, Dirk Sibbing, Dominick J. Angiolillo, Rayyan Hemetsberger, Ralph Tölg, Christian Valina, Arne Müller, Sebastian Kufner, Christoph Liebetrau, Erion Xhepa, Alexander Hapfelmeier, Hendrik B. Sager, Michael Joner, Gert Richardt, Karl-Ludwig Laugwitz, Franz Josef Neumann, Heribert Schunkert, Stefanie Schüpke, Adnan Kastrati, Salvatore Cassese

Clin Res Cardiol. 2024; 113(7): 1060–1069. Published online 2024 May 13. doi: 10.1007/s00392-024-02454-x

PMCID:: PMC11219404

Abstract Article PDF–1.3M

Select item 1117991119.

Impact of Society Guidelines on Trends in Use of Newer P2Y₁₂ Inhibitors for Patients With Acute Coronary Syndromes Undergoing Percutaneous Coronary Intervention

Mohamed O. Mohamed, Evangelos Kontopantelis, Mirvat Alasnag, Leila Abid, Amitava Banerjee, Andrew S. P. Sharp, Christos Bourantas, Alex Sirker, Nick Curzen, Mamas A. Mamas

J Am Heart Assoc. 2024 May 7; 13(9): e034414. Published online 2024 May 3. doi: 10.1161/JAHA.124.034414

PMCID:: PMC11179911

Abstract Article PDF–3.0M

Select item 1117573020.

Clinical efficacy of clopidogrel and ticagrelor in patients undergoing off-pump coronary artery bypass grafting: a retrospective cohort study

Zi Wang, Runhua Ma, Xiaoyu Li, Xiaoye Li, Qing Xu, Yao Yao, Chunsheng Wang, Qianzhou Lv

Int J Surg. 2024 Jun; 110(6): 3450–3460. Published online 2024 Mar 4. doi: 10.1097/JS9.0000000000001246

PMCID:: PMC11175730

Abstract Article PDF–715K

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