PMC Links for OMIM (Select 133435) - PMC

Select item 37325351.

A stable transcription factor complex nucleated by oligomeric AML1-ETO controls leukaemogenesis

Xiao-Jian Sun, Zhanxin Wang, Lan Wang, Yanwen Jiang, Nils Kost, T. David Soong, Wei-Yi Chen, Zhanyun Tang, Tomoyoshi Nakadai, Olivier Elemento, Wolfgang Fischle, Ari Melnick, Dinshaw J. Patel, Stephen D. Nimer, Robert G. Roeder

Nature. Author manuscript; available in PMC 2014 Feb 1.

Published in final edited form as: Nature. 2013 Aug 1; 500(7460): 93–97. Published online 2013 Jun 30. doi: 10.1038/nature12287

PMCID:: PMC3732535

Abstract Article PDF–1.3M

Select item 32510122.

The Leukemogenicity of AML1-ETO Is Dependent on Site-Specific Lysine Acetylation

Lan Wang, Alexander Gural, Xiao-Jian Sun, Xinyang Zhao, Fabiana Perna, Gang Huang, Megan A. Hatlen, Ly Vu, Fan Liu, Haiming Xu, Takashi Asai, Hao Xu, Tony Deblasio, Silvia Menendez, Francesca Voza, Yanwen Jiang, Philip A. Cole, Jinsong Zhang, Ari Melnick, Robert G. Roeder, Stephen D. Nimer

Science. Author manuscript; available in PMC 2012 Jan 4.

Published in final edited form as: Science. 2011 Aug 5; 333(6043): 765–769. Published online 2011 Jul 14. doi: 10.1126/science.1201662

PMCID:: PMC3251012

Abstract Article PDF–1.1M

Select item 24231493.

ETO, but Not Leukemogenic Fusion Protein AML1/ETO, Augments RBP-Jκ/SHARP-Mediated Repression of Notch Target Genes

Daniela Salat, Robert Liefke, Jörg Wiedenmann, Tilman Borggrefe, Franz Oswald

Mol Cell Biol. 2008 May; 28(10): 3502–3512. Published online 2008 Mar 10. doi: 10.1128/MCB.01966-07

PMCID:: PMC2423149

Abstract Article PDF–1.2M

Select item 22233854.

Myeloid Translocation Gene Family Members Associate with T-Cell Factors (TCFs) and Influence TCF-Dependent Transcription

Amy C. Moore, Joseph M. Amann, Christopher S. Williams, Emilios Tahinci, Tiffany E. Farmer, J. Andres Martinez, Genyan Yang, K. Scott Luce, Ethan Lee, Scott W. Hiebert

Mol Cell Biol. 2008 Feb; 28(3): 977–987. Published online 2007 Nov 26. doi: 10.1128/MCB.01242-07

PMCID:: PMC2223385

Abstract Article PDF–484K

Select item 21941085.

AML1-ETO Inhibits Maturation of Multiple Lymphohematopoietic Lineages and Induces Myeloblast Transformation in Synergy with ICSBP Deficiency

Maike Schwieger, Jürgen Löhler, Jutta Friel, Marina Scheller, Ivan Horak, Carol Stocking

J Exp Med. 2002 Nov 4; 196(9): 1227–1240. doi: 10.1084/jem.20020824

PMCID:: PMC2194108

Abstract Article PDF–527K

Select item 5547926.

AML1-ETO fusion protein up-regulates TRKA mRNA expression in human CD34⁺ cells, allowing nerve growth factor-induced expansion

James C. Mulloy, Vladimir Jankovic, Mark Wunderlich, Ruud Delwel, Jorg Cammenga, Ondrej Krejci, Hui Zhao, Peter J. M. Valk, Bob Lowenberg, Stephen D. Nimer

Proc Natl Acad Sci U S A. 2005 Mar 15; 102(11): 4016–4021. Published online 2005 Feb 24. doi: 10.1073/pnas.0404701102

PMCID:: PMC554792

Abstract Article PDF–441K

Select item 5240437.

Stem cell expression of the AML1/ETO fusion protein induces a myeloproliferative disorder in mice

Timothy S. Fenske, Gina Pengue, Vikram Mathews, Piia T. Hanson, Sarah E. Hamm, Noor Riaz, Timothy A. Graubert

Proc Natl Acad Sci U S A. 2004 Oct 19; 101(42): 15184–15189. Published online 2004 Oct 11. doi: 10.1073/pnas.0400751101

PMCID:: PMC524043

Abstract Article PDF–519K

Select item 4135218.

The t(8;21) translocation in acute myeloid leukemia results in production of an AML1-MTG8 fusion transcript.

H Miyoshi, T Kozu, K Shimizu, K Enomoto, N Maseki, Y Kaneko, N Kamada, M Ohki

EMBO J. 1993 Jul; 12(7): 2715–2721. doi: 10.1002/j.1460-2075.1993.tb05933.x

PMCID:: PMC413521

Summary Page Browse PDF–1.4M

Select item 1266159.

Acute myeloid leukemias with reciprocal rearrangements can be distinguished by specific gene expression profiles

Claudia Schoch, Alexander Kohlmann, Susanne Schnittger, Benedikt Brors, Martin Dugas, Susanne Mergenthaler, Wolfgang Kern, Wolfgang Hiddemann, Roland Eils, Torsten Haferlach

Proc Natl Acad Sci U S A. 2002 Jul 23; 99(15): 10008–10013. Published online 2002 Jul 8. doi: 10.1073/pnas.142103599

PMCID:: PMC126615

Abstract Article PDF–261K

Select item 8878910.

Oligomerization of ETO Is Obligatory for Corepressor Interaction

Jinsong Zhang, Bruce A. Hug, Eric Y. Huang, Clarice W. Chen, Vania Gelmetti, Marco Maccarana, Saverio Minucci, Pier Giuseppe Pelicci, Mitchell A. Lazar

Mol Cell Biol. 2001 Jan; 21(1): 156–163. doi: 10.1128/MCB.21.1.156-163.2001

PMCID:: PMC88789

Abstract Article PDF–2.1M

Select item 8728611.

Gene Targeting Reveals a Crucial Role for MTG8 in the Gut

Franco Calabi, Richard Pannell, Gordana Pavloska

Mol Cell Biol. 2001 Aug; 21(16): 5658–5666. doi: 10.1128/MCB.21.16.5658-5666.2001

PMCID:: PMC87286

Abstract Article PDF–1.9M

Select item 5294212.

t(8;21) breakpoints on chromosome 21 in acute myeloid leukemia are clustered within a limited region of a single gene, AML1.

H Miyoshi, K Shimizu, T Kozu, N Maseki, Y Kaneko, M Ohki

Proc Natl Acad Sci U S A. 1991 Dec 1; 88(23): 10431–10434. doi: 10.1073/pnas.88.23.10431

PMCID:: PMC52942

Summary Page Browse PDF–965K

Select item 1657813.

AML1/ETO-expressing nonleukemic stem cells in acute myelogenous leukemia with 8;21 chromosomal translocation

Toshihiro Miyamoto, Irving L. Weissman, Koichi Akashi

Proc Natl Acad Sci U S A. 2000 Jun 20; 97(13): 7521–7526. doi: 10.1073/pnas.97.13.7521

PMCID:: PMC16578

Abstract Article PDF–350K

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