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Select item 60080571.

Genetic ablation of Cyp8b1 preserves host metabolic function by repressing steatohepatitis and altering gut microbiota composition

Jay V. Patankar, Chi K. Wong, Vijay Morampudi, William T. Gibson, Bruce Vallance, George N. Ioannou, Michael R. Hayden

Am J Physiol Endocrinol Metab. 2018 May 1; 314(5): E418–E432. Published online 2017 Oct 24. doi: 10.1152/ajpendo.00172.2017

PMCID:: PMC6008057

Abstract Article

Select item 55828852.

Cyp8b1 ablation prevents Western diet-induced weight gain and hepatic steatosis because of impaired fat absorption

Enrico Bertaggia, Kristian K. Jensen, Jose Castro-Perez, Yimeng Xu, Gilbert Di Paolo, Robin B. Chan, Liangsu Wang, Rebecca A. Haeusler

Am J Physiol Endocrinol Metab. 2017 Aug 1; 313(2): E121–E133. Published online 2017 Apr 4. doi: 10.1152/ajpendo.00409.2016

PMCID:: PMC5582885

Abstract Article

Select item 55183173.

Zinc Fingers and Homeoboxes 2 (Zhx2) Regulates Sexually Dimorphic Cyp Gene Expression in the Adult Mouse Liver

Kate Townsend Creasy, Jieyun Jiang, Hui Ren, Martha L. Peterson, Brett T. Spear

Gene Expr. 2016; 17(1): 7–17. Published online 2016 May 17. doi: 10.3727/105221616X691712

PMCID:: PMC5518317

Abstract Article PDF–8.5M

Select item 49188444.

Cholesterol 7α-hydroxylase-deficient mice are protected from high-fat/high-cholesterol diet-induced metabolic disorders

Jessica M. Ferrell, Shannon Boehme, Feng Li, John Y. L. Chiang

J Lipid Res. 2016 Jul; 57(7): 1144–1154. doi: 10.1194/jlr.M064709

PMCID:: PMC4918844

Abstract Article PDF–1.3M

Select item 47329835.

Mice Abundant in Muricholic Bile Acids Show Resistance to Dietary Induced Steatosis, Weight Gain, and to Impaired Glucose Metabolism

Ylva Bonde, Gösta Eggertsen, Mats Rudling

PLoS One. 2016; 11(1): e0147772. Published online 2016 Jan 29. doi: 10.1371/journal.pone.0147772

PMCID:: PMC4732983

Abstract Article PDF–830K

Select item 1508026.

Cholic acid mediates negative feedback regulation of bile acid synthesis in mice

Jia Li-Hawkins, Mats Gåfvels, Maria Olin, Erik G. Lund, Ulla Andersson, Gertrud Schuster, Ingemar Björkhem, David W. Russell, Gosta Eggertsen

J Clin Invest. 2002 Oct 15; 110(8): 1191–1200. doi: 10.1172/JCI16309

PMCID:: PMC150802

Abstract Article PDF–1.2M

Select item 68816657.

Impaired Intestinal Farnesoid X Receptor Signaling in Cystic Fibrosis Mice

Pauline T. Ikpa, Marcela Doktorova, Kelly F. Meijsen, Natascha D.A. Nieuwenhuijze, Henkjan J. Verkade, Johan W. Jonker, Hugo R. de Jonge, Marcel J.C. Bijvelds

Cell Mol Gastroenterol Hepatol. 2020; 9(1): 47–60. Published online 2019 Aug 27. doi: 10.1016/j.jcmgh.2019.08.006

PMCID:: PMC6881665

Abstract Article PDF–2.1M

Select item 62701178.

Repeated Oral Administration of Oleanolic Acid Produces Cholestatic Liver Injury in Mice

Yuan-Fu Lu, Xiao-Li Wan, Yasha Xu, Jie Liu

Molecules. 2013 Mar; 18(3): 3060–3071. Published online 2013 Mar 7. doi: 10.3390/molecules18033060

PMCID:: PMC6270117

Abstract Article PDF–660K

Select item 59642369.

Long non-coding RNA Gm2199 rescues liver injury and promotes hepatocyte proliferation through the upregulation of ERK1/2

Qiang Gao, Yunyan Gu, Yanan Jiang, Li Fan, Zixiang Wei, Haobin Jin, Xirui Yang, Lijuan Wang, Xuguang Li, Sheng Tai, Baofeng Yang, Yan Liu

Cell Death Dis. 2018 Jun; 9(6): 602. Published online 2018 May 22. doi: 10.1038/s41419-018-0595-9

PMCID:: PMC5964236

Abstract Article PDF–3.5M

Select item 563358810.

Metabolomic and transcriptomic profiling of hepatocellular carcinomas in Hras12V transgenic mice

Tingting Fan, Zhuona Rong, Jianyi Dong, Juan Li, Kangwei Wang, Xinxin Wang, Huiling Li, Jun Chen, Fujin Wang, Jingyu Wang, Aiguo Wang

Cancer Med. 2017 Oct; 6(10): 2370–2384. Published online 2017 Sep 21. doi: 10.1002/cam4.1177

PMCID:: PMC5633588

Abstract Article PDF–721K

Select item 537777611.

Berberine-induced Inactivation of Signal Transducer and Activator of Transcription 5 Signaling Promotes Male-specific Expression of a Bile Acid Uptake Transporter

Pengli Bu, Yuan Le, Yue Zhang, Youcai Zhang, Xingguo Cheng

J Biol Chem. 2017 Mar 17; 292(11): 4602–4613. Published online 2017 Feb 1. doi: 10.1074/jbc.M116.757567

PMCID:: PMC5377776

Abstract Article PDF–2.9M

Select item 494396012.

Protective Vaccination against Blood-Stage Malaria of Plasmodium chabaudi: Differential Gene Expression in the Liver of Balb/c Mice toward the End of Crisis Phase

Saleh A. Al-Quraishy, Mohamed A. Dkhil, Abdel-Azeem A. Abdel-Baki, Denis Delic, Frank Wunderlich

Front Microbiol. 2016; 7: 1087. Published online 2016 Jul 14. doi: 10.3389/fmicb.2016.01087

PMCID:: PMC4943960

Abstract Article PDF–2.6M

Select item 402926613.

Lack of P2Y₁₃ in mice fed a high cholesterol diet results in decreased hepatic cholesterol content, biliary lipid secretion and reverse cholesterol transport

Laeticia Lichtenstein, Nizar Serhan, Wijtske Annema, Guillaume Combes, Bernard Robaye, Jean-Marie Boeynaems, Bertrand Perret, Uwe J F Tietge, Muriel Laffargue, Laurent O Martinez

Nutr Metab (Lond) 2013; 10: 67. Published online 2013 Nov 6. doi: 10.1186/1743-7075-10-67

PMCID:: PMC4029266

Abstract Article PDF–338K

Select item 380887014.

Candidate genes for limiting cholestatic intestinal injury identified by gene expression profiling

Samuel M Alaish, Jennifer Timmons, Alexis Smith, Marguerite S Buzza, Ebony Murphy, Aiping Zhao, Yezhou Sun, Douglas J Turner, Terez Shea-Donahue, Toni M Antalis, Alan Cross, Susan G Dorsey

Physiol Rep. 2013 Sep; 1(4): e00073. Published online 2013 Sep 17. doi: 10.1002/phy2.73

PMCID:: PMC3808870

Abstract Article PDF–1.2M

Select item 356943815.

Lack of the Matricellular Protein SPARC (Secreted Protein, Acidic and Rich in Cysteine) Attenuates Liver Fibrogenesis in Mice

Catalina Atorrasagasti, Estanislao Peixoto, Jorge B. Aquino, Néstor Kippes, Mariana Malvicini, Laura Alaniz, Mariana Garcia, Flavia Piccioni, Esteban J. Fiore, Juan Bayo, Ramón Bataller, Elizabeth Guruceaga, Fernando Corrales, Osvaldo Podhajcer, Guillermo Mazzolini

PLoS One. 2013; 8(2): e54962. Published online 2013 Feb 11. doi: 10.1371/journal.pone.0054962