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Items: 1 to 20 of 111

1.
A CIA strategy with eminent drug-loading capacities for tumor ferroptosis-gas synergistic therapy
Jiaoyang Zhu, Lin Huang, Jing Yang, Zongheng Li, Lihe Wu, Wei Xiong, Jie Feng, Chenggong Yan, Chaomin Chen, Yan Li, Zheyu Shen
Theranostics. 2024; 14(19): 7349–7369. Published online 2024 Oct 28. doi: 10.7150/thno.99295
PMCID:
PMC11626936
AbstractArticlePDF–14M
2.
β-Lapachone promotes the recruitment and polarization of tumor-associated neutrophils (TANs) toward an antitumor (N1) phenotype in NQO1-positive cancers
Soumya Tumbath, Lingxiang Jiang, Xiaoguang Li, Taolan Zhang, Kashif Rafiq Zahid, Ye Zhao, Hao Zhou, Zhijun Yin, Tao Lu, Shu Jiang, Yaomin Chen, Xiang Chen, Yang-Xin Fu, Xiumei Huang
Oncoimmunology. 2024; 13(1): 2363000. Published online 2024 Jun 4. doi: 10.1080/2162402X.2024.2363000
PMCID:
PMC11155710
AbstractArticlePDF–5.6M
3.
Anticancer Potential and Safety Profile of β-Lapachone In Vitro
Karina Motta Melo Lima, Luana França Calandrini de Azevedo, Jorge Dores Rissino, Valdicley Vieira Vale, Erica Vanessa Souza Costa, Maria Fani Dolabela, Cleusa Yoshiko Nagamachi, Julio Cesar Pieczarka
Molecules. 2024 Mar; 29(6): 1395. Published online 2024 Mar 21. doi: 10.3390/molecules29061395
PMCID:
PMC10975997
AbstractArticlePDF–4.8M
4.
Multifunctional Fe-based coordination polymer nano-bomb modified with β-lapachone and CaO2 for targeted tumor dual chemodynamic therapy with enhanced ferroptosis and H2O2 self-supply
Pan Zhao, Liyang Gong, Le Chang, Huiping Du, Meijuan Geng, Siyu Meng, Liangliang Dai
J Nanobiotechnology. 2024; 22: 3. Published online 2024 Jan 3. doi: 10.1186/s12951-023-02287-2
PMCID:
PMC10763286
AbstractArticlePDF–12M
5.
Artemisia annua L. Polyphenols Enhance the Anticancer Effect of β-Lapachone in Oxaliplatin-Resistant HCT116 Colorectal Cancer Cells
Eun Joo Jung, Hye Jung Kim, Sung Chul Shin, Gon Sup Kim, Jin-Myung Jung, Soon Chan Hong, Choong Won Kim, Won Sup Lee
Int J Mol Sci. 2023 Dec; 24(24): 17505. Published online 2023 Dec 15. doi: 10.3390/ijms242417505
PMCID:
PMC10743427
AbstractArticlePDF–8.8M
6.
β-lapachone regulates mammalian inositol pyrophosphate levels in an NQO1- and oxygen-dependent manner
Verena B. Eisenbeis, Danye Qiu, Oliver Gorka, Lisa Strotmann, Guizhen Liu, Isabel Prucker, Xue Bessie Su, Miranda S. C. Wilson, Kevin Ritter, Christoph Loenarz, Olaf Groß, Adolfo Saiardi, Henning J. Jessen
Proc Natl Acad Sci U S A. 2023 Aug 22; 120(34): e2306868120. Published online 2023 Aug 14. doi: 10.1073/pnas.2306868120
PMCID:
PMC10450438
AbstractArticlePDF–2.2M
7.
β-Lapachone Exerts Anticancer Effects by Downregulating p53, Lys-Acetylated Proteins, TrkA, p38 MAPK, SOD1, Caspase-2, CD44 and NPM in Oxaliplatin-Resistant HCT116 Colorectal Cancer Cells
Eun Joo Jung, Hye Jung Kim, Sung Chul Shin, Gon Sup Kim, Jin-Myung Jung, Soon Chan Hong, Choong Won Kim, Won Sup Lee
Int J Mol Sci. 2023 Jun; 24(12): 9867. Published online 2023 Jun 7. doi: 10.3390/ijms24129867
PMCID:
PMC10298581
AbstractArticlePDF–4.2M
8.
In vitro effects of lapachol and β-lapachone against Leishmania amazonensis
Á.C.F.H. Ramos-Milaré, B.G. Sydor, A.Á. Brustolin, D.S.S.L. Lera-Nonose, J. Oyama, E.L. Silva, W. Caetano, K.S.S. Campanholi, I.G. Demarchi, T.G.V. Silveira, M.V.C. Lonardoni
Braz J Med Biol Res. 2023; 56: e12693. Published online 2023 May 29. doi: 10.1590/1414-431X2023e12693
PMCID:
PMC10229078
AbstractArticlePDF–1.3M
9.
Expanding Transition Metal-Mediated Bioorthogonal Decaging to Include C–C Bond Cleavage Reactions
Gean M. Dal Forno, Eloah Latocheski, Ana Beatriz Machado, Julie Becher, Lavinia Dunsmore, Albert L. St. John, Bruno L. Oliveira, Claudio D. Navo, Gonzalo Jiménez-Osés, Rita Fior, Josiel B. Domingos, Gonçalo J. L. Bernardes
J Am Chem Soc. 2023 May 17; 145(19): 10790–10799. Published online 2023 May 3. doi: 10.1021/jacs.3c01960
PMCID:
PMC10197128
AbstractArticlePDF–6.1M
10.
β-lapachone-mediated WST1 Reduction as Indicator for the Cytosolic Redox Metabolism of Cultured Primary Astrocytes
Patrick Watermann, Ralf Dringen
Neurochem Res. 2023; 48(7): 2148–2160. Published online 2023 Feb 22. doi: 10.1007/s11064-023-03878-z
PMCID:
PMC10182120
AbstractArticlePDF–2.6M
11.
Naphth[1,2-d]imidazoles Bioactive from β-Lapachone: Fluorescent Probes and Cytotoxic Agents to Cancer Cells
Victória Laysna dos Anjos Santos, Arlan de Assis Gonsalves, Délis Galvão Guimarães, Sidney Silva Simplicio, Helinando Pequeno de Oliveira, Lara Polyana Silva Ramos, Marcília Pinheiro da Costa, Fátima de Cássia Evangelista de Oliveira, Claudia Pessoa, Cleônia Roberta Melo Araújo
Molecules. 2023 Apr; 28(7): 3008. Published online 2023 Mar 28. doi: 10.3390/molecules28073008
PMCID:
PMC10096064
AbstractArticlePDF–1.6M
12.
A protein-based cGAS-STING nanoagonist enhances T cell-mediated anti-tumor immune responses
Xuan Wang, Yingqi Liu, Chencheng Xue, Yan Hu, Yuanyuan Zhao, Kaiyong Cai, Menghuan Li, Zhong Luo
Nat Commun. 2022; 13: 5685. Published online 2022 Sep 28. doi: 10.1038/s41467-022-33301-0
PMCID:
PMC9515186
AbstractArticlePDF–5.3M
13.
Synergistic Effect of β-Lapachone and Aminooxyacetic Acid on Central Metabolism in Breast Cancer
Mario C. Chang, Rohit Mahar, Marc A. McLeod, Anthony G. Giacalone, Xiumei Huang, David A. Boothman, Matthew E. Merritt
Nutrients. 2022 Aug; 14(15): 3020. Published online 2022 Jul 22. doi: 10.3390/nu14153020
PMCID:
PMC9331106
AbstractArticlePDF–3.1M
14.
X-ray repair cross-complementing protein 1 (XRCC1) loss promotes β-lapachone –induced apoptosis in pancreatic cancer cells
Yansong Zheng, Hengce Zhang, Yueting Guo, Yuan Chen, Hanglong Chen, Yingchun Liu
BMC Cancer. 2021; 21: 1234. Published online 2021 Nov 17. doi: 10.1186/s12885-021-08979-y
PMCID:
PMC8600733
AbstractArticlePDF–2.7M
15.
A self-amplified nanocatalytic system for achieving “1 + 1 + 1 > 3” chemodynamic therapy on triple negative breast cancer
Lulu Zhou, Jinjin Chen, Yunhao Sun, Keke Chai, Zhounan Zhu, Chunhui Wang, Mengyao Chen, Wenmei Han, Xiaochun Hu, Ruihao Li, Tianming Yao, Hui Li, Chunyan Dong, Shuo Shi
J Nanobiotechnology. 2021; 19: 261. Published online 2021 Sep 4. doi: 10.1186/s12951-021-00998-y
PMCID:
PMC8418045
AbstractArticlePDF–2.4M
16.
PCNA Inhibition Enhances the Cytotoxicity of β-Lapachone in NQO1-Positive Cancer Cells by Augmentation of Oxidative Stress-induced DNA Damage
Xiaolin Su, Jiangwei Wang, Lingxiang Jiang, Yaomin Chen, Tao Lu, Marc S Mendonca, Xiumei Huang
Cancer Lett. Author manuscript; available in PMC 2022 Oct 28.
Published in final edited form as: Cancer Lett. 2021 Oct 28; 519: 304–314. Published online 2021 Jul 27. doi: 10.1016/j.canlet.2021.07.040
PMCID:
PMC8403654
AbstractArticlePDF–2.1M
17.
STAT1 potentiates oxidative stress revealing a targetable vulnerability that increases phenformin efficacy in breast cancer
Stephanie P. Totten, Young Kyuen Im, Eduardo Cepeda Cañedo, Ouafa Najyb, Alice Nguyen, Steven Hébert, Ryuhjin Ahn, Kyle Lewis, Benjamin Lebeau, Rachel La Selva, Valérie Sabourin, Constanza Martínez, Paul Savage, Hellen Kuasne, Daina Avizonis, Nancy Santos Martínez, Catherine Chabot, Adriana Aguilar-Mahecha, Marie-Line Goulet, Matthew Dankner, Michael Witcher, Kevin Petrecca, Mark Basik, Michael Pollak, Ivan Topisirovic, Rongtuan Lin, Peter M. Siegel, Claudia L. Kleinman, Morag Park, Julie St-Pierre, Josie Ursini-Siegel
Nat Commun. 2021; 12: 3299. Published online 2021 Jun 3. doi: 10.1038/s41467-021-23396-2
PMCID:
PMC8175605
AbstractArticlePDF–7.7M
18.
Characterization and trypanocidal activity of a β-lapachone-containing drug carrier
Juliana M. C. Barbosa, Caroline D. Nicoletti, Patrícia B. da Silva, Tatiana G. Melo, Débora O. Futuro, Vitor F. Ferreira, Kelly Salomão
PLoS One. 2021; 16(3): e0246811. Published online 2021 Mar 4. doi: 10.1371/journal.pone.0246811
PMCID:
PMC7932091
AbstractArticlePDF–1.5M
19.
β-Lapachone ameliorates L-DOPA-induced dyskinesia in a 6-OHDA-induced mouse model of Parkinson's disease
Young-Kyoung Ryu, Hye-Yeon Park, Jun Go, In-Bok Lee, Young-Keun Choi, Chul-Ho Lee, Kyoung-Shim Kim
Mol Med Rep. 2021 Mar; 23(3): 217. Published online 2021 Jan 20. doi: 10.3892/mmr.2021.11856
PMCID:
PMC7845622
AbstractArticlePDF–1.5M
20.
β-Lapachone Increases Survival of Septic Mice by Regulating Inflammatory and Oxidative Response
Ana L. de B. Oliveira, Kely C. Navegantes-Lima, Valter V. S. Monteiro, Lucas B. G. Quadros, Juliana P. de Oliveira, Sávio M. dos Santos, Anna C. A. de A. Pontes, Gilson P. Dorneles, Pedro R. T. Romão, Luiz C. R. Júnior, Alaíde B. de Oliveira, Marta C. Monteiro
Oxid Med Cell Longev. 2020; 2020: 8820651. Published online 2020 Dec 12. doi: 10.1155/2020/8820651
PMCID:
PMC7749764
AbstractArticlePDF–1.4M

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