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Items: 14

Select item 74026271.

Structural basis of a shared antibody response to SARS-CoV-2

Meng Yuan, Hejun Liu, Nicholas C. Wu, Chang-Chun D. Lee, Xueyong Zhu, Fangzhu Zhao, Deli Huang, Wenli Yu, Yuanzi Hua, Henry Tien, Thomas F. Rogers, Elise Landais, Devin Sok, Joseph G. Jardine, Dennis R. Burton, Ian A. Wilson

Science. 2020 Aug 28; 369(6507): 1119–1123. Published online 2020 Jul 13. doi: 10.1126/science.abd2321

PMCID:: PMC7402627

Abstract Article PDF–1.2M

Select item 73289812.

Structural basis of receptor recognition by SARS-CoV-2

Jian Shang, Gang Ye, Ke Shi, Yushun Wan, Chuming Luo, Hideki Aihara, Qibin Geng, Ashley Auerbach, Fang Li

Nature. Author manuscript; available in PMC 2020 Sep 30.

Published in final edited form as: Nature. 2020 May; 581(7807): 221–224. Published online 2020 Mar 30. doi: 10.1038/s41586-020-2179-y

PMCID:: PMC7328981

Abstract Article PDF–1.7M

Select item 71646373.

Cryo-EM structure of the 2019-nCoV spike in the prefusion conformation

Daniel Wrapp, Nianshuang Wang, Kizzmekia S. Corbett, Jory A. Goldsmith, Ching-Lin Hsieh, Olubukola Abiona, Barney S. Graham, Jason S. McLellan

Science. 2020 Mar 13; 367(6483): 1260–1263. Published online 2020 Feb 19. doi: 10.1126/science.abb2507

PMCID:: PMC7164637

Abstract Article PDF–815K

Select item 71646354.

Structural basis for the recognition of SARS-CoV-2 by full-length human ACE2

Renhong Yan, Yuanyuan Zhang, Yaning Li, Lu Xia, Yingying Guo, Qiang Zhou

Science. 2020 Mar 27; 367(6485): 1444–1448. Published online 2020 Mar 4. doi: 10.1126/science.abb2762

PMCID:: PMC7164635

Abstract Article PDF–1.6M

Select item 71446195.

Structural and Functional Basis of SARS-CoV-2 Entry by Using Human ACE2

Qihui Wang, Yanfang Zhang, Lili Wu, Sheng Niu, Chunli Song, Zengyuan Zhang, Guangwen Lu, Chengpeng Qiao, Yu Hu, Kwok-Yung Yuen, Qisheng Wang, Huan Zhou, Jinghua Yan, Jianxun Qi

Cell. 2020 May 14; 181(4): 894–904.e9. Published online 2020 Apr 9. doi: 10.1016/j.cell.2020.03.045

PMCID:: PMC7144619

Abstract Article PDF–5.0M

Select item 71380976.

Identification of an alternative 5′‐untranslated exon and new polymorphisms of angiotensin‐converting enzyme 2 gene: Lack of association with SARS in the Vietnamese population

Satoru Itoyama, Naoto Keicho, Minako Hijikata, Tran Quy, Nguyen Chi Phi, Hoang Thuy Long, Le Dang Ha, Vo Van Ban, Ikumi Matsushita, Hideki Yanai, Fumiko Kirikae, Teruo Kirikae, Tadatoshi Kuratsuji, Takehiko Sasazuki

Am J Med Genet A. 2005 Jul 1; 136A(1): 52–57. Published online 2005 Jun 3. doi: 10.1002/ajmg.a.30779

PMCID:: PMC7138097

Abstract Article PDF–79K

Select item 71026277.

SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor

Markus Hoffmann, Hannah Kleine-Weber, Simon Schroeder, Nadine Krüger, Tanja Herrler, Sandra Erichsen, Tobias S. Schiergens, Georg Herrler, Nai-Huei Wu, Andreas Nitsche, Marcel A. Müller, Christian Drosten, Stefan Pöhlmann

Cell. 2020 Apr 16; 181(2): 271–280.e8. Published online 2020 Mar 5. doi: 10.1016/j.cell.2020.02.052

PMCID:: PMC7102627

Abstract Article PDF–5.3M

Select item 70957838.

A crucial role of angiotensin converting enzyme 2 (ACE2) in SARS coronavirus–induced lung injury

Keiji Kuba, Yumiko Imai, Shuan Rao, Hong Gao, Feng Guo, Bin Guan, Yi Huan, Peng Yang, Yanli Zhang, Wei Deng, Linlin Bao, Binlin Zhang, Guang Liu, Zhong Wang, Mark Chappell, Yanxin Liu, Dexian Zheng, Andreas Leibbrandt, Teiji Wada, Arthur S Slutsky, Depei Liu, Chuan Qin, Chengyu Jiang, Josef M Penninger

Nat Med. 2005; 11(8): 875–879. Published online 2005 Jul 10. doi: 10.1038/nm1267

PMCID:: PMC7095783

Abstract Article PDF–1.0M

Select item 70953159.

ACE2 links amino acid malnutrition to microbial ecology and intestinal inflammation

Tatsuo Hashimoto, Thomas Perlot, Ateequr Rehman, Jean Trichereau, Hiroaki Ishiguro, Magdalena Paolino, Verena Sigl, Toshikatsu Hanada, Reiko Hanada, Simone Lipinski, Birgit Wild, Simone M. R. Camargo, Dustin Singer, Andreas Richter, Keiji Kuba, Akiyoshi Fukamizu, Stefan Schreiber, Hans Clevers, Francois Verrey, Philip Rosenstiel, Josef M. Penninger

Nature. 2012; 487(7408): 477–481. Published online 2012 Jul 25. doi: 10.1038/nature11228

PMCID:: PMC7095315

Abstract Article PDF–1.5M

Select item 709501610.

Angiotensin-converting enzyme 2 is a functional receptor for the SARS coronavirus

Wenhui Li, Michael J. Moore, Natalya Vasilieva, Jianhua Sui, Swee Kee Wong, Michael A. Berne, Mohan Somasundaran, John L. Sullivan, Katherine Luzuriaga, Thomas C. Greenough, Hyeryun Choe, Michael Farzan

Nature. 2003; 426(6965): 450–454. doi: 10.1038/nature02145

PMCID:: PMC7095016

Abstract Article PDF–1.9M

Select item 709499811.

Angiotensin-converting enzyme 2 protects from severe acute lung failure

Yumiko Imai, Keiji Kuba, Shuan Rao, Yi Huan, Feng Guo, Bin Guan, Peng Yang, Renu Sarao, Teiji Wada, Howard Leong-Poi, Michael A. Crackower, Akiyoshi Fukamizu, Chi-Chung Hui, Lutz Hein, Stefan Uhlig, Arthur S. Slutsky, Chengyu Jiang, Josef M. Penninger

Nature. 2005; 436(7047): 112–116. doi: 10.1038/nature03712

PMCID:: PMC7094998

Abstract Article PDF–1.4M

Select item 151878912.

Altered blood pressure responses and normal cardiac phenotype in ACE2-null mice

Susan B. Gurley, Alicia Allred, Thu H. Le, Robert Griffiths, Lan Mao, Nisha Philip, Timothy A. Haystead, Mary Donoghue, Roger E. Breitbart, Susan L. Acton, Howard A. Rockman, Thomas M. Coffman

J Clin Invest. 2006 Aug 1; 116(8): 2218–2225. Published online 2006 Jul 27. doi: 10.1172/JCI16980

PMCID:: PMC1518789

Abstract Article PDF–489K

Select item 114235813.

Human coronavirus NL63 employs the severe acute respiratory syndrome coronavirus receptor for cellular entry

Heike Hofmann, Krzysztof Pyrc, Lia van der Hoek, Martina Geier, Ben Berkhout, Stefan Pöhlmann

Proc Natl Acad Sci U S A. 2005 May 31; 102(22): 7988–7993. Published online 2005 May 16. doi: 10.1073/pnas.0409465102

PMCID:: PMC1142358

Abstract Article PDF–482K

Select item 52483614.

CD209L (L-SIGN) is a receptor for severe acute respiratory syndrome coronavirus

Scott A. Jeffers, Sonia M. Tusell, Laura Gillim-Ross, Erin M. Hemmila, Jenna E. Achenbach, Gregory J. Babcock, William D. Thomas, Jr., Larissa B. Thackray, Mark D. Young, Robert J. Mason, Donna M. Ambrosino, David E. Wentworth, James C. DeMartini, Kathryn V. Holmes

Proc Natl Acad Sci U S A. 2004 Nov 2; 101(44): 15748–15753. Published online 2004 Oct 20. doi: 10.1073/pnas.0403812101