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Items: 3

Select item 59339351.

Drug-tolerant persister cancer cells are vulnerable to GPX4 inhibition

Matthew J. Hangauer, Vasanthi S. Viswanathan, Matthew J. Ryan, Dhruv Bole, John K. Eaton, Alexandre Matov, Jacqueline Galeas, Harshil D. Dhruv, Michael E. Berens, Stuart L. Schreiber, Frank McCormick, Michael T. McManus

Nature. Author manuscript; available in PMC 2018 May 3.

Published in final edited form as: Nature. 2017 Nov 9; 551(7679): 247–250. Published online 2017 Nov 1. doi: 10.1038/nature24297

PMCID:: PMC5933935

Abstract Article PDF–1.4M

Select item 56679002.

Dependency of a therapy-resistant state of cancer cells on a lipid peroxidase pathway

Vasanthi S. Viswanathan, Matthew J. Ryan, Harshil D. Dhrav, Shubhroz Gill, Ossia M. Eichhoff, Brinton Seashore-Ludlow, Samuel D. Kaffenberger, John K. Eaton, Kenichi Shimada, Andrew J. Aguirre, Srinivas R. Viswanathan, Shrikanta Chattopadhyay, Pablo Tamayo, Wan Seok Yang, Matthew G. Rees, Sixun Chen, Zarko V Boskovic, Sarah Javaid, Cherrie Huang, Xiaoyun Wu, Yuen-Yi Tseng, Elisabeth M. Roider, Dong Gao, James M. Cleary, Brian M. Wolpin, Jill P. Mesirov, Daniel A. Haber, Jeffrey A. Engelman, Jesse S. Boehm, Joanne D. Kotz, Cindy S. Hon, YU Chen, William C. Hahn, Mitchell P. Levesque, John G. Doench, Michael E. Berens, Alykhan F. Shamji, Paul A. Clemons, Brent R. Stockwell, Stuart L. Schreiber

Nature. Author manuscript; available in PMC 2018 Jul 27.

Published in final edited form as: Nature. 2017 Jul 27; 547(7664): 453–457. Published online 2017 Jul 5. doi: 10.1038/nature23007