PMC Links for OMIM (Select 600953) - PMC

Select item 108074051.

Structural insights into cytokine cleavage by inflammatory caspase-4

Pascal Devant, Ying Dong, Julian Mintseris, Weiyi Ma, Steven P. Gygi, Hao Wu, Jonathan C. Kagan

Nature. Author manuscript; available in PMC 2024 Jun 1.

Published in final edited form as: Nature. 2023 Dec; 624(7991): 451–459. Published online 2023 Nov 22. doi: 10.1038/s41586-023-06751-9

Correction in:: Nature. 2024 Jan 3

PMCID:: PMC10807405

Abstract Article PDF–6.9M

Select item 73813642.

IL-18BP is a secreted immune checkpoint and barrier to IL-18 immunotherapy

Ting Zhou, William Damsky, Orr-El Weizman, Meaghan K. McGeary, K. Patricia Hartmann, Connor E. Rosen, Suzanne Fischer, Ruaidhri Jackson, Richard A. Flavell, Jun Wang, Miguel F. Sanmamed, Marcus W. Bosenberg, Aaron M. Ring

Nature. Author manuscript; available in PMC 2020 Dec 24.

Published in final edited form as: Nature. 2020 Jul; 583(7817): 609–614. Published online 2020 Jun 24. doi: 10.1038/s41586-020-2422-6

PMCID:: PMC7381364

Abstract Article PDF–6.7M

Select item 49430283.

Epithelial IL-18 Equilibrium Controls Barrier Function in Colitis

Roni Nowarski, Ruaidhrí Jackson, Nicola Gagliani, Marcel R. de Zoete, Noah W. Palm, Will Bailis, Jun Siong Low, Christian C.D. Harman, Morven Graham, Eran Elinav, Richard A. Flavell

Cell. Author manuscript; available in PMC 2016 Jul 13.

Published in final edited form as: Cell. 2015 Dec 3; 163(6): 1444–1456. doi: 10.1016/j.cell.2015.10.072

PMCID:: PMC4943028

Abstract Article PDF–5.4M

Select item 48684564.

Targeting IL-17A attenuates neonatal sepsis mortality induced by IL-18

James Lawrence Wynn, Chris S. Wilson, Jacek Hawiger, Philip O. Scumpia, Andrew F. Marshall, Jin-Hua Liu, Irina Zharkikh, Hector R. Wong, Patrick Lahni, John T. Benjamin, Erin J. Plosa, Jörn-Hendrik Weitkamp, Edward R. Sherwood, Lyle L. Moldawer, Ricardo Ungaro, Henry V. Baker, M. Cecilia Lopez, Steven J. McElroy, Natacha Colliou, Mansour Mohamadzadeh, Daniel Jensen Moore

Proc Natl Acad Sci U S A. 2016 May 10; 113(19): E2627–E2635. Published online 2016 Apr 25. doi: 10.1073/pnas.1515793113

PMCID:: PMC4868456

Abstract Article PDF–2.7M

Select item 47884085.

Prevention and cure of rotavirus infection via TLR5/NLRC4–mediated production of IL-22 and IL-18

Benyue Zhang, Benoit Chassaing, Zhenda Shi, Robin Uchiyama, Zhan Zhang, Timothy L. Denning, Sue E. Crawford, Andrea J. Pruijssers, Jason A. Iskarpatyoti, Mary K. Estes, Terence S. Dermody, Wenjun Ouyang, Ifor R. Williams, Matam Vijay-Kumar, Andrew T. Gewirtz

Science. Author manuscript; available in PMC 2016 Mar 11.

Published in final edited form as: Science. 2014 Nov 14; 346(6211): 861–865. doi: 10.1126/science.1256999

PMCID:: PMC4788408

Abstract Article PDF–471K

Select item 46715016.

Deletion of ripA Alleviates Suppression of the Inflammasome and MAPK by Francisella tularensis

Max Tze-Han Huang, Brittany L. Mortensen, Debra J. Taxman, Robin R. Craven, Sharon Taft-Benz, Todd M. Kijek, James R. Fuller, Beckley K. Davis, Irving Coy Allen, Willie June Brickey, Denis Gris, Haitao Wen, Thomas H. Kawula, Jenny Pan-Yun Ting

J Immunol. Author manuscript; available in PMC 2015 Dec 7.

Published in final edited form as: J Immunol. 2010 Nov 1; 185(9): 5476–5485. Published online 2010 Oct 4. doi: 10.4049/jimmunol.1002154

PMCID:: PMC4671501

Abstract Article PDF–862K

Select item 32766827.

Inflammasome-mediated dysbiosis regulates progression of NAFLD and obesity

Jorge Henao-Mejia, Eran Elinav, Cheng-Cheng Jin, Liming Hao, Wajahat Z. Mehal, Till Strowig, Christoph A. Thaiss, Andrew L. Kau, Stephanie C. Eisenbarth, Michael J. Jurczak, Joao-Paulo Camporez, Gerald I. Shulman, Jeffrey I. Gordon, Hal M. Hoffman, Richard A. Flavell

Nature. Author manuscript; available in PMC 2012 Aug 9.

Published in final edited form as: Nature. 2012 Feb 9; 482(7384): 179–185. Published online 2012 Feb 1. doi: 10.1038/nature10809

PMCID:: PMC3276682

Abstract Article PDF–2.1M

Select item 21936808.

Interleukin-18 Regulates Acute Graft-Versus-Host Disease by Enhancing Fas-mediated Donor T Cell Apoptosis

Pavan Reddy, Takanori Teshima, Mark Kukuruga, Rainer Ordemann, Chen Liu, Kathy Lowler, James L.M. Ferrara

J Exp Med. 2001 Nov 19; 194(10): 1433–1440. doi: 10.1084/jem.194.10.1433

PMCID:: PMC2193680

Abstract Article PDF–92K

Select item 17820659.

Enhanced viral clearance in interleukin-18 gene-deficient mice after pulmonary infection with influenza A virus

Koenraad F Van Der Sluijs, Leontine J R Van Elden, Ramon Arens, Monique Nijhuis, Rob Schuurman, Sandrine Florquin, Joan Kwakkel, Shizuo Akira, Henk M Jansen, René Lutter, Tom Van Der Polls

Immunology. 2005 Jan; 114(1): 112–120. doi: 10.1111/j.1365-2567.2004.02000.x

PMCID:: PMC1782065

Abstract Article PDF–277K

Select item 50782010.

Active stage of autoimmune diabetes is associated with the expression of a novel cytokine, IGIF, which is located near Idd2.

H Rothe, N A Jenkins, N G Copeland, H Kolb

J Clin Invest. 1997 Feb 1; 99(3): 469–474. doi: 10.1172/JCI119181

PMCID:: PMC507820

Summary PDF–228K

Select item 50780611.

IFN-gamma, IGIF, and IDDM.

N Sarvetnick

J Clin Invest. 1997 Feb 1; 99(3): 371–372. doi: 10.1172/JCI119167

PMCID:: PMC507806

Summary PDF–74K

Select item 28356612.

IL-18 cDNA vaccination protects mice from spontaneous lupus-like autoimmune disease

Paola Bossù, Detlef Neumann, Elda Del Giudice, Antonio Ciaramella, Isabelle Gloaguen, Giamila Fantuzzi, Charles A. Dinarello, Emma Di Carlo, Piero Musiani, Pier Luigi Meroni, Gianfranco Caselli, Paolo Ruggiero, Diana Boraschi

Proc Natl Acad Sci U S A. 2003 Nov 25; 100(24): 14181–14186. Published online 2003 Nov 13. doi: 10.1073/pnas.2336094100

PMCID:: PMC283566

Abstract Article PDF–465K

Select item 12325813.

IL-18 contributes to the spontaneous development of atopic dermatitis-like inflammatory skin lesion independently of IgE/stat6 under specific pathogen-free conditions

Hiroshi Konishi, Hiroko Tsutsui, Takaaki Murakami, Shizue Yumikura-Futatsugi, Kei-ichi Yamanaka, Minoru Tanaka, Yohichiro Iwakura, Noboru Suzuki, Kiyoshi Takeda, Shizuo Akira, Kenji Nakanishi, Hitoshi Mizutani

Proc Natl Acad Sci U S A. 2002 Aug 20; 99(17): 11340–11345. Published online 2002 Jul 31. doi: 10.1073/pnas.152337799

PMCID:: PMC123258

Abstract Article PDF–301K

Select item 1539914.

IL-18 regulates IL-1β-dependent hepatic melanoma metastasis via vascular cell adhesion molecule-1

Fernando Vidal-Vanaclocha, Giamila Fantuzzi, Lorea Mendoza, Angela M. Fuentes, Miren J. Anasagasti, Javier Martín, Teresa Carrascal, Patrick Walsh, Leonid L. Reznikov, Soo-Hyun Kim, Daniela Novick, Menachem Rubinstein, Charles A. Dinarello

Proc Natl Acad Sci U S A. 2000 Jan 18; 97(2): 734–739. doi: 10.1073/pnas.97.2.734

PMCID:: PMC15399

Abstract Article PDF–225K

PMC

Result Filters

Article attributes

Text availability

Publication date

Custom date range

Research Funder

Additional filters

Display Settings:

Send to:

Links from OMIM

Items: 14

Display Settings:

Send to:

Supplemental Content

Find related data

Recent activity