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Items: 1 to 20 of 276

1.
Development of a genetically encoded sensor for probing endogenous nociceptin opioid peptide release
Xuehan Zhou, Carrie Stine, Patricia Oliveira Prada, Debora Fusca, Kevin Assoumou, Jan Dernic, Musadiq A. Bhat, Ananya S. Achanta, Joseph C. Johnson, Amanda Loren Pasqualini, Sanjana Jadhav, Corinna A. Bauder, Lukas Steuernagel, Luca Ravotto, Dietmar Benke, Bruno Weber, Azra Suko, Richard D. Palmiter, Miriam Stoeber, Peter Kloppenburg, Jens C. Brüning, Michael R. Bruchas, Tommaso Patriarchi
Nat Commun. 2024; 15: 5353. Published online 2024 Jun 25. doi: 10.1038/s41467-024-49712-0
PMCID:
PMC11199706
AbstractArticlePDF–12M
2.
Agonist-induced internalization and desensitization of the human nociceptin receptor expressed in CHO cells
S. Spampinato, R. Di Toro, M. Alessandri, G. Murari
Cell Mol Life Sci. 2002 Dec; 59(12): 2172–2183. doi: 10.1007/s000180200016
PMCID:
PMC11146108
AbstractArticlePDF–297K
3.
Pharmacological blockage of NOP receptors decreases ventral tegmental area dopamine neuronal activity through GABAB receptor-mediated mechanism
Michele Petrella, Anna Maria Borruto, Lorenzo Curti, Ana Domi, Esi Domi, Xu Li, Estelle Barbier, Alice Ilari, Markus Heilig, Friedbert Weiss, Guido Mannaioni, Alessio Masi, Roberto Ciccocioppo
Neuropharmacology. Author manuscript; available in PMC 2024 May 15.
Published in final edited form as: Neuropharmacology. 2024 May 1; 248: 109866. Published online 2024 Feb 15. doi: 10.1016/j.neuropharm.2024.109866
PMCID:
PMC11094429
AbstractArticlePDF–1.7M
4.
In vitro sepsis up‐regulates Nociceptin/Orphanin FQ receptor expression and function on human T‐ but not B‐cells
Mark F. Bird, Christopher P. Hebbes, Anushuya Tamang, Jonathon Mark Willets, Jonathan P. Thompson, Remo Guerrini, Girolamo Calo, David G. Lambert
Br J Pharmacol. 2023 Sep; 180(17): 2298–2314. Published online 2023 May 11. doi: 10.1111/bph.16088
PMCID:
PMC10953342
AbstractArticlePDF–7.1M
5.
Traumatic Brain Injury Induces Nociceptin/Orphanin FQ and Nociceptin Opioid Peptide Receptor Expression within 24 Hours
Omar N. Al Yacoub, Yong Zhang, Panini S. Patankar, Kelly M. Standifer
Int J Mol Sci. 2024 Feb; 25(3): 1658. Published online 2024 Jan 29. doi: 10.3390/ijms25031658
PMCID:
PMC10855772
AbstractArticlePDF–4.2M
6.
The nociceptin/orphanin FQ receptor partial agonist sunobinop promotes non-REM sleep in rodents and patients with insomnia
Garth T. Whiteside, Donald J. Kyle, Ram P. Kapil, Alessandra Cipriano, Ellie He, Mingyan Zhou, Manjunath S. Shet, Michele Hummel, Terri Knappenberger, Kazuya Fukumura, Yoshiyuki Matsuo, Masahiro Uehira, Shuichi Hiroyama, Nozomi Takai, Sandra K. Willsie, Stephen C. Harris
J Clin Invest. 2024 Jan 2; 134(1): e171172. Published online 2024 Jan 2. doi: 10.1172/JCI171172
PMCID:
PMC10760950
ArticlePDF–796K
7.
The effect of serotonergic system on nociceptin/orphanin FQ induced food intake in chicken
Morteza Zendehdel, Kasra Mokhtarpouriani, Vahab Babapour, Ali Baghbanzadeh, Maryam Pourrahimi, Shahin Hassanpour
J Physiol Sci. 2013 Jul; 63(4): 271–277. Published online 2013 Apr 25. doi: 10.1007/s12576-013-0263-x
PMCID:
PMC10717312
AbstractArticlePDF–417K
8.
Nociceptin/Orphanin FQ Opioid Peptide-Receptor Expression in the Endometriosis-Associated Nerve Fibers—Possible Treatment Option?
Qihui Guan, Renata Voltolini Velho, Alice Jordan, Sabrina Pommer, Irene Radde, Jalid Sehouli, Sylvia Mechsner
Cells. 2023 May; 12(10): 1395. Published online 2023 May 15. doi: 10.3390/cells12101395
PMCID:
PMC10216539
AbstractArticlePDF–2.8M
9.
Rostromedial tegmental nucleus nociceptin/orphanin FQ (N/OFQ) signaling regulates anxiety- and depression-like behaviors in alcohol withdrawn rats
Wenfu Li, Zhiheng Ren, Ying Tang, Yixin Fu, Shizhu Sun, Ruxuan Ding, Jiawei Hou, Yunlin Mai, Bo Zhan, Yingxin Zhu, Wanhong Zuo, Jiang-Hong Ye, Rao Fu
Neuropsychopharmacology. 2023 May; 48(6): 908–919. Published online 2022 Nov 3. doi: 10.1038/s41386-022-01482-3
PMCID:
PMC10156713
AbstractArticlePDF–3.9M
10.
Activation of the nociceptin/orphanin-FQ receptor promotes NREM sleep and EEG slow wave activity
Stephen R. Morairty, Yu Sun, Lawrence Toll, Michael R. Bruchas, Thomas S. Kilduff
Proc Natl Acad Sci U S A. 2023 Mar 28; 120(13): e2214171120. Published online 2023 Mar 22. doi: 10.1073/pnas.2214171120
PMCID:
PMC10068791
AbstractArticlePDF–3.3M
11.
The vital role of arcuate nociceptin/orphanin FQ neurones in mounting an oestradiol‐dependent adaptive response to negative energy balance via inhibition of nearby proopiomelanocortin neurones
Sarah Sayers, Nikki Le, Jennifer Hernandez, Veronica Mata‐Pacheco, Edward J. Wagner
J Physiol. 2022 Nov 15; 600(22): 4939–4961. Published online 2022 Oct 28. doi: 10.1113/JP283378
PMCID:
PMC9828807
AbstractArticlePDF–7.2M
12.
In vitro sepsis induces Nociceptin/Orphanin FQ receptor (NOP) expression in primary human vascular endothelial but not smooth muscle cells
Mark F. Bird, Barbara Gallacher-Horley, John McDonald, David G. McVey, Fatin Al-Janabi, Remo Guerrini, Girolamo Calo, Shu Ye, Jonathan P. Thompson, David G. Lambert
PLoS One. 2022; 17(9): e0274080. Published online 2022 Sep 15. doi: 10.1371/journal.pone.0274080
PMCID:
PMC9477356
AbstractArticlePDF–1.5M
13.
Current and Future Therapeutic Options in Pain Management: Multi-mechanistic Opioids Involving Both MOR and NOP Receptor Activation
Flaminia Coluzzi, Laura Rullo, Maria Sole Scerpa, Loredana Maria Losapio, Monica Rocco, Domenico Billeci, Sanzio Candeletti, Patrizia Romualdi
CNS Drugs. 2022; 36(6): 617–632. Published online 2022 May 26. doi: 10.1007/s40263-022-00924-2
PMCID:
PMC9166888
AbstractArticlePDF–946K
14.
A novel bioassay to detect Nociceptin/Orphanin FQ release from single human polymorphonuclear cells
M. F. Bird, C. P. Hebbes, S. W. M. Scott, J. Willets, J. P. Thompson, D. G. Lambert
PLoS One. 2022; 17(5): e0268868. Published online 2022 May 27. doi: 10.1371/journal.pone.0268868
PMCID:
PMC9140256
AbstractArticlePDF–1.9M
15.
Genetic Deletion or Pharmacological Blockade of Nociceptin/Orphanin FQ Receptors in the Ventral Tegmental Area Attenuates Nicotine-Motivated Behaviour
Ana Domi, Veronica Lunerti, Michele Petrella, Esi Domi, Anna Maria Borruto, Massimo Ubaldi, Friedbert Weiss, Roberto Ciccocioppo
Br J Pharmacol. Author manuscript; available in PMC 2023 Jun 1.
Published in final edited form as: Br J Pharmacol. 2022 Jun; 179(11): 2647–2658. Published online 2022 Feb 10. doi: 10.1111/bph.15762
PMCID:
PMC9081114
AbstractArticlePDF–1.0M
16.
PPL-138 (BU10038): A bifunctional NOP/mu partial agonist that reduces cocaine self-administration in rats
Andrea Cippitelli, Madeline Martinez, Gilles Zribi, Gerta Cami-Kobeci, Stephen M. Husbands, Lawrence Toll
Neuropharmacology. Author manuscript; available in PMC 2023 Jun 15.
Published in final edited form as: Neuropharmacology. 2022 Jun 15; 211: 109045. Published online 2022 Apr 1. doi: 10.1016/j.neuropharm.2022.109045
PMCID:
PMC9074796
AbstractArticlePDF–1.5M
17.
Interactions between the Nociceptin and Toll-like Receptor Systems
Lan Zhang, Ulrike M. Stamer, Melody Ying-Yu Huang, Frank Stüber
Cells. 2022 Apr; 11(7): 1085. Published online 2022 Mar 23. doi: 10.3390/cells11071085
PMCID:
PMC8997556
AbstractArticlePDF–2.2M
18.
Lack of effect of the nociceptin opioid peptide agonist Ro 64-6198 on pain-depressed behavior and heroin choice in rats
Megan Jo Moerke, S. Stevens Negus, Matthew L. Banks
Drug Alcohol Depend. Author manuscript; available in PMC 2023 Feb 1.
Published in final edited form as: Drug Alcohol Depend. 2022 Feb 1; 231: 109255. Published online 2021 Dec 30. doi: 10.1016/j.drugalcdep.2021.109255
PMCID:
PMC8810604
AbstractArticlePDF–1.0M
19.
Expression patterns of nociceptin in rats following experimental tooth movement
Lina Liao, Xiaochuan Hua, Hu Long, Niansong Ye, Yang Zhou, Sheng Wang, Wenli Lai
Angle Orthod. 2013 Nov; 83(6): 1022–1026. Published online 2013 May 8. doi: 10.2319/020913-119.1
PMCID:
PMC8722828
AbstractArticlePDF–405K
20.
Non-Opioid Peptides Targeting Opioid Effects
Katarzyna Kaczyńska, Piotr Wojciechowski
Int J Mol Sci. 2021 Dec; 22(24): 13619. Published online 2021 Dec 19. doi: 10.3390/ijms222413619
PMCID:
PMC8709238
AbstractArticlePDF–330K

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