PMC Articles for PubChem Compound (Select 6106) - PMC

Alvin Shrestha, Tufail Bashir, Marcus Achison, Simon Adamson, Asangaedem Akpan, Terry Aspray, Alison Avenell, Margaret M. Band, Louise A. Burton, Vera Cvoro, Peter T. Donnan, Gordon W. Duncan, Jacob George, Adam L. Gordon, Celia L. Gregson, Adrian Hapca, Cheryl Hume, Thomas A. Jackson, Simon Kerr, Alixe Kilgour, Tahir Masud, Andrew McKenzie, Emma McKenzie, Harnish Patel, Kristina Pilvinyte, Helen C. Roberts, Avan A. Sayer, Christos Rossios, Karen T. Smith, Roy L. Soiza, Claire J. Steves, Allan D. Struthers, Divya Tiwari, Julie Whitney, Miles D. Witham, Paul R. Kemp

PLoS One. 2024; 19(8): e0307268. Published online 2024 Aug 2. doi: 10.1371/journal.pone.0307268

PMCID:: PMC11296637

Abstract Article PDF–967K

Select item 112943385.

The small molecule inhibitor of SARS-CoV-2 3CLpro EDP-235 prevents viral replication and transmission in vivo

Michael H. J. Rhodin, Archie C. Reyes, Anand Balakrishnan, Nalini Bisht, Nicole M. Kelly, Joyce Sweeney Gibbons, Jonathan Lloyd, Michael Vaine, Tessa Cressey, Miranda Crepeau, Ruichao Shen, Nathan Manalo, Jonathan Castillo, Rachel E. Levene, Daniel Leonard, Tianzhu Zang, Lijuan Jiang, Kellye Daniels, Robert M. Cox, Carolin M. Lieber, Josef D. Wolf, Richard K. Plemper, Sarah R. Leist, Trevor Scobey, Ralph S. Baric, Guoqiang Wang, Bryan Goodwin, Yat Sun Or

Nat Commun. 2024; 15: 6503. Published online 2024 Aug 1. doi: 10.1038/s41467-024-50931-8

PMCID:: PMC11294338

Abstract Article PDF–1.5M

Select item 112847776.

Fixing the Achilles Heel of Pfizer’s Paxlovid for COVID-19 Treatment

Lennart Brewitz, Christopher J. Schofield

J Med Chem. 2024 Jul 25; 67(14): 11656–11661. Published online 2024 Jul 5. doi: 10.1021/acs.jmedchem.4c01342

PMCID:: PMC11284777

Abstract Article PDF–2.4M

Select item 112796187.

Serum Branched-Chain Amino Acids and Long-Term Complications of Liver Cirrhosis: Evidence from a Population-Based Prospective Study

Yichen Zhu, Chengnan Guo, Hong Fan, Xinyu Han, Yi Li, Xingdong Chen, Tiejun Zhang

Nutrients. 2024 Jul; 16(14): 2295. Published online 2024 Jul 17. doi: 10.3390/nu16142295

PMCID:: PMC11279618

Abstract Article PDF–840K

Select item 112746638.

In Silico Comparative Analysis of Ivermectin and Nirmatrelvir Inhibitors Interacting with the SARS-CoV-2 Main Protease

Yuri Alves de Oliveira Só, Katyanna Sales Bezerra, Ricardo Gargano, Fabio L. L. Mendonça, Janeusa Trindade Souto, Umberto L. Fulco, Marcelo Lopes Pereira Junior, Luiz Antônio Ribeiro Junior

Biomolecules. 2024 Jul; 14(7): 755. Published online 2024 Jun 25. doi: 10.3390/biom14070755

PMCID:: PMC11274663

Abstract Article PDF–20M

Select item 112684239.

In vitro selection and analysis of SARS-CoV-2 nirmatrelvir resistance mutations contributing to clinical virus resistance surveillance

Yuao Zhu, Irina Yurgelonis, Stephen Noell, Qingyi Yang, Shunjie Guan, Zhenghui Li, Li Hao, Hussin Rothan, Devendra K. Rai, Patricia McMonagle, Mary Lynn Baniecki, Samantha E. Greasley, Olga Plotnikova, Jonathan Lee, Jennifer A. Nicki, RoseAnn Ferre, Laura J. Byrnes, Wei Liu, Timothy K. Craig, Claire M. Steppan, Paul Liberator, Holly D. Soares, Charlotte M. N. Allerton, Annaliesa S. Anderson, Rhonda D. Cardin

Sci Adv. 2024 Jul 26; 10(30): eadl4013. Published online 2024 Jul 24. doi: 10.1126/sciadv.adl4013

PMCID:: PMC11268423

Abstract Article PDF–1.1M

Select item 1125122010.

Reconsidering the pre-eminence of dietary leucine and plasma leucinemia for predicting the stimulation of postprandial muscle protein synthesis rates

Alistair J Monteyne, Sam West, Francis B Stephens, Benjamin T Wall

Am J Clin Nutr. 2024 Jul; 120(1): 7–16. Published online 2024 May 3. doi: 10.1016/j.ajcnut.2024.04.032

PMCID:: PMC11251220

Abstract Article PDF–855K

Select item 1124754711.

The LAT1 inhibitor JPH203 suppresses the growth of castration‐resistant prostate cancer through a CD24‐mediated mechanism

Shinpei Saito, Keisuke Ando, Shinichi Sakamoto, Minhui Xu, Yasutaka Yamada, Junryo Rii, Sanji Kanaoka, Jiaxing Wei, Xue Zhao, Sangjon Pae, Manato Kanesaka, Yusuke Goto, Tomokazu Sazuka, Yusuke Imamura, Yoshie Reien, Norie Hamaguchi‐Suzuki, Shota Saito, Yuri Hirayama, Hirofumi Hashimoto, Yoshikatsu Kanai, Tomohiko Ichikawa, Naohiko Anzai

Cancer Sci. 2024 Jul; 115(7): 2461–2472. Published online 2024 Apr 24. doi: 10.1111/cas.16191

PMCID:: PMC11247547

Abstract Article PDF–1.9M

Select item 1123830412.

Cells use multiple mechanisms for cell-cycle arrest upon withdrawal of individual amino acids

Yao Rong, Alicia M. Darnell, Kiera M. Sapp, Matthew G. Vander Heiden, Sabrina L. Spencer

Cell Rep. Author manuscript; available in PMC 2024 Jul 11.

Published in final edited form as: Cell Rep. 2023 Dec 26; 42(12): 113539. Published online 2023 Dec 8. doi: 10.1016/j.celrep.2023.113539

PMCID:: PMC11238304

Abstract Article PDF–1.9M

Select item 1121395713.

A unifying model to explain frequent SARS-CoV-2 rebound after nirmatrelvir treatment and limited prophylactic efficacy

Shadisadat Esmaeili, Katherine Owens, Jessica Wagoner, Stephen J. Polyak, Judith M. White, Joshua T. Schiffer

Nat Commun. 2024; 15: 5478. Published online 2024 Jun 28. doi: 10.1038/s41467-024-49458-9

PMCID:: PMC11213957

Abstract Article PDF–9.6M

Select item 1120690014.

Protein Requirements for Maximal Muscle Mass and Athletic Performance Are Achieved with Completely Plant-Based Diets Scaled to Meet Energy Needs: A Modeling Study in Professional American Football Players

David M. Goldman, Cassandra B. Warbeck, Micaela C. Karlsen

Nutrients. 2024 Jun; 16(12): 1903. Published online 2024 Jun 17. doi: 10.3390/nu16121903

PMCID:: PMC11206900

Abstract Article PDF–619K

Select item 1118925015.

Comparison of the precursor, amino acid oxidation, and end-product methods for the evaluation of protein turnover in senior dogs

Letícia G. Pacheco, Camila Goloni, Ludmilla G. Di Santo, Lucas B. Scarpim, Débora A. Eugênio, Ariel de Castro, Vladimir E. Costa, Aulus C. Carciofi

PLoS One. 2024; 19(6): e0305073. Published online 2024 Jun 20. doi: 10.1371/journal.pone.0305073

PMCID:: PMC11189250

Abstract Article PDF–1.1M

Select item 1118867616.

Essential Amino Acid Metabolites as Chemical Mediators of Host-Microbe Interaction in the Gut

Jessica R. McCann, John F. Rawls

Annu Rev Microbiol. Author manuscript; available in PMC 2024 Jun 20.

Published in final edited form as: Annu Rev Microbiol. 2023 Sep 15; 77: 479–497. Published online 2023 Jun 20. doi: 10.1146/annurev-micro-032421-111819

PMCID:: PMC11188676

Abstract Article PDF–872K

Select item 1117280217.

SARS-CoV-2 Spike Protein Enhances Carboxypeptidase Activity of Angiotensin-Converting Enzyme 2

Xóchitl Andrea Mendiola-Salazar, Melanie A. Munguía-Laguna, Martha Franco, Agustina Cano-Martínez, José Santamaría Sosa, Rocío Bautista-Pérez

Int J Mol Sci. 2024 Jun; 25(11): 6276. Published online 2024 Jun 6. doi: 10.3390/ijms25116276

PMCID:: PMC11172802

Abstract Article PDF–2.8M

Select item 1117223918.

Development of a Biosafety Level 1 Cellular Assay for Identifying Small-Molecule Antivirals Targeting the Main Protease of SARS-CoV-2: Evaluation of Cellular Activity of GC376, Boceprevir, Carmofur, Ebselen, and Selenoneine

Yasunori Fukumoto, Noriyuki Suzuki, Reina Hara, Yu-ki Tanaka, Yasumitsu Ogra

Int J Mol Sci. 2024 Jun; 25(11): 5767. Published online 2024 May 25. doi: 10.3390/ijms25115767

PMCID:: PMC11172239

Abstract Article PDF–5.2M

Select item 1116103219.

Systematic analyses of the resistance potential of drugs targeting SARS-CoV-2 main protease

Julia M. Flynn, Qiu Yu J. Huang, Sarah N. Zvornicanin, Gila Schneider-Nachum, Ala M. Shaqra, Nese Kurt Yilmaz, Stephanie A. Moquin, Dustin Dovala, Celia A. Schiffer, Daniel N.A. Bolon

ACS Infect Dis. Author manuscript; available in PMC 2024 Jul 14.

Published in final edited form as: ACS Infect Dis. 2023 Jul 14; 9(7): 1372–1386. Published online 2023 Jun 30. doi: 10.1021/acsinfecdis.3c00125

PMCID:: PMC11161032

Abstract Article PDF–2.3M

Select item 1115992820.

Rab5a overexpression promoting ovarian cancer cell proliferation may be associated with APPL1‐related epidermal growth factor signaling pathway

Zhen Zhao, Xiang‐Fan Liu, Hua‐Cheng Wu, Shu‐Biao Zou, Jia‐Yi Wang, Pei‐Hua Ni, Xin‐Hua Chen, Qi‐Shi Fan

Cancer Sci. 2010 Jun; 101(6): 1454–1462. Published online 2010 Mar 10. doi: 10.1111/j.1349-7006.2010.01558.x

PMCID:: PMC11159928

Abstract Article PDF–2.0M

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