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Items: 1 to 20 of 257

1.
Indole-3-carbinol enhances ultraviolet B-induced apoptosis by sensitizing human melanoma cells
D. -S. Kim, Y. -M. Jeong, S. -I. Moon, S. -Y. Kim, S. -B. Kwon, E. -S. Park, S. -W. Youn, K. -C. Park
Cell Mol Life Sci. 2006 Nov; 63(22): 2661–2668. Published online 2006 Nov 3. doi: 10.1007/s00018-006-6306-1
PMCID:
PMC11135992
AbstractArticlePDF–355K
2.
Indole-3-carbinol attenuates lipopolysaccharide-induced acute respiratory distress syndrome through activation of AhR: role of CCR2+ monocyte activation and recruitment in the regulation of CXCR2+ neutrophils in the lungs
Bryan Latrell Holloman, Kiesha Wilson, Alkeiver Cannon, Mitzi Nagarkatti, Prakash S. Nagarkatti
Front Immunol. 2024; 15: 1330373. Published online 2024 Mar 26. doi: 10.3389/fimmu.2024.1330373
PMCID:
PMC11002125
AbstractArticlePDF–7.7M
3.
Indole-3-carbinol (I3C) reduces apoptosis and improves neurological function after cerebral ischemia–reperfusion injury by modulating microglia inflammation
Long Peng, Xingjia Zhu, Chenxing Wang, Qiaoji Jiang, Shian Yu, Gaochao Song, Qianqian Liu, Peipei Gong
Sci Rep. 2024; 14: 3145. Published online 2024 Feb 7. doi: 10.1038/s41598-024-53636-6
PMCID:
PMC10850550
AbstractArticlePDF–2.5M
4.
Cruciferous vegetable-derived indole-3-carbinol prevents coronavirus cell egression mechanisms in tracheal and intestinal 3D in vitro models.
Georgia Pennarossa, Sharon Arcuri, Rolando Pasquariello, Fulvio Gandolfi, Margherita Maranesi, Tiziana A.L. Brevini
Phytochemistry. 2023 Aug; 212: 113713. Published online 2023 May 9. doi: 10.1016/j.phytochem.2023.113713
PMCID:
PMC10168192
AbstractArticlePDF–5.5M
5.
Indole-3-Carbinol Inhibits the Growth of Endometriotic Lesions by Suppression of Microvascular Network Formation
Jeannette Rudzitis-Auth, Madeleine Becker, Claudia Scheuer, Michael D. Menger, Matthias W. Laschke
Nutrients. 2022 Nov; 14(22): 4940. Published online 2022 Nov 21. doi: 10.3390/nu14224940
PMCID:
PMC9696246
AbstractArticlePDF–3.7M
6.
The Anticancer Agent 3,3'-Diindolylmethane Inhibits Multispecies Biofilm Formation by Acne-Causing Bacteria and Candida albicans
Yong-Guy Kim, Jin-Hyung Lee, Sunyoung Park, Jintae Lee
Microbiol Spectr. 2022 Jan-Feb; 10(1): e02056-21. Published online 2022 Feb 2. doi: 10.1128/spectrum.02056-21
PMCID:
PMC8809333
AbstractArticlePDF–4.1M
7.
3,3′-Diindolylmethane Exhibits Significant Metabolism after Oral Dosing in Humans
Monica L. Vermillion Maier, Lisbeth K. Siddens, Sandra L. Uesugi, Jaewoo Choi, Scott W. Leonard, Jamie M. Pennington, Susan C. Tilton, Jordan N. Smith, Emily Ho, H.H. Sherry Chow, Bach D. Nguyen, Siva K. Kolluri, David E. Williams
Drug Metab Dispos. 2021 Aug; 49(8): 694–705. Published online 2021 Aug. doi: 10.1124/dmd.120.000346
PMCID:
PMC8407664
AbstractArticlePDF–1.0M
8.
A systems pharmacology approach based on oncogenic signalling pathways to determine the mechanisms of action of natural products in breast cancer from transcriptome data
Regan Odongo, Asuman Demiroglu-Zergeroglu, Tunahan Çakır
BMC Complement Med Ther. 2021; 21: 181. Published online 2021 Jun 30. doi: 10.1186/s12906-021-03340-z
PMCID:
PMC8244196
AbstractArticlePDF–1.8M
9.
Indole-3-Carbinol-Dependent Aryl Hydrocarbon Receptor Signaling Attenuates the Inflammatory Response in Experimental Necrotizing Enterocolitis
Lila S. Nolan, Belgacem Mihi, Pranjal Agrawal, Qingqing Gong, Jamie M. Rimer, Shay S. Bidani, Sarah E. Gale, Martin Goree, Elise Hu, Wyatt E. Lanik, Elizabeth Huang, Jennifer K. Bando, Victoria Liu, Angela N. Lewis, Aiza Bustos, Zerina Hodzic, Marie L. Laury, Misty Good
Immunohorizons. Author manuscript; available in PMC 2021 Jun 3.
Published in final edited form as: Immunohorizons. 2021 Apr 27; 5(4): 193–209. Published online 2021 Apr 27. doi: 10.4049/immunohorizons.2100018
PMCID:
PMC8173979
AbstractArticlePDF–2.3M
10.
Prenatal indole-3-carbinol administration activates aryl hydrocarbon receptor-responsive genes and attenuates lung injury in a bronchopulmonary dysplasia model 
Gabriela Guzmán-Navarro, Mario Bermúdez de León, Irene Martín-Estal, Raquel Cuevas-Díaz Durán, Laura Villarreal-Alvarado, Anakaren Vaquera-Vázquez, Tania Cuevas-Cerda, Karina Garza-García, Luis Eduardo Cuervo-Pérez, Álvaro Barbosa-Quintana, José Eduardo Pérez-Saucedo, Víctor J Lara-Díaz, Fabiola Castorena-Torres
Exp Biol Med (Maywood) 2021 Mar; 246(6): 695–706. Published online 2020 Nov 4. doi: 10.1177/1535370220963789
PMCID:
PMC7988727
AbstractArticlePDF–1.0M
11.
Inhibition of HECT E3 ligases as potential therapy for COVID-19
Giuseppe Novelli, Jing Liu, Michela Biancolella, Tonino Alonzi, Antonio Novelli, J. J. Patten, Dario Cocciadiferro, Emanuele Agolini, Vito Luigi Colona, Barbara Rizzacasa, Rosalinda Giannini, Benedetta Bigio, Delia Goletti, Maria Rosaria Capobianchi, Sandro Grelli, Justin Mann, Trevor D. McKee, Ke Cheng, Fatima Amanat, Florian Krammer, Andrea Guarracino, Gerardo Pepe, Carlo Tomino, Yacine Tandjaoui-Lambiotte, Yurdagul Uzunhan, Sarah Tubiana, Jade Ghosn, COVID Human Genetic Effort, French COVID Cohort Study Group, CoV-Contact Cohort, Luigi D. Notarangelo, Helen C. Su, Laurent Abel, Aurélie Cobat, Gai Elhanan, Joseph J. Grzymski, Andrea Latini, Sachdev S. Sidhu, Suresh Jain, Robert A. Davey, Jean-Laurent Casanova, Wenyi Wei, Pier Paolo Pandolfi
Cell Death Dis. 2021 Apr; 12(4): 310. Published online 2021 Mar 24. doi: 10.1038/s41419-021-03513-1
PMCID:
PMC7987752
AbstractArticlePDF–2.0M
12.
Maternal aryl hydrocarbon receptor activation protects newborns against necrotizing enterocolitis
Peng Lu, Yukihiro Yamaguchi, William B. Fulton, Sanxia Wang, Qinjie Zhou, Hongpeng Jia, Mark L. Kovler, Andres Gonzalez Salazar, Maame Sampah, Thomas Prindle, Jr., Peter Wipf, Chhinder P. Sodhi, David J. Hackam
Nat Commun. 2021; 12: 1042. Published online 2021 Feb 15. doi: 10.1038/s41467-021-21356-4
PMCID:
PMC7884836
AbstractArticlePDF–9.6M
13.
Dietary Indole-3-Carbinol Activates AhR in the Gut, Alters Th17-Microbe Interactions, and Exacerbates Insulitis in NOD Mice
Heather M. Kahalehili, Nolan K. Newman, Jamie M. Pennington, Siva K. Kolluri, Nancy I. Kerkvliet, Natalia Shulzhenko, Andrey Morgun, Allison K. Ehrlich
Front Immunol. 2020; 11: 606441. Published online 2021 Jan 21. doi: 10.3389/fimmu.2020.606441
PMCID:
PMC7858653
AbstractArticlePDF–2.0M
14.
Indole-3-carbinol regulates microglia homeostasis and protects the retina from degeneration
Amir Saeed Khan, Thomas Langmann
J Neuroinflammation. 2020; 17: 327. Published online 2020 Nov 3. doi: 10.1186/s12974-020-01999-8
PMCID:
PMC7640677
AbstractArticlePDF–3.6M
15.
Dietary Indole-3-Carbinol Alleviated Spleen Enlargement, Enhanced IgG Response in C3H/HeN Mice Infected with Citrobacter rodentium
Yanbei Wu, Jing Wang, Qiang He, Liangli Yu, Quynhchi Pham, Lumei Cheung, Zhi Zhang, Young S. Kim, Allen D. Smith, Thomas T. Y. Wang
Nutrients. 2020 Oct; 12(10): 3148. Published online 2020 Oct 15. doi: 10.3390/nu12103148
PMCID:
PMC7602481
AbstractArticlePDF–2.3M
16.
Immune and microRNA responses to Helicobacter muridarum infection and indole-3-carbinol during colitis
Rasha Raheem Alkarkoushi, Yvonne Hui, Abbas S Tavakoli, Udai Singh, Prakash Nagarkatti, Mitzi Nagarkatti, Ioulia Chatzistamou, Marpe Bam, Traci L Testerman
World J Gastroenterol. 2020 Aug 28; 26(32): 4763–4785. Published online 2020 Aug 28. doi: 10.3748/wjg.v26.i32.4763
PMCID:
PMC7459201
AbstractArticlePDF–5.6M
17.
Extraction and Quantification of Sulforaphane and Indole-3-Carbinol from Rapeseed Tissues Using QuEChERS Coupled with UHPLC-MS/MS
Xu Yu, Fei Ma, Liangxiao Zhang, Peiwu Li
Molecules. 2020 May; 25(9): 2149. Published online 2020 May 4. doi: 10.3390/molecules25092149
PMCID:
PMC7248958
AbstractArticlePDF–4.1M
18.
Dietary AhR Ligands Regulate AhRR Expression in Intestinal Immune Cells and Intestinal Microbiota Composition
Oliver Schanz, Rieka Chijiiwa, Sevgi Can Cengiz, Yasmin Majlesain, Heike Weighardt, Haruko Takeyama, Irmgard Förster
Int J Mol Sci. 2020 May; 21(9): 3189. Published online 2020 Apr 30. doi: 10.3390/ijms21093189
PMCID:
PMC7246938
AbstractArticlePDF–3.0M
19.
Indole-3-Carbinol Inhibits Citrobacterrodentium Infection through Multiple Pathways Including Reduction of Bacterial Adhesion and Enhancement of Cytotoxic T Cell Activity
Yanbei Wu, Qiang He, Liangli Yu, Quynhchi Pham, Lumei Cheung, Young S. Kim, Thomas T. Y. Wang, Allen D. Smith
Nutrients. 2020 Apr; 12(4): 917. Published online 2020 Mar 27. doi: 10.3390/nu12040917
PMCID:
PMC7230886
AbstractArticlePDF–2.0M
20.
The IUPHAR Guide to Immunopharmacology: connecting immunology and pharmacology
Simon D. Harding, Elena Faccenda, Christopher Southan, Adam J. Pawson, Pasquale Maffia, Stephen P. H. Alexander, Anthony P. Davenport, Doriano Fabbro, Francesca Levi‐Schaffer, Michael Spedding, Jamie A. Davies
Immunology. 2020 May; 160(1): 10–23. Published online 2020 Mar 2. doi: 10.1111/imm.13175
PMCID:
PMC7160657
AbstractArticlePDF–4.1M

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